Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Yukako Saito"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 1595-1618 (2018)
To synthesize nucleoside and oligosaccharide derivatives, we often use a glycosylation reaction to form a glycoside bond. Coupling reactions between a nucleobase and a sugar donor in the former case, and the reaction between an acceptor and a sugar d
Externí odkaz:
https://doaj.org/article/53296d15fdc24051a71c2038a2dea7c3
Autor:
Ryo Kitamura, Tsugunobu Andoh, Shizuka Mizoguchi, Yukako Saito, Hiroki Takahata, Yasushi Kuraishi
Publikováno v:
Journal of Pharmacological Sciences, Vol 124, Iss 4, Pp 502-510 (2014)
Bortezomib, an inhibitor of proteasome holoenzyme, is used to treat relapsed and refractory multiple myeloma. Peripheral neuropathy is a treatment-limiting adverse effect of bortezomib and is very difficult to control. In this study, we examined the
Externí odkaz:
https://doaj.org/article/dc8f33b7c5584415810e97834da51352
Publikováno v:
Molecules, Vol 18, Iss 1, Pp 1162-1173 (2013)
Synthesis of beneficial protected meso-DAP 9 by cross metathesis of the Garner aldehyde-derived vinyl glycine 1b with protected allyl glycine 2 in the presence of Grubbs second-generation catalyst was performed. Preparation of lipophilic N-acyl iE-DA
Externí odkaz:
https://doaj.org/article/edbffe903a7e4bd18819c14c29874c55
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 3, Iss 1, p 37 (2007)
The asymmetric synthesis of both enantiomers of piclavines A1, A2, A3, and A4 has been achieved using an iterative asymmetric dihydroxylation with enantiomeric enhancement.
Externí odkaz:
https://doaj.org/article/89b435c9136d47d3a0491f14a9a80138
Autor:
Youhei Kikuchi, Ayano Takahashi, Yuichi Yoshimura, Madoka Sasaki, Yukako Saito, Yoshihiro Natori, Ayaka Ishii, Hideaki Wakamatsu
Publikováno v:
Organic Letters. 22:5299-5303
A palladium-catalyzed regioselective three-component coupling of ynamides was developed. The reaction proceeded smoothly to furnish the desired products when carried out at 70 °C in acetonitrile/water with potassium carbonate in the presence of 2.5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac613de344490636502d56d977cd3d54
https://doi.org/10.1021/acs.orglett.0c01426
https://doi.org/10.1021/acs.orglett.0c01426
Publikováno v:
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 1595-1618 (2018)
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 1595-1618 (2018)
To synthesize nucleoside and oligosaccharide derivatives, we often use a glycosylation reaction to form a glycoside bond. Coupling reactions between a nucleobase and a sugar donor in the former case, and the reaction between an acceptor and a sugar d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de502c1e842e8bbad37badae015379a
https://doi.org/10.3762/bjoc.14.137
https://doi.org/10.3762/bjoc.14.137
Publikováno v:
Scopus-Elsevier
Many attempts have been made to synthesize structurally novel nucleoside derivatives in order to identify effective compounds for the treatment of tumors and virus-caused disease. At our laboratories, as part of our efforts to synthesize 4'-thionucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a38ae0905e5a09043f2d53aae3d7cd
https://pubmed.ncbi.nlm.nih.gov/29386464
https://pubmed.ncbi.nlm.nih.gov/29386464
Autor:
Nozomi Shoji, Kozue Nitta, Yuichi Yoshimura, Yoshihiro Natori, Hideaki Wakamatsu, Yukako Saito
Publikováno v:
Current Protocols in Nucleic Acid Chemistry. 71
The detailed practical synthesis of 4'-thionucleosides starting from L-arabinose is described here. 1,4-Anhydro-2,3-O-isopropylidene-4-thioribitol, which is the key intermediate for the synthesis of 4'-thionucleosides, is obtained from L-arabinose in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd90f573d81d362c26ac09d1c038b71b
https://doi.org/10.1002/cpnc.45
https://doi.org/10.1002/cpnc.45
Autor:
Yukako Saito, Yuichi Yoshimura, Hiroki Takahata, Shun Omoto, Tomozumi Imamichi, Hiroya Kan-no, Hideaki Wakamatsu, Sakie Minato, Yoshihiro Natori
Publikováno v:
Synthesis. 46:879-886
As a part of our ongoing studies of structure–activity relationships regarding cyclohexenyl nucleosides, we were prompted to synthesize a dihydropyranonucleoside as a potential anti-HIV agent. The synthesis of a glycal moiety started from but-2-ene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67a3a8d8894e28d8e2597c656fc58b36
https://doi.org/10.1055/s-0033-1340663
https://doi.org/10.1055/s-0033-1340663
Autor:
Tsugunobu Andoh, Yukako Saito, Hiroki Takahata, Yasushi Kuraishi, Shizuka Mizoguchi, Ryo Kitamura
Publikováno v:
Journal of Pharmacological Sciences, Vol 124, Iss 4, Pp 502-510 (2014)
Bortezomib, an inhibitor of proteasome holoenzyme, is used to treat relapsed and refractory multiple myeloma. Peripheral neuropathy is a treatment-limiting adverse effect of bortezomib and is very difficult to control. In this study, we examined the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7b5108fd9821719ea4dae00a304a02
https://doi.org/10.1254/jphs.13274fp
https://doi.org/10.1254/jphs.13274fp