Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Yuka Takeo"'
Autor:
Chun-Hui Zhang, Elizabeth A. Stone, Maya Deshmukh, Joseph A. Ippolito, Mohammad M. Ghahremanpour, Julian Tirado-Rives, Krasimir A. Spasov, Shuo Zhang, Yuka Takeo, Shalley N. Kudalkar, Zhuobin Liang, Farren Isaacs, Brett Lindenbach, Scott J. Miller, Karen S. Anderson, William L. Jorgensen
Publikováno v:
ACS Central Science, Vol 7, Iss 3, Pp 467-475 (2021)
Externí odkaz:
https://doaj.org/article/21f39d6febba495a8aac30e488fc3ee5
Publikováno v:
Science Advances. 9
During entry, human papillomavirus (HPV) traffics from the cell surface to the endosome and then to the trans-Golgi network (TGN) and Golgi apparatus. HPV must transit across the TGN/Golgi and exit these compartments to reach the nucleus to cause inf
Autor:
Zhuobin Liang, Shalley N. Kudalkar, Krasimir A. Spasov, Julian Tirado-Rives, Scott J. Miller, Shuo Zhang, Karen S. Anderson, Maya Deshmukh, Brett D. Lindenbach, William L. Jorgensen, Joseph A. Ippolito, Farren J. Isaacs, Elizabeth A Stone, Mohammad Mehdi Ghahremanpour, Yuka Takeo, Chun-Hui Zhang
Publikováno v:
ACS Central Science
ACS Central Science, Vol 7, Iss 3, Pp 467-475 (2021)
ACS Central Science, Vol 7, Iss 3, Pp 467-475 (2021)
Starting from our previous finding of 14 known drugs as inhibitors of the main protease (Mpro) of SARS-CoV-2, the virus responsible for COVID-19, we have redesigned the weak hit perampanel to yield multiple noncovalent, nonpeptidic inhibitors with ca