Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Yuka SASAKAWA"'
Autor:
Takashi UMEHARA, Marino OGASAHARA, D.M.V. Supun PREMARATHNE, Yuka SASAKAWA, Yasuo SUMIDA, Masayuki SHIMADA
Publikováno v:
The Journal of Reproduction and Development, Vol 70, Iss 3, Pp 202-206 (2024)
Ovarian fibrosis contributes to age-related ovarian dysfunction. In our previous study, we observed ovarian fibrosis in both obese and aging mice with intracellular lipid droplets in the fibrotic ovaries. Although the importance of mitochondria in ov
Externí odkaz:
https://doaj.org/article/c0aa709f0e764b44aa30ac28870be3a3
Autor:
Liqing Zang, Yasuhito Shimada, Hiroko Nakayama, Izumi Matsuoka, Youngil Kim, Djong-Chi Chu, Lekh Raj Juneja, Rika Tsuruta, Yuka Sasakawa, Junya Kuroyanagi, Norihiro Nishimura
Publikováno v:
Frontiers in Nutrition, Vol 8 (2021)
Globin digest (GD), a bioactive oligopeptide derived from porcine hemoglobin proteins, has been demonstrated to have beneficial effects on improving postprandial hyperlipidemia, hyperglycemia, and liver injury. We previously reported the lipid-loweri
Externí odkaz:
https://doaj.org/article/5dedae1e9cbf46eda4edf483e1a9c3aa
Autor:
Kaori Yamamoto, Fumiko Nakaoka, Lekh Raj Juneja, Michiyo Abe, Mayumi Nakao, Yuka Sasakawa, Jun Kunisawa, Shigetoshi Okumura, Akari Kominami
Publikováno v:
Journal of Food and Nutrition Research. 6:509-512
It has been reported that Glycyrrhiza uralensis (Ural licorice) extract, with the brand name “LICONINE®”, at an intake level of low risk (human equivalent to less than 1 g licorice per day) had anti-obesity and anti-inflammatory effects on high-
Autor:
Hiroko Nakayama, Zang Liqing, Junya Kuroyanagi, Djong-Chi Chu, Lekh Raj Juneja, Izumi Matsuoka, Norihiro Nishimura, Yuka Sasakawa, Yasuhito Shimada, Young Il Kim, Rika Tsuruta
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 94:2-Y
Autor:
Mayumi Nakao, Miki Nakamura, Kaori Yamamoto, Fumiko Nakaoka, Kyoichi Kagawa, Chizuko Fukuhama, Yuka Sasakawa, Akari Kominami, Michiyo Abe
Publikováno v:
Life Sciences. 90:190-199
Aims We investigated the effects of globin digest (GD) and its active ingredient Trp-Thr-Gln-Arg (WTQR) on galactosamine/lipopolysaccharide (GalN/LPS)-induced liver injury in imprinting control region (ICR) mice. Main methods The effects of WTQR and
Autor:
Chunning Tong, Yuka Sasakawa, Chizuko Fukuhama, Kaori Yamamoto, Fumiko Nakaoka, Kyoichi Kagawa, Mayumi Nakao, Miki Nakamura
Publikováno v:
Life Sciences. 86:424-434
Aims Leu-Ser-Glu-Leu (LSEL) is the main active ingredient of globin digest (GD) that has an anti-diabetic effect. Here, we investigated the anti-diabetic effect of LSEL for the first time. Main methods The anti-diabetic effects of GD and LSEL in ICR
Autor:
Naoki Sogo, Seitaro Mutoh, Toshitaka Manda, Yuka Sasakawa, Masahiko Matsuo, Tatsuya Sasakawa, Yoshinori Naoe, Takeshi Inoue
Publikováno v:
Biochemical Pharmacology. 69:603-616
In this study, we detected genes sensitive to an histone deacetylase inhibitor, FK228 [(E)-(1S,4S,10S,21R)-7-[(Z)-ethylidene]-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo-[8,7,6]-tricos-16-ene-3,6,9,19,22-pentanone; FR901228, depsipe
Autor:
Yoshitaka Ohkubo, Yuka Sasakawa, Taro Masunaga, Seitaro Mutoh, Tatsuya Sasakawa, Takashi Fujitsu, Yoshitaka Hirayama
Publikováno v:
Cytokine. 29:67-71
FK506 suppresses activation of T cells; however, it down-regulates E-selectin, ICAM-1 and VCAM-1 expression in inflamed tissues. In this study, we investigated the effect of FK506 on expression of those adhesion molecules on human vascular endothelia
Autor:
Miyuki, Mabuchi, Tadashi, Shimizu, Masahiro, Ueda, Yuka, Sasakawa, Syuhei, Nakao, Yuko, Ueda, Akio, Kawamura, Kazutake, Tsujikawa, Akito, Tanaka
Publikováno v:
In vivo (Athens, Greece). 29(1)
Prostate cancer antigen (PCA)-1/AlkB homologue 3 (ALKBH3) has been identified as a clinically significant factor and siRNA of PCA-1 inhibits DU145 proliferation both in vitro and in vivo. HUHS015 ( 1: ), a previous reported PCA-1 small-molecule inhib
Autor:
Toshitaka Manda, Toshio Goto, Yuka Sasakawa, Masahiko Matsuo, Fusako Nishigaki, Ikuo Kawamura, Sanae Matsumoto, Susumu Tsujimoto, Masamichi Inami, Yoshinori Naoe
Publikováno v:
Cancer Letters. 181:39-45
The effects of FK317 (11-acetyl-8-carbamoyloxymethyl-4-formyl-6-methoxy-14-oxa-1,11-diazatetraacylo[7.4.1.0 2,7 .0 10,2 ]tetradeca-2,4,6-trien-9-yl acetate), a novel anti-cancer agent, and mitomycin C (MMC) on survival time of mice bearing B16BL6 mel