Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Yukako Nishimura"'
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41413 (2012)
Polarized microtubule (MT) growth in the leading edge is critical to directed cell migration, and is mediated by Rac1 GTPase. To find downstream targets of Rac1 that affect MT assembly dynamics, we performed an RNAi screen of 23 MT binding and regula
Externí odkaz:
https://doaj.org/article/5a24cb1613144e958bbed941a8b474c2
Autor:
Yukako NISHIMURA
Publikováno v:
Seibutsu Butsuri. 63:24-26
REF52 fibroblasts have a well-developed contractile machinery, the most prominent elements of which are actomyosin stress fibers with highly ordered organization of actin and myosin IIA filaments. The relationship between contractile activity and tur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f98a879992c539e83ebe704c627fad0
https://doi.org/10.1101/2021.08.15.456175
https://doi.org/10.1101/2021.08.15.456175
Autor:
James R. Sellers, Rong Liu, Yukako Nishimura, Yasuharu Takagi, Fang Zhang, Shidong Shi, Virgile Viasnoff, Alexander D. Bershadsky
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The small molecular inhibitor of formin FH2 domains, SMIFH2, is widely used in cell biological studies. It inhibits formin-driven actin polymerization in vitro, but not polymerization of pure actin. It is active against several types of formin from d
Autor:
Ana M. Pasapera, Sarah M. Heissler, Masumi Eto, Yukako Nishimura, Robert S. Fischer, Hawa R. Thiam, Clare M. Waterman
Publikováno v:
Curr Biol
Cancer cell migration during metastasis is mediated by a highly polarized cytoskeleton. MARK2 and its invertebrate homologue Par1B are kinases that regulate the microtubule cytoskeleton to mediate polarization of neurons in mammals and embryos in inv
Autor:
Yoshichika Katsura, Shunsuke Kitajima, Pakorn Kanchanawong, Kiyoshi Tohyama, Chiaki Takahashi, Naoki Watanabe, Shuh Narumiya, Matthew F. Krummel, Dean Thumkeo, Toshimasa Ishizaki, Yukako Nishimura, Takako Hirata
Publikováno v:
Science advances, vol 6, iss 1
Science Advances
Science Advances
The mechanism by which the cytosolic protein Zap70 physically interacts with and phosphorylates its substrate, the transmembrane protein LAT, upon T cell receptor (TCR) stimulation remains largely obscure. In this study, we found that the pharmacolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f35885d443110495f2db9bfcfaad43e
https://escholarship.org/uc/item/3mx556nn
https://escholarship.org/uc/item/3mx556nn
Publikováno v:
Nature Cell Biology. 19:988-995
Cell polarization enables zygotes to acquire spatial asymmetry, which in turn patterns cellular and tissue axes during development. Local modification in the actomyosin cytoskeleton mediates spatial segregation of partitioning-defective (PAR) protein
Autor:
Yukako Nishimura, Shidong Shi, Fang Zhang, Rong Liu, Yasuharu Takagi, Bershadsky, Alexander D., Viasnoff, Virgile, Sellers, James R.
Publikováno v:
Journal of Cell Science; Apr2021, Vol. 134 Issue 8, p1-11, 11p
A mechano-signalling network linking microtubules, myosin IIA filaments and integrin-based adhesions
Autor:
Pakorn Kanchanawong, Meenubharathi Natarajan, Gareth E. Jones, Yukako Nishimura, Nisha Bte Mohd Rafiq, Alexander D. Bershadsky, Zhen Zhang, Sergey V. Plotnikov, Virgile Viasnoff, Visalatchi Thiagarajan, Shidong Shi
Publikováno v:
Nature Materials
Nature Materials, Nature Publishing Group, 2019, 18 (6), pp.638-649. ⟨10.1038/s41563-019-0371-y⟩
Rafiq, N B M, Nishimura, Y, Plotnikov, S V, Thiagarajan, V, Zhang, Z, Shi, S, Natarajan, M, Viasnoff, V, Kanchanawong, P, Jones, G E & Bershadsky, A D 2019, ' A mechano-signalling network linking microtubules, myosin IIA filaments and integrin-based adhesions. ', NATURE MATERIALS, vol. 18, no. 6, pp. 638-649 . https://doi.org/10.1038/s41563-019-0371-y
Nature Materials, Nature Publishing Group, 2019, 18 (6), pp.638-649. ⟨10.1038/s41563-019-0371-y⟩
Rafiq, N B M, Nishimura, Y, Plotnikov, S V, Thiagarajan, V, Zhang, Z, Shi, S, Natarajan, M, Viasnoff, V, Kanchanawong, P, Jones, G E & Bershadsky, A D 2019, ' A mechano-signalling network linking microtubules, myosin IIA filaments and integrin-based adhesions. ', NATURE MATERIALS, vol. 18, no. 6, pp. 638-649 . https://doi.org/10.1038/s41563-019-0371-y
The interrelationship between microtubules and the actin cytoskeleton in mechanoregulation of integrin-mediated adhesions is poorly understood. Here, we show that the effects of microtubules on two major types of cell-matrix adhesion, focal adhesions
Autor:
Nisha Bte Mohd Rafiq, Yukako Nishimura, Sergey V. Plotnikov, Visalatchi Thiagarajan, Zhen Zhang, Meenubharathi Natarajan, Shidong Shi, Virgile Viasnoff, Gareth E. Jones, Pakorn Kanchanawong, Alexander D. Bershadsky
The interrelationship between microtubules and the actin cytoskeleton in mechanoregulation of integrin-mediated adhesions is poorly understood. Here, we show that the effects of microtubules on two major types of cell-matrix adhesions, focal adhesion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22a1025312737d7f0bc579b2deb460c
https://doi.org/10.1101/195495
https://doi.org/10.1101/195495