Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yuka Hiramatsu"'
Autor:
Takahiro Ito, Mikio Yoshida, Tomomi Aida, Itaru Kushima, Yuka Hiramatsu, Maiko Ono, Akira Yoshimi, Kohichi Tanaka, Norio Ozaki, Yukihiro Noda
Publikováno v:
Journal of Neurochemistry. 165:211-229
Autor:
Jayan D.M. Senevirathna, Ryo Yonezawa, Taiki Saka, Yuka Hiramatsu, Ashley Rinka Smith, Yoji Igarashi, Kazutoshi Yoshitake, Shigeharu Kinoshita, Noriko Funasaka, Shuichi Asakawa
Publikováno v:
Journal of Genomics. 11:9-13
Autor:
Norio Ozaki, Takuya Yoshigai, Akira Yoshimi, Takayoshi Mamiya, Yuka Hiramatsu, Takahiro Ito, Ayaki Takahashi, Akihiro Mouri, Yukihiro Noda
Publikováno v:
Neuroscience research. 171
Stress vulnerability and pathogenic mechanisms in stress-related disorders are strongly associated with the functions of serotonin transporter (SERT). SERT phosphorylation induces a reduction of the serotonin (5-HT, 5-hydroxytryptamine) transport pro
Autor:
Akihiro Mouri, Yukihiro Noda, Norio Ozaki, Takayoshi Mamiya, Mizuki Uchida, Takahiro Ito, Akira Yoshimi, Yuka Hiramatsu
Publikováno v:
Neurochemistry International. 140:104826
Selective serotonin reuptake inhibitors are the first-line antidepressants for treating major depressive and post-traumatic stress disorders. These inhibitors directly bind to the serotonin transporter (SERT). Protein kinase C (PKC) is a key regulato
Autor:
Toshito Nakagawa, Kazumi Ohkubo, Akira Okazaki, Masaki Ishigai, Yuka Hiramatsu, Yoshihiko Ishitani
Publikováno v:
Drug Metabolism and Pharmacokinetics. 10:625-636
The metabolism of 14C labeled Q-35 [(±)-1-cyclopropyl-6-fluoro-1, 4-dihydro-8-methoxy-7 (3-methylaminopiperidin-1-yl)-4-oxoquinoline-3-carboxylic acid], a new fluoroquinolone antimicrobial agent, was studied in rats and dogs.1. Two metabolites were
Publikováno v:
Drug Metabolism and Pharmacokinetics. 8:1213-1218
To evaluate the role of the kidney in the elimination of rG·CSF, the pharmackinetics of rG·CSF was studied in rats upon removal of one (1/2-nephrectomized rat) or of two kidneys (nephrectomized rat). Plasma concentrations of rG·CSF were measured b
Autor:
Haruki Kinoshita, Yuka Hiramatsu, Naohiko Hayakawa, Ken Okano, Akira Okazaki, Jun Amano, Motohiro Kato
Publikováno v:
Drug Metabolism and Pharmacokinetics. 8:1199-1212
The metabolites of rG·CSF present in the serum were investigated in rats after intravenous administration of 125I-rG·CSF at the dose of 10μg/kg, or nonlabeled-rG·CSF at the dose of 100-400μg/kg. 1. Using gel filtration on the Superose 12 column,
Publikováno v:
Drug Metabolism and Pharmacokinetics. 8:1181-1190
rG·CSF is a recombinant human granulo cyte colony-stimulating factor (rhG-CSF) produced in CHO cells. rG·CSF is a glycoprotein which has one O-linked sugar chain. We have studied the role of this sugar chain on the disposition of rG·CSF using enzy
Publikováno v:
Drug Metabolism and Pharmacokinetics. 8:1191-1197
We have studied the effect of sialic acid in rG·CSF on the disposition of rG·CSF using monosialo-rG·CSF and disialo-rG·CSF. 1. Monosialo-rG·CSF and disialo-rG·CSF were administered to male rats at the dose of 50μg/kg intravenously and subcutan
Autor:
Senevirathna, Jayan D. M.1,2 duminda@uwu.ac.lk, Ryo Yonezawa1, Taiki Saka1, Yuka Hiramatsu1, Smith, Ashley Rinka1, Yoji Igarashi3, Kazutoshi Yoshitake1, Shigeharu Kinoshita1, Noriko Funasaka4, Shuichi Asakawa1 asakawa@g.ecc.u-tokyo.ac.jp
Publikováno v:
Journal of Genomics. 2023, Vol. 11, p9-13. 5p.