Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yuka Hiraoka"'
Autor:
Yoko Nakajima, Shuhei Osaka, Tadahaya Mizuno, Katsuyuki Yokoi, Satoshi Nakano, Saeko Hirai, Yuka Hiraoka, Yoshiki Miura, Mitsuyoshi Suzuki, Hiroyuki Kusuhara, Hisamitsu Hayashi
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 29, Iss , Pp 100799- (2021)
Urea cycle disorders (UCDs), inborn errors of hepatocyte metabolism, cause hyperammonemia and lead to neurocognitive deficits, coma, and even death. Sodium 4-phenylbutyrate (NaPB), a standard adjunctive therapy for UCDs, generates an alternative path
Externí odkaz:
https://doaj.org/article/bd2ef431f75b4e2fb94027b6644be228
Autor:
Hiroyuki Kusuhara, Mitsuyoshi Suzuki, Yoshiki Miura, Shuhei Osaka, Yusuke Sabu, Hisamitsu Hayashi, Ayumu Mizutani, Satoshi Nakano, Kei Minowa, Yuka Hiraoka, Tadahaya Mizuno, Saeko Hirai, Toshiaki Shimizu
Publikováno v:
Molecular Genetics and Metabolism. 132:220-226
Urea cycle disorders (UCDs), inborn errors of hepatocyte metabolism, result in the systemic accumulation of ammonia to toxic levels. Sodium 4-phenylbutyrate (NaPB), a standard therapy for UCDs for over 20 years, generates an alternative pathway of ni
Publikováno v:
Juntendo Medical Journal. 64:86-90
Autor:
Reiko Mineki, Norihiko Furuya, Takashi Ueno, Tsutomu Fujimura, Dong-Mei Zheng, Zehua Bian, Yuka Hiraoka, Juan Alejandro Oliva Trejo, Katsuyuki Takahashi, Shin-ichi Ikeda, Hikari Taka, Mitsue Takeda-Ezaki, Masaaki Komatsu, Junji Ezaki
Publikováno v:
Biochemical and biophysical research communications. 456(1)
It has been well established that a starvation-induced decrease in insulin/IGF-I and serum amino acids effectively suppresses the mammalian target of rapamycin (mTor) signaling to induce autophagy, which is a major degradative cellular pathway in ske
Autor:
Norihiro Tada, Takashi Ueno, Hikari Taka, Yuka Hiraoka, Katsuyuki Takahashi, Tsutomu Fujimura, Dong Mei Zheng, Junji Ezaki, Kenji Takehana, Junichi Iwata, Mitsue Takeda-Ezaki, Mitsutaka Yoshida, Masaaki Komatsu, Isei Tanida, Norihiko Furuya, Naomi Matsumoto, Keiji Tanaka, Eiki Kominami
Publikováno v:
Autophagy. 7(7)
Both anabolism and catabolism of the amino acids released by starvation-induced autophagy are essential for cell survival, but their actual metabolic contributions in adult animals are poorly understood. Herein, we report that, in mice, liver autopha