Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Yuk-Man Leung"'
Publikováno v:
Chinese Journal of Physiology, Vol 65, Iss 6, Pp 277-281 (2022)
Ca2+-sensing receptors (CaSRs) are G protein-coupled receptors activated by elevated concentrations of extracellular Ca2+. In our previous works, we showed protein and functional expression of CaSR in mouse cerebral endothelial cell (EC) (bEND.3); th
Externí odkaz:
https://doaj.org/article/985b0353163d4d7cb7205bf4f2458ac2
Autor:
Iat-Lon Leong, Tien-Yao Tsai, Lian-Ru Shiao, Yu-Mei Zhang, Kar-Lok Wong, Paul Chan, Yuk-Man Leung
Publikováno v:
Chinese Journal of Physiology, Vol 64, Iss 2, Pp 80-87 (2021)
Ca2+-sensing receptors (CaSR), activated by elevated concentrations of extracellular Ca2+, have been known to regulate functions of thyroid cells, neurons, and endothelial cells (EC). In this report, we studied CaSR-mediated Ca2+ influx in mouse cere
Externí odkaz:
https://doaj.org/article/848f9d4c1c364e1992fe9193cd3f1109
Autor:
Cing-Yu Chen, Cheng-Hsun Wu, King-Chuen Wu, Lian-Ru Shiao, Chin-Min Chuang, Yuk-Man Leung, Louis W C Chow
Publikováno v:
Chinese Journal of Physiology, Vol 64, Iss 4, Pp 202-209 (2021)
Gamma-linolenic acid (GLA), a natural fatty acid obtained from oils of various vegetables and seeds, has been demonstrated as an anticancer agent. In this work, we investigated the anticancer effects of GLA on breast cancer BT-474 cells. GLA at 30 μ
Externí odkaz:
https://doaj.org/article/5a55c058ae314ae9ae0727b140c2d0c2
Autor:
Kun-Feng Tsai, Chen-Jung Shen, Chi-Wai Cheung, Tzong-Luen Wang, Louis W. C. Chow, Yuk-Man Leung, Kar-Lok Wong
Publikováno v:
Chinese Journal of Physiology, Vol 64, Iss 6, Pp 289-297 (2021)
Palmitic acid (PA) is a saturated free fatty acid which, when being excessive, accounts for lipotoxicity. Using human lung A549 cells as a model for lung alveolar type 2 epithelial cells, we found that challenge of A549 cells with PA resulted in apop
Externí odkaz:
https://doaj.org/article/ee6e6b3fc25541dca2230033d8c2a4a3
Publikováno v:
Journal of Functional Foods, Vol 86, Iss , Pp 104676- (2021)
Endothelium injury caused by reactive oxygen species (ROS) plays a critical role in the pathogenesis of cardiovascular disorders. Paeoniflorin (PF) has shown good antioxidant properties. The present study investigated the effect of PF on oxidative da
Externí odkaz:
https://doaj.org/article/b7c435443fbb4e8f92ac2f335ad15fa7
Autor:
Hung-Hsing Chao, Po-Yuan Chen, Wen-Rui Hao, Wei-Ping Chiang, Tzu-Hurng Cheng, Shih-Hurng Loh, Yuk-Man Leung, Ju-Chi Liu, Jin-Jer Chen, Li-Chin Sung
Publikováno v:
Journal of Biomedical Science, Vol 24, Iss 1, Pp 1-12 (2017)
Abstract Background This study investigated whether lipopolysaccharide (LPS) increase protease-activated receptor-2 (PAR-2) expression and enhance the association between PAR-2 expression and chemokine production in human vascular endothelial cells (
Externí odkaz:
https://doaj.org/article/0afef62cbd6443a1b16d7dc9135b7732
Autor:
Tien‐Yao Tsai, Cing‐Yu Chen, Lian‐Ru Shiao, Ting‐Tsz Ou, Cheng‐Hsun Wu, Yuk‐Man Leung, Louis W. C. Chow
Publikováno v:
Fundamental & Clinical Pharmacology. 37:253-262
Publikováno v:
The Chinese journal of physiology. 65(6)
Ca
Publikováno v:
Life sciences. 308
Lung type 2 alveolar cells, by secreting surfactant to lower surface tension, contribute to enhance lung compliance. Stretching, as a result of lung expansion, triggers type 1 alveolar cell to release ATP, which in turn stimulates CaCaCaDifferent mod
Autor:
Kar-Lok Wong, Paul Chan, Tien-Yao Tsai, Yu Mei Zhang, Yuk-Man Leung, Iat-Lon Leong, Lian-Ru Shiao
Publikováno v:
Chinese Journal of Physiology, Vol 64, Iss 2, Pp 80-87 (2021)
Ca2+-sensing receptors (CaSR), activated by elevated concentrations of extracellular Ca2+, have been known to regulate functions of thyroid cells, neurons, and endothelial cells (EC). In this report, we studied CaSR-mediated Ca2+ influx in mouse cere