Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Yukari Terashima"'
Autor:
Shuichi Hamada, Miyuki Shigano, Satoru Kawakami, Maya Ueda, Hajime Sui, Katsuya Yamada, Soichiro Hagio, Ayaka Momonami, Akihisa Maeda, Yukari Terashima, Wakako Ohyama, Takeshi Morita, Makoto Hayashi
Publikováno v:
Genes and Environment, Vol 41, Iss 1, Pp 1-8 (2019)
Abstract Background The repeated-dose liver micronucleus (RDLMN) assay is an effective and important in vivo test for detecting genotoxic compounds, particularly for those that require metabolic activation to show genotoxicity. In a collaborative stu
Externí odkaz:
https://doaj.org/article/c18356cee9e44b748aa005238a282ea6
Autor:
Ayaka Momonami, Soichiro Hagio, Satoru Kawakami, Akihisa Maeda, Hajime Sui, Miyuki Shigano, Katsuya Yamada, Takeshi Morita, Wakako Ohyama, Maya Ueda, Shuichi Hamada, Makoto Hayashi, Yukari Terashima
Publikováno v:
Genes and Environment
Genes and Environment, Vol 41, Iss 1, Pp 1-8 (2019)
Genes and Environment, Vol 41, Iss 1, Pp 1-8 (2019)
Background The repeated-dose liver micronucleus (RDLMN) assay is an effective and important in vivo test for detecting genotoxic compounds, particularly for those that require metabolic activation to show genotoxicity. In a collaborative study by the
Autor:
Yumi Wako, Kazufumi Kawasako, Toru Tamura, Yukari Terashima, Ryohei Yokoi, Erika Saitou, Ikuro Takakura, Shinji Souma
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. :36-40
To assess the effectiveness of the multiple dose liver micronucleus (MN) assay, the induction of micronuclei by N-nitrosodi-n-propylamine (NDPA), a genotoxic rodent carcinogen, was compared in hepatocytes (HEPs) and bone marrow (BM) cells. Young adul
Autor:
Yukari Terashima, Kazuto Terada, Kazuo Ohkuma, Nomintsetseg Batbayar, Natsuki Sano, Takashi Kameda
Publikováno v:
Orthodontic Waves. 73:55-60
Purpose This article reviews the development of a compact autoclave with a dramatically shortened running time that did not compromise the quality of its sterilization properties including orthodontic appliances, orthodontic mini-implants (anchor scr
Autor:
Mami Yamamoto, Kazuyoshi Ishii, Yukari Terashima, Misao Abe, Shuji Onishi, Manabu Yamaoka, Madoka Inoue, Shosaku Nomura
Publikováno v:
Japanese Journal of Transfusion and Cell Therapy. 60:471-476
Autor:
Ryohei Yokoi, Tomoya Onozato, Yoshimasa Maruyama, Junji Kuroda, Hiroshi Kusama, Dianne M. Creasy, Ikuro Takakura, Toru Tamura, Tomonobu Chino, Toru Tahara, Yukari Terashima
Publikováno v:
The Journal of Toxicological Sciences. 39:269-279
Wistar Hannover rats have been utilized as one of major strains in regulatory toxicology studies. This study was performed to verify the appropriate age of male sexual maturity in the development and reproductive toxicity (DART) study in Wistar Hanno
Autor:
Tadashi Imamura, Yasushi Shimada, Yukari Terashima, Akihisa Maeda, Makoto Hayashi, Kazuo Kobayashi, Hironao Takasawa, Masayoshi Kawabata, Hirotaka Matsumoto, Hiroshi Suzuki, Atsushi Miyazaki, Keiyu Oshida, Izumi Ogawa, Ryo Ohta, Shigenori Minowa
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 698:24-29
A collaborative study was conducted to evaluate whether a liver micronucleus assay using four-week-old male F344 rats can be used to detect genotoxic rat hepatocarcinogens using double-dosing with a single-sampling 4 days after the second dose. The a
Autor:
Yasushi Shimada, Atsushi Miyazaki, Yukari Terashima, Tadashi Imamura, Kazuo Kobayashi, Hiroshi Suzuki, Hironao Takasawa, Jin Tanaka, Izumi Ogawa, Makoto Hayashi
Publikováno v:
Mutagenesis. 24:9-16
The partial hepatectomy method, co-treatment method with mitogens and an in vivo/in vitro assay method have been reported as in vivo liver micronucleus (MN) assays. These methods have disadvantages with respect to widespread use as an in vivo assay,
Autor:
Shoji Matsumura, Hironao Takasawa, Hajime Kojima, Makoto Hayashi, Hajime Sui, Yumi Wako, Yasushi Shimada, Nobuyuki Ohashi, Masamitsu Honma, Emiko Okada, Takeshi Morita, Satoru Kawakami, Wakako Ohyama, Tomomi Takayanagi, Yosuke Ogiwara, Izumi Ogawa, Shigeharu Muto, Masaki Sano, Kenji Inoue, Hisakazu Sanada, Kazunori Narumi, Keisuke Shimada, Aya Hayashi, Kazufumi Kawasako, Kazumi Matsumoto, Fuyumi Uno, Akihisa Maeda, Rie Takashima, Shuichi Hamada, Tadashi Imamura, Yukari Terashima
Publikováno v:
Mutation research. Genetic toxicology and environmental mutagenesis.
The repeated-dose liver micronucleus (RDLMN) assay using young adult rats has the potential to detect hepatocarcinogens. We conducted a collaborative study to assess the performance of this assay and to evaluate the possibility of integrating it into
Autor:
Yukiko Saito, Koko Nagaoka, Jin Tanaka, Makoto Hayashi, Takayoshi Suzuki, Shigeki Hatakeyama, Yukari Terashima, Naohiro Ikeda, Toshiyuki Hagiwara, Junichi Yoshida, Yasushi Shimada, Kazuo Kobayashi, Hiroshi Suzuki
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 583:133-145
We conducted simultaneous liver and peripheral blood micronucleus assays in young rats with seven rodent hepatocarcinogens-4,4'-methylenedianiline (MDA), quinoline, o-toluidine, 4-chloro-o-phenylenediamine (CPDA), dimethylnitrosamine (DMN), p-dimethy