Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Yukari Shiwaku"'
Autor:
Takanori Hatakeyama, Ryo Hamai, Yukari Shiwaku, Takahisa Anada, Susumu Sakai, Tomoya Sato, Kazuyoshi Baba, Keiichi Sasaki, Osamu Suzuki
Publikováno v:
Science and Technology of Advanced Materials, Vol 24, Iss 1 (2023)
ABSTRACTThe objective of this study was to determine whether degradation products from spongy gelatin scaffolds can enhance angiogenesis and orthotopic bone regeneration. Spongy gelatin disks were prepared using gelatin solution concentrations rangin
Externí odkaz:
https://doaj.org/article/e87da3257dca400abfa7e941d2fcbab6
Autor:
Shinki Koyama, Ryo Hamai, Yukari Shiwaku, Tsuyoshi Kurobane, Kaori Tsuchiya, Tetsu Takahashi, Osamu Suzuki
Publikováno v:
Science and Technology of Advanced Materials, Vol 23, Iss 1, Pp 120-139 (2022)
The objective of this study is to investigate the effects of octacalcium phosphate (OCP)-induced bone regeneration on angiogenesis regulated by the inclusion of copper ions in OCP in vitro and in vivo. Calcium (Ca)-deficient Cu-OCPs, containing 0.01
Externí odkaz:
https://doaj.org/article/03120c6260224990a6476a77d8f6ba89
Publikováno v:
Science and Technology of Advanced Materials, Vol 22, Iss 1, Pp 345-362 (2021)
This study examined the effect of a mixture of octacalcium phosphate (OCP) and autologous bone on bone regeneration in rat calvaria critical-sized defect (CSD). Mechanically mixed OCP and autologous bone granules (OCP+Auto), approximately 500 to 1000
Externí odkaz:
https://doaj.org/article/69b198b297374d0887c5bb0879c11e00
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1235 (2023)
Synthetic octacalcium phosphate (OCP) activates bone tissue-related cells, such as osteoblasts, osteoclasts, and vascular endothelial cells. However, the effect of OCP on tendon-related cell activation remains unknown. This study examined the respons
Externí odkaz:
https://doaj.org/article/eb7b6be8d99146f6bbae276f0c6f7e84
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 11252 (2021)
Calcium phosphate (CaP) materials influence macrophage polarization during bone healing. However, the effect of the crystal phase of CaP materials on the immune response of bone remains unclear. In this study, the effect of the crystal phases of CaP
Externí odkaz:
https://doaj.org/article/73ba8525863a40bd85a3623ce795f71b
Autor:
Yukari Shiwaku, Ryo Hamai, Shinichi Sato, Susumu Sakai, Kaori Tsuchiya, Kazuyoshi Baba, Tetsu Takahashi, Osamu Suzuki
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9770 (2021)
The microstructure of biomaterials influences the cellular and biological responses in the bone. Octacalcium phosphate (OCP) exhibits higher biodegradability and osteoconductivity than hydroxyapatite (HA) during the conversion process from OCP to HA.
Externí odkaz:
https://doaj.org/article/6e366744d0404eef9074fcf3fe723539
Autor:
Takahisa Anada, Tomoya Sato, Takuo Kamoya, Yukari Shiwaku, Kaori Tsuchiya, Teruko Takano-Yamamoto, Keiichi Sasaki, Osamu Suzuki
Publikováno v:
Regenerative Therapy, Vol 3, Iss C, Pp 58-62 (2016)
Much attention has been paid to three-dimensional cell culture systems in the field of regenerative medicine, since three-dimensional cellular aggregates, or spheroids, are thought to better mimic the in vivo microenvironments compared to conventiona
Externí odkaz:
https://doaj.org/article/1af02b09114142889751fe974997fdd1
Autor:
Yukari Shiwaku, Lynn Neff, Kenichi Nagano, Ken-Ichi Takeyama, Joost de Bruijn, Michel Dard, Francesca Gori, Roland Baron
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132903 (2015)
Biphasic calcium phosphates (BCPs), consisting of hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP), exhibit good biocompatibility and osteoconductivity, maintaining a balance between resorption of the biomaterial and formation of new bone. We
Externí odkaz:
https://doaj.org/article/fe1aebde3b7a424ab70e1bf0c791edef
Autor:
Soshi Hamada, Yu Mori, Yukari Shiwaku, Ryo Hamai, Kaori Tsuchiya, Kazuyoshi Baba, Itsuki Oizumi, Ryuichi Kanabuchi, Naohisa Miyatake, Toshimi Aizawa, Osamu Suzuki
Publikováno v:
Clin Orthop Relat Res
BACKGROUND: Bone grafting is widely used to treat large bone defects. A porous composite of a bioactive octacalcium phosphate material with gelatin sponge (OCP/Gel) has been shown to biodegrade promptly and be replaced with new bone both in animal mo
Autor:
Kyosuke Okuyama, Yukari Shiwaku, Ryo Hamai, Toshihide Mizoguchi, Kaori Tsuchiya, Tetsu Takahashi, Osamu Suzuki
Publikováno v:
Acta Biomaterialia. 142:332-344
This study aimed to investigate the accumulation and differentiation of mesenchymal stem cells (MSCs) around octacalcium phosphate (OCP) compared with those around calcium-deficient hydroxyapatite (CDHA), a material obtained through hydrolysis of the