Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yujun Pei"'
Autor:
Hao Li, Yu Du, Kaiwen Cheng, Yuxi Chen, Ling Wei, Yujun Pei, Xiaoyu Wang, Lan Wang, Ye Zhang, Xiaoxin Hu, Yi Lu, Xiangjia Zhu
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract High myopia (HM) is a leading cause of blindness worldwide with currently no effective interventions available. A major hurdle lies in its often isolated perception as a purely ocular morbidity, disregarding potential systemic implications.
Externí odkaz:
https://doaj.org/article/c847bf27caee488993beff47b043798c
Publikováno v:
Cells, Vol 13, Iss 19, p 1635 (2024)
Brain endothelial cells (ECs) are essential elements of the blood–brain barrier (BBB), maintaining its integrity through both paracellular junctions and transcellular transport systems. Myosin IIA, a multifunctional protein, plays a significant rol
Externí odkaz:
https://doaj.org/article/bc8dc71f8a7644a4aae0df625afab022
Autor:
Yujun Pei, Zheng Xiang, Kun Wen, Chloe Ran Tu, Xiwei Wang, Yanmei Zhang, Xiaofeng Mu, Yinping Liu, Wenwei Tu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Although γδ-T cell-based tumor immunotherapy using phosphoantigens to boost γδ-T cell immunity has shown success in some cancer patients, the clinical application is limited due to the rapid exhaustion of Vγ9Vδ2-T cells caused by repetitive sti
Externí odkaz:
https://doaj.org/article/065a10626eab4383a8760828b273ddae
Publikováno v:
PLoS Pathogens, Vol 14, Iss 11, p e1007440 (2018)
CD4+ T cells play predominant roles in protective immunity against blood-stage Plasmodium infection, both for IFN-γ-dependent effector mechanisms and providing B cell helper signals. Neddylation, an ubiquitination-like process triggered by covalent
Externí odkaz:
https://doaj.org/article/3978f47a84f84285ae702514cdac6824
Autor:
Guihua Qiu, Jian Liu, Qianqian Cheng, Qingyang Wang, Zhaofei Jing, Yujun Pei, Min Zhao, Jing Wang, Jessie Yanxiang Guo, Jiyan Zhang
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Autophagy plays a central role in maintaining T cell homeostasis. Our previous study has shown that hepatocyte-specific deficiency of receptor for activated C kinase 1 (RACK1) leads to lipid accumulation in the liver, accompanied by impaired autophag
Externí odkaz:
https://doaj.org/article/14113738b44945f3b61533ce50d2fa10
Autor:
Yujun Pei, Jingyang Wang, Jiyan Zhang, Xueying Zhang, Min Zhao, Xiao Yang, Jian Liu, Beifen Shen, Junxia Cao
Publikