Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yuka Milton"'
Autor:
Volha Liaudanskaya, Nicholas J. Fiore, Yang Zhang, Yuka Milton, Marilyn F. Kelly, Marly Coe, Ariana Barreiro, Victoria K. Rose, Matthew R. Shapiro, Adam S. Mullis, Anna Shevzov-Zebrun, Mathew Blurton-Jones, Michael J. Whalen, Aviva J. Symes, Irene Georgakoudi, Thomas J. F. Nieland, David L. Kaplan
Publikováno v:
Cell Death and Disease, Vol 14, Iss 8, Pp 1-15 (2023)
Abstract Traumatic Brain injury-induced disturbances in mitochondrial fission-and-fusion dynamics have been linked to the onset and propagation of neuroinflammation and neurodegeneration. However, cell-type-specific contributions and crosstalk betwee
Externí odkaz:
https://doaj.org/article/c2e87a4a96b24b3fae0b37195524c50d
Autor:
Volha Liaudanskaya, Nicholas J Fiore, Yang Zhang, Yuka Milton, Marilyn F Kelly, Marly Coe, Ariana Barreiro, Victoria K Rose, Matthew R Shapiro, Adam S Mullis, Anna Shevzov-Zebrun, Mathew Blurton-Jones, Michael J Whalen, Aviva J Symes, Irene Georgakoudi, Thomas JF Nieland, David L Kaplan
Traumatic Brain injury-induced disturbances in mitochondrial fission-and-fusion dynamics have been linked to the onset and propagation of neuroinflammation and neurodegeneration. However, cell-type-specific contributions and crosstalk between neurons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14d1e0046c1afe810c2bf75a6aeee22e
https://doi.org/10.1101/2022.09.23.509276
https://doi.org/10.1101/2022.09.23.509276
Autor:
Anna Herland, Ben Swenor, Daniel Levner, Olivier Y.F. Henry, Sasan Jalili-Firoozinezhad, Angeliki Chalkiadaki, Henry Sanchez, Andrzej Przekwas, Sauveur S. F. Jeanty, Rachelle Prantil-Baun, Josiah Sliz, Youngjae Choe, Kyung-Jin Jang, Moran Yadid, Susan Marquez, Chris Hinojosa, Thomas C. Ferrante, Blakely B. O'Connor, Tiama Hamkins-Indik, Rachel Fleming, Stephanie Dauth, Janna Nawroth, Morgan Burt, Ben M. Maoz, David B. Chou, Aaron Delahanty, John P. Ferrier, Anthony Bahinski, Jose Fernandez-Alcon, Bret Nestor, Guy Robert Thompson, Lian Leng, Robert Mannix, Michael J. Cronce, Yuka Milton, Mahadevabharath R. Somayaji, Alexandra Sontheimer-Phelps, Tae-Eun Park, Miles Ingram, Edward A. FitzGerald, Debarun Das, Ville J. Kujala, Josue A. Goss, George J. Touloumes, Toni Divic, Carlos F. Ng, Oren Levy, Zachary Tranchemontagne, Elizabeth Calamari, Geraldine A. Hamilton, Alexander Cho, Thomas Grevesse, Norman Wen, Tessa Huffstater, Donald E. Ingber, Kevin Kit Parker, Richard M. Novak
Publikováno v:
Nature Biomedical Engineering. 4:407-420
Organ chips can recapitulate organ-level (patho)physiology, yet pharmacokinetic and pharmacodynamic analyses require multi-organ systems linked by vascular perfusion. Here, we describe an 'interrogator' that employs liquid-handling robotics, custom s
Autor:
David B. Chou, Rachelle Prantil-Baun, Ben Swenor, Sasan Jalili-Firoozinezhad, Andrzej Przekwas, Susan Marquez, Tessa Huffstater, Donald E. Ingber, Ben M. Maoz, Anna Herland, Michael J. Cronce, Yuka Milton, Angeliki Chalkiadaki, Miles Ingram, Mahadevabharath R. Somayaji, Alexandra Sontheimer-Phelps, Oren Levy, Sauveur S. F. Jeanty, Richard M. Novak, Aaron Delahanty, Kevin Kit Parker, Debarun Das
Publikováno v:
Nature Biomedical Engineering. 4:421-436
Analyses of drug pharmacokinetics (PKs) and pharmacodynamics (PDs) performed in animals are often not predictive of drug PKs and PDs in humans, and in vitro PK and PD modelling does not provide quantitative PK parameters. Here, we show that physiolog
Autor:
Petar Pop-Damkov, Rhiannon David, Arianna Rech, Lucy R. O’Sullivan, Susan Marquez, Brooke A. Furlong, Douglas Ferguson, Kasiani C. Myers, Amanda Jiang, Liliana Moreira Teixeira, Oren Levy, Youngjae Choe, Özge Vargel Bölükbaşı, David B. Chou, Richard M. Novak, Olga K. Weinberg, Carl D. Novina, Robert P. Hasserjian, Lorna Ewart, Yuka Milton, Cailin E. Joyce, Viktoras Frismantas, Elizabeth Calamari, Sasan Jalili-Firoozinezhad, Rachelle Prantil-Baun, Donald E. Ingber, Alexander MacDonald, Akiko Shimamura, Carlos F. Ng
Publikováno v:
Nature biomedical engineering
The inaccessibility of living bone marrow (BM) hampers the study of its pathophysiology under myelotoxic stress induced by drugs, radiation or genetic mutations. Here, we show that a vascularized human BM-on-a-chip (BM chip) supports the differentiat
Autor:
Milad Rezvani, Kyle Lewis, Kentaro Iwasawa, Yuqi Cai, Yuka Milton, Masaki Kimura, RanRan Zhang, Praneet Chaturvedi, Takanori Takebe
Publikováno v:
Journal of Hepatology. 77:S673
Autor:
Deepak Bhere, Oren Levy, Nabeel Nissar, Erika M. J. Siren, Yuka Milton, Martina Heinelt, Mohanad Fallatah, Khalid Shah, Michael De Biasio, Abdulaziz Almalik, Brock Reeve, Jeffrey M. Karp, Ali H. Alhasan, Rui Kuai, Reza Abdi, Meshael Alturki
Publikováno v:
Science Advances
To realize the potential of MSCs, bioengineering is needed to boost potency and control heterogeneity.
