Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yukana Nakaima"'
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64425 (2013)
CD137 is a member of the tumor necrosis factor receptor family that is expressed on activated T cells. This molecule provides a co-stimulatory signal that enhances the survival, and differentiation of cells, and has a crucial role in the development
Externí odkaz:
https://doaj.org/article/07162c764ba54cfeb7cef4aa9d5c55d3
Autor:
Shizuo Akira, Yukana Nakaima, David Savitsky, ZhiChao Wang, Yan Lu, Tadatsugu Taniguchi, Hideyuki Yanai, Tatsuma Ban, Sho Hangai, Makoto Nakasato, Kenya Honda, Myoung Kwon Choi, Tomohiko Tamura, Osamu Takeuchi, Ryuji Koshiba, Hideo Negishi
Publikováno v:
Proceedings of the National Academy of Sciences. 106:17870-17875
The activation of the innate immune responses by DNA exposed within the cytosol has gained much attention and, in this context, several cytosolic DNA sensors have been identified. However, previous studies revealed the operation of redundant and comp
Autor:
Tomohiko Tamura, Shigeru Noguchi, Tomohiko Oh, Yukana Nakaima, Keishiro Nishimura, Akira Nakajima, Tadatsugu Taniguchi
Publikováno v:
Proceedings of the National Academy of Sciences. 106:12448-12452
The generation of mice lacking the expression of the IRF3 transcription factor ( Irf3 −/− mice) has revealed its crucial role in the activation of the type I IFN response. The Bcl2l12 gene, encoding Bcl2L12 protein structurally related to the Bcl
Autor:
Hideyuki Yanai, Yukana Nakaima, Tatsuma Ban, Takashi Onoe, Kenya Honda, Tadatsugu Taniguchi, Shiho Chiba, Hideki Ohdan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 108(28)
The activation of innate immune responses by nucleic acids is central to the generation of host responses against pathogens; however, nucleic acids can also trigger the development and/or exacerbation of pathogenic responses such as autoimmunity. We
Autor:
Takatoshi Koyama, Ken Watanabe, Laura Z. Rassenti, Aya Kasubata, Thomas J. Kipps, Osamu Miura, Yukana Nakaima, Tetsuya Fukuda
Publikováno v:
Blood. 114:1266-1266
Abstract 1266 Poster Board I-288 CD137/4-1BB, a TNFR family member is expressed on activated T cells as a co-stimulator. It transduces the signal for cell survival and differentiation and plays a crucial role in CD8 cytotoxic T cells. Recently, an in
Autor:
Myoung Kwon Choi, ZhiChao Wang, Tatsuma Ban, Hideyuki Yanai, Van Lu, Ryuji Koshiba, Yukana Nakaima, Sho Hangai, Savitsky, David, Nakasato, Makoto, Negishi, Hideo, Takeuchi, Osamu, Honda, Kenya, Akira, Shizuo, Tamura, Tomohiko, Taniguchi, Tadatsugu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 10/20/2009, Vol. 106 Issue 42, p17870-17875, 6p, 3 Graphs