Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yukari Kimoto"'
Autor:
Takuya Orita, Masafumi Inoue, Tomoya Miura, Yoshinori Hara, Makoto Shiozaki, Hiroshi Yamamoto, Shingo Obika, Hiroshi Yamanaka, Chika Oki, Yukari Kimoto, Yoshihiro Ogawa, Tsuyoshi Adachi, Atsuo Tanimoto, Akimi Hori, Satoru Noji, Hiromasa Hashimoto, Yasunori Hase, Tamotsu Negoro, Satoki Doi, Katsuya Maeda
Publikováno v:
Journal of medicinal chemistry. 63(13)
Dermatologic disorders such as atopic dermatitis arise from genetic and environmental causes and are complex and multifactorial in nature. Among possible risk factors, aberrant immunological reactions are one of the leading etiologies. Immunosuppress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd05e59507e421fd4174fd9eaec2f08d
https://pubmed.ncbi.nlm.nih.gov/32511913
https://pubmed.ncbi.nlm.nih.gov/32511913
Autor:
Eriko Taniai-Riya, Mikio Hayashi, Yasuo Yamamoto, Yuichi Shinozaki, Atsuo Tanimoto, Kochi Kakimoto, Wataru Amano, Yoshiaki Katsuda, Yukari Kimoto, Kaoru Toyoda, Noriko Konishi
Publikováno v:
Experimental dermatology. 27(1)
Janus kinases (JAKs) are required for several inflammatory cytokine signalling pathways and are implicated in the pathogenesis of chronic dermatitis, including atopic dermatitis and psoriasis. JAK inhibitors are therefore promising therapeutic candid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd6e9c50f18a3f0dc7cea861ad4b33a
https://pubmed.ncbi.nlm.nih.gov/28423239
https://pubmed.ncbi.nlm.nih.gov/28423239
Autor:
Keisuke Nozawa, Chika Oki, Akira Matsuo, Satoru Noji, Makoto Shiozaki, Yukari Kimoto, Yoshihiro Ogawa, Mutsuyoshi Matsushita, Yuichi Shinozaki, Atsuo Tanimoto, Wataru Amano
Publikováno v:
Inflammation Research
Objective To evaluate the pharmacological properties of JTE-052, a novel Janus kinase (JAK) inhibitor. Methods The JAK inhibitory activity of JTE-052 was evaluated using recombinant human enzymes. The inhibitory effects on cytokine signaling pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::870969c258798b723b8374b6d77c20db
https://doi.org/10.1007/s00011-014-0782-9
https://doi.org/10.1007/s00011-014-0782-9
Autor:
Yuta Gotoda, Serina Kita, Ken Lukowiak, Ryo Kawai, Akira Kanazawa, Yukari Kimoto, Ryuji Hashiba, Saya Ueki, Dai Hatakeyama, Naohisa Nara, Etsuro Ito, Ryoko Suzuki, Yoshito Abe, Eriko Uraki, Yutaka Fujito
Publikováno v:
The Biological bulletin. 220(1)
In conditioned taste aversion (CTA) training performed on the pond snail Lymnaea stagnalis, a stimulus (the conditional stimulus, CS; e.g., sucrose) that elicits a feeding response is paired with an aversive stimulus (the unconditional stimulus, US)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039cad04cd57ee82c90f5297eab0b7cb
https://pubmed.ncbi.nlm.nih.gov/21385959
https://pubmed.ncbi.nlm.nih.gov/21385959
Autor:
Yasuharu Numata, Akihiko Kitoh, Yoshiki Miyachi, Teruki Dainichi, Gyohei Egawa, Yasuo Yamamoto, Kenji Kabashima, Atsushi Otsuka, Tetsuya Honda, Wataru Amano, Yukari Kimoto, Hayato Kunugi, Saeko Nakajima, Mutsuyoshi Matsushita, Atsuo Tanimoto
Publikováno v:
Journal of Allergy and Clinical Immunology. 136:667-677.e7
Background Barrier disruption and the resulting continuous exposure to allergens are presumed to be responsible for the development of atopic dermatitis (AD). However, the mechanism through which skin barrier function is disrupted in patients with AD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76ce7581c44bb5fecf8d7ce973d2207
https://doi.org/10.1016/j.jaci.2015.03.051
https://doi.org/10.1016/j.jaci.2015.03.051
Autor:
Yukari Kimoto, Wataru Amano, Keisuke Nozawa, Akira Matsuo, Yuichi Shinozaki, Atsuo Tanimoto, Takayuki Yamaguchi, Mutsuyoshi Matsushita
Publikováno v:
BMC Musculoskeletal Disorders
Background Rheumatoid arthritis (RA) is a chronic inflammatory disease that leads to joint destruction, disability, and decreased quality of life (QOL). Inhibition of Janus kinase (JAK) signaling ameliorates articular inflammation and joint destructi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d55b614eec22373c8ef75cfd68152886