More than 1050 clinical trials are registered at FDA.gov that explore multipotent mesenchymal stromal cells (MSCs) for nearly every clinical a
More than 1050 clinical trials are registered at FDA.gov that explore multipotent mesenchymal stromal cells (MSCs) for nearly every clinical a
Autor:
William M. Siders, Qingping Wang, Rui Kuai, Jonathan Rothblatt, Francisco J. Quintana, Juliet Musabeyezu, Yuka Milton, Heidi Kuang, Manal Alaamery, Ivan D. Mascanfroni, Martina Heinelt, Veit Rothhammer, Ali H. Alhasan, Haoyue Lan, Jessica E. Kenison, Marie-Christine Multon, Jeffrey M. Karp, Helia Safaee, Christelle Perrault, Oren Levy, Michael De Biasio, Tahir Majid, Salam Massadeh, Ada Yeste, Zhixiang Tong
Publikováno v:
J Mol Med (Berl)
Mesenchymal stem cells (MSCs) are promising candidates for the development of cell-based drug delivery systems for autoimmune inflammatory diseases, such as multiple sclerosis (MS). Here, we investigated the effect of Ro-31-8425, an ATP-competitive k
Autor:
Anna, Herland, Ben M, Maoz, Debarun, Das, Mahadevabharath R, Somayaji, Rachelle, Prantil-Baun, Richard, Novak, Michael, Cronce, Tessa, Huffstater, Sauveur S F, Jeanty, Miles, Ingram, Angeliki, Chalkiadaki, David, Benson Chou, Susan, Marquez, Aaron, Delahanty, Sasan, Jalili-Firoozinezhad, Yuka, Milton, Alexandra, Sontheimer-Phelps, Ben, Swenor, Oren, Levy, Kevin K, Parker, Andrzej, Przekwas, Donald E, Ingber
Publikováno v:
Nature biomedical engineering. 4(4)
Analyses of drug pharmacokinetics (PKs) and pharmacodynamics (PDs) performed in animals are often not predictive of drug PKs and PDs in humans, and in vitro PK and PD modelling does not provide quantitative PK parameters. Here, we show that physiolog
Autor:
Ben M. Maoz, Sasan Jalili-Firoozinezhad, Andrzej Przekwas, Carlos F. Ng, Alexander Cho, Anna Herland, Jose Fernandez-Alcon, Daniel Levner, Olivier Y.F. Henry, Janna Nawroth, Blakely B. O'Connor, Debarun Das, David B. Chou, Kevin Kit Parker, Anthony Bahinski, Morgan Burt, Ville J. Kujala, Susan Clauson, Mahadevabharath R. Somayaji, Thomas C. Ferrante, Ben Swenor, Henry Sanchez, Lian Leng, Tessa Huffstater, Angeliki Chalkiadaki, Miles Ingram, Donald E. Ingber, Tiama Hamkins-Indik, Norman Wen, Rachelle Prantil-Baun, Youngjae Choe, Josiah Sliz, Zachary Tranchemontagne, Bret Nestor, George J. Touloumes, Rachel Fleming, Guy Robert Thompson, Alexandra Sontheimer-Phelps, Josue A. Goss, Oren Levy, Toni Divic, Elizabeth Calamari, Sauveur S. F. Jeanty, Kyung-Jin Jang, Michael J. Cronce, Yuka Milton, Richard M. Novak, Geraldine A. Hamilton, Thomas Grevesse, Chris Hinojosa, Moran Yadid, Stephanie Dauth, John P. Ferrier, Tae-Eun Park, Robert Mannix, Edward A. FitzGerald, Aaron Delahanty
Publikováno v:
Nat Biomed Eng
Here we describe of an ‘Interrogator’ instrument that uses liquid-handling robotics, a custom software package, and an integrated mobile microscope to enable automated culture, perfusion, medium addition, fluidic linking, sample collection, andin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91904c828996f1d91cb14b8c52e98514
https://doi.org/10.1101/569541
https://doi.org/10.1101/569541