Production of Single-Chain Fv Antibodies Specific for GA-Pyridine, an Advanced Glycation End-Product (AGE), with Reduced Inter-Domain Motion

Autor: Natsuki Fukuda, Kentaro Noi, Lidong Weng, Yoshihiro Kobashigawa, Hiromi Miyazaki, Yukari Wakeyama, Michiyo Takaki, Yusuke Nakahara, Yuka Tatsuno, Makiyo Uchida-Kamekura, Yoshiaki Suwa, Takashi Sato, Naoki Ichikawa-Tomikawa, Motoyoshi Nomizu, Yukio Fujiwara, Fumina Ohsaka, Takashi Saitoh, Katsumi Maenaka, Hiroyuki Kumeta, Shoko Shinya, Chojiro Kojima, Teru Ogura, Hiroshi Morioka

Publikováno v: Molecules, Vol 22, Iss 10, p 1695 (2017)

Due to their lower production cost compared with monoclonal antibodies, single-chain variable fragments (scFvs) have potential for use in several applications, such as for diagnosis and treatment of a range of diseases, and as sensor elements. Howeve

Externí odkaz: https://doaj.org/article/ec91204768074e62bae41965348e2ac8

Production of Single-Chain Fv Antibodies Specific for GA-Pyridine, an Advanced Glycation End-Product (AGE), with Reduced Inter-Domain Motion

Autor: Hiroyuki Kumeta, Hiroshi Morioka, Shoko Shinya, Natsuki Fukuda, Yusuke Nakahara, Katsumi Maenaka, Takashi Sato, Yukari Wakeyama, Hiromi Miyazaki, Fumina Ohsaka, Yoshihiro Kobashigawa, Makiyo Uchida-Kamekura, Naoki Ichikawa-Tomikawa, Kentaro Noi, Teru Ogura, Yoshiaki Suwa, Yukio Fujiwara, Motoyoshi Nomizu, Yuka Tatsuno, Takashi Saitoh, Lidong Weng, Michiyo Takaki, Chojiro Kojima

Publikováno v: Molecules; Volume 22; Issue 10; Pages: 1695
Molecules, Vol 22, Iss 10, p 1695 (2017)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry

Due to their lower production cost compared with monoclonal antibodies, single-chain variable fragments (scFvs) have potential for use in several applications, such as for diagnosis and treatment of a range of diseases, and as sensor elements. Howeve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1028e17abe75bd4f98c15f3a91a380f0