Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Yuka Okusha"'
Autor:
Yuka Okusha, Martin E. Guerrero-Gimenez, Benjamin J. Lang, Thiago J. Borges, Mary A. Stevenson, Andrew W. Truman, Stuart K. Calderwood
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract The dynamic network of chaperone interactions known as the chaperome contributes significantly to the proteotoxic cell response and the malignant phenotype. To bypass the inherent redundancy in the network, we have used a microRNA (mir) appr
Externí odkaz:
https://doaj.org/article/08c5c3ecf3294ec38e46e5dccd87122b
Autor:
Kisho Ono, Chiharu Sogawa, Hotaka Kawai, Manh Tien Tran, Eman A. Taha, Yanyin Lu, May Wathone Oo, Yuka Okusha, Hirohiko Okamura, Soichiro Ibaragi, Masaharu Takigawa, Ken-Ichi Kozaki, Hitoshi Nagatsuka, Akira Sasaki, Kuniaki Okamoto, Stuart K. Calderwood, Takanori Eguchi
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
Evidence has been accumulating to indicate that extracellular vesicles (EVs), including exosomes, released by cancer cells can foster tumour progression. The molecular chaperones – CDC37, HSP90α and HSP90β play key roles in cancer progression inc
Externí odkaz:
https://doaj.org/article/b53c1f3ebc004569af677ed7fa7d9e2a
Autor:
Chiharu Sogawa, Takanori Eguchi, Yuri Namba, Yuka Okusha, Eriko Aoyama, Kazumi Ohyama, Kuniaki Okamoto
Publikováno v:
Cells, Vol 10, Iss 2, p 344 (2021)
Researchers have developed several three-dimensional (3D) culture systems, including spheroids, organoids, and tumoroids with increased properties of cancer stem cells (CSCs), also called cancer-initiating cells (CICs). Drug resistance is a crucial i
Externí odkaz:
https://doaj.org/article/18a3acb009564e61a6c5bca339c5366e
Autor:
Yuka Okusha, Manh Tien Tran, Mami Itagaki, Chiharu Sogawa, Takanori Eguchi, Tatsuo Okui, Tomoko Kadowaki, Eiko Sakai, Takayuki Tsukuba, Kuniaki Okamoto
Publikováno v:
Cells, Vol 9, Iss 11, p 2384 (2020)
Osteoclast differentiation and activity are controlled by two essential cytokines, macrophage colony-stimulating factor (M-CSF) and the receptor activator of nuclear factor-κB ligand (RANKL). Rab11A GTPase, belonging to Rab11 subfamily representing
Externí odkaz:
https://doaj.org/article/5c23f84fbdf541adaeeabcd547361558
Autor:
Takanori Eguchi, Chiharu Sogawa, Kisho Ono, Masaki Matsumoto, Manh Tien Tran, Yuka Okusha, Benjamin J. Lang, Kuniaki Okamoto, Stuart K. Calderwood
Publikováno v:
Cells, Vol 9, Iss 3, p 755 (2020)
Tumor cells exhibit therapeutic stress resistance-associated secretory phenotype involving extracellular vesicles (EVs) such as oncosomes and heat shock proteins (HSPs). Such a secretory phenotype occurs in response to cell stress and cancer therapeu
Externí odkaz:
https://doaj.org/article/4f836b75acc440b19d6fa27048a10563
Autor:
Yuri Namba, Chiharu Sogawa, Yuka Okusha, Hotaka Kawai, Mami Itagaki, Kisho Ono, Jun Murakami, Eriko Aoyama, Kazumi Ohyama, Jun-ichi Asaumi, Masaharu Takigawa, Kuniaki Okamoto, Stuart K. Calderwood, Ken-ichi Kozaki, Takanori Eguchi
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
The ATP-binding cassette transporter G1 (ABCG1) is a cholesterol lipid efflux pump whose role in tumor growth has been largely unknown. Our transcriptomics revealed that ABCG1 was powerfully expressed in rapidly metastatic, aggregative colon cancer c
Externí odkaz:
https://doaj.org/article/ce1ff0e7852740228584faa31fc1baf4
Autor:
Takanori Eguchi, Chiharu Sogawa, Yuka Okusha, Kenta Uchibe, Ryosuke Iinuma, Kisho Ono, Keisuke Nakano, Jun Murakami, Manabu Itoh, Kazuya Arai, Toshifumi Fujiwara, Yuri Namba, Yoshiki Murata, Kazumi Ohyama, Manami Shimomura, Hirohiko Okamura, Masaharu Takigawa, Tetsuya Nakatsura, Ken-Ichi Kozaki, Kuniaki Okamoto, Stuart K Calderwood
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191109 (2018)
Ability to form cellular aggregations such as tumorspheres and spheroids have been used as a morphological marker of malignant cancer cells and in particular cancer stem cells (CSC). However, the common definition of the types of cellular aggregation
Externí odkaz:
https://doaj.org/article/921dd99a06f24871ae74dcd1bd37fa52
Publikováno v:
Cell Stress and Chaperones. 28:167-175
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1369110a579fd7033b5fc087cd3d643e
https://doi.org/10.1007/s12192-023-01326-z
https://doi.org/10.1007/s12192-023-01326-z
Autor:
Yuka Okusha, Benjamin J. Lang, Ayesha Murshid, Thiago J. Borges, Kristina M. Holton, Joanne Clark-Matott, Sachin Doshi, Tsuneya Ikezu, Stuart K. Calderwood
Publikováno v:
Cell Stress and Chaperones. 27:479-483
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d1379851e7e729f536055c97bd22d93
https://doi.org/10.1007/s12192-022-01285-x
https://doi.org/10.1007/s12192-022-01285-x
Autor:
Yunxia Feng, Manh Tien Tran, Yanyin Lu, Kaung Htike, Yuka Okusha, Chiharu Sogawa, Takanori Eguchi, Tomoko Kadowaki, Eiko Sakai, Takayuki Tsukuba, Kuniaki Okamoto
Publikováno v:
Cell Biochemistry and Function. 40:263-277
Accumulating evidence suggests that Rab GTPases representing the largest branch of Ras superfamily have recently emerged as the core factors for the regulation of osteoclastogenesis through modulating vesicular transport amongst specific subcellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c12f2b9a0c0eee6070b8ed8531d2fd3
https://doi.org/10.1002/cbf.3691
https://doi.org/10.1002/cbf.3691