Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Yuka Harata-Lee"'
Autor:
Yuka Harata-Lee, Zhipeng Qu, Emma Bateman, Xi Xiao, Marianne D. Keller, Joanne Bowen, Wei Wang, David L. Adelson
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Mucositis, or damage/injury to mucous membranes of the alimentary, respiratory, or genitourinary tract, is the major side effect associated with anticancer radiotherapies. Because there is no effective treatment for mucositis at present, this is a pa
Externí odkaz:
https://doaj.org/article/61510518b4f6425fa70171751d32bac8
Autor:
Cherry L. Wainwright, Mauro M. Teixeira, David L. Adelson, Eric J. Buenz, Bruno David, Keith B. Glaser, Yuka Harata-Lee, Melanie-Jayne R. Howes, Angelo A. Izzo, Pasquale Maffia, Alejandro M.S. Mayer, Claire Mazars, David J. Newman, Eimear Nic Lughadha, Adriano M.C. Pimenta, John A.A. Parra, Zhipeng Qu, Hanyuan Shen, Michael Spedding, Jean-Luc Wolfender
Publikováno v:
Pharmacological Research, Vol 180, Iss , Pp 106207- (2022)
Externí odkaz:
https://doaj.org/article/b215426536d141999cb70e91b0a202d1
Autor:
Cherry L. Wainwright, Mauro M. Teixeira, David L. Adelson, Fernão C. Braga, Eric J. Buenz, Priscilla R.V. Campana, Bruno David, Keith B. Glaser, Yuka Harata-Lee, Melanie-Jayne R. Howes, Angelo A. Izzo, Pasquale Maffia, Alejandro M.S. Mayer, Claire Mazars, David J. Newman, Eimear Nic Lughadha, Rodrigo M. Pádua, Adriano M.C. Pimenta, John A.A. Parra, Zhipeng Qu, Hanyuan Shen, Michael Spedding, Jean-Luc Wolfender
Publikováno v:
Pharmacological Research, Vol 177, Iss , Pp 106076- (2022)
Drug discovery from natural sources is going through a renaissance, having spent many decades in the shadow of synthetic molecule drug discovery, despite the fact that natural product-derived compounds occupy a much greater chemical space than those
Externí odkaz:
https://doaj.org/article/7548a631600c45a6b94850aa79d2813e
Autor:
Jian Cui, Zhipeng Qu, Yuka Harata-Lee, Thazin Nwe Aung, Hanyuan Shen, Wei Wang, David L. Adelson
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background In this report we examine candidate pathways perturbed by Compound Kushen Injection (CKI), a Traditional Chinese Medicine (TCM) that we have previously shown to alter the gene expression patterns of multiple pathways and induce ap
Externí odkaz:
https://doaj.org/article/5b7dd2435c8d4a0587698ef071efc10a
Autor:
Jian Cui, Zhipeng Qu, Yuka Harata-Lee, Hanyuan Shen, Thazin Nwe Aung, Wei Wang, R Daniel Kortschak, David L Adelson
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236395 (2020)
Traditional Chinese Medicine (TCM) preparations are often extracts of single or multiple herbs containing hundreds of compounds, and hence it has been difficult to study their mechanisms of action. Compound Kushen Injection (CKI) is a complex mixture
Externí odkaz:
https://doaj.org/article/a87d91825f444080a3cee69f1c2b78b0
Autor:
Jue Zhang, Zhipeng Qu, Hong Yao, Lingling Sun, Yuka Harata-Lee, Jian Cui, Thazin Nwe Aung, Xiaomin Liu, Rongli You, Wei Wang, Lina Hai, David L. Adelson, Lizhu Lin
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 118, Iss , Pp - (2019)
Gefitinib is one of commonly used first-line treatment options for patients with positive EGFR mutation in non-small cell lung cancer (NSCLC). However, most patients with gefitinib treatment relapse over time due to the loss of drug sensitivity. Comp
Externí odkaz:
https://doaj.org/article/bc58fe30308344aaa5fabc85ea0fde1d
Autor:
Hanyuan Shen, Zhipeng Qu, Yuka Harata-Lee, Thazin Nwe Aung, Jian Cui, Wei Wang, R. Daniel Kortschak, David L. Adelson
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Herbal compatibility is the knowledge of which herbs to combine in traditional Chinese medicine (TCM) formulations. The lack of understanding of herbal compatibility is one of the key problems for the application and popularization of TCM in western
Externí odkaz:
https://doaj.org/article/51cb6f8a9f2a4f6db1ab958041cfd0f5
Autor:
Saeed Nourmohammadi, Thazin Nwe Aung, Jian Cui, Jinxin V. Pei, Michael Lucio De Ieso, Yuka Harata-Lee, Zhipeng Qu, David L. Adelson, Andrea J. Yool
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Traditional Chinese Medicines are promising sources of new agents for controlling cancer metastasis. Compound Kushen Injection (CKI), prepared from medicinal plants Sophora flavescens and Heterosmilax chinensis, disrupts cell cycle and induces apopto
Externí odkaz:
https://doaj.org/article/67de71472e354ecca63533fff8659feb
Autor:
Yuka Harata-Lee, Jian Cui, R. Daniel Kortschak, Wei Wang, Thazin Nwe Aung, David L. Adelson, Zhipeng Qu, Hanyuan Shen
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Drug-drug interactions (DDIs), especially with herbal medicines, are complex, making it difficult to identify potential molecular mechanisms and targets. We introduce a workflow to carry out DDI research using transcriptome analysis and interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff290addd552323680f98324ebfa99c
http://link.springer.com/article/10.1038/s41598-019-52375-3
http://link.springer.com/article/10.1038/s41598-019-52375-3
Autor:
Kortschak Rd, Saeed Nourmohammadi, Thazin Nwe Aung, W. Wei, Tara L. Pukala, Zhipeng Qu, Hanyuan Shen, Jian Cui, David L. Adelson, Yuka Harata-Lee, Hong Du, Andrea J. Yool
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports
Scientific Reports
We used computational and experimental biology approaches to identify candidate mechanisms of action of aTraditional Chinese Medicine, Compound Kushen Injection (CKI), in a breast cancer cell line (MDA-MB-231). Because CKI is a complex mixture of pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e192bc5215ac961b3c1e970dad57f7a1
https://doaj.org/article/b912d9a8335549f295a7eb338858c86e
https://doaj.org/article/b912d9a8335549f295a7eb338858c86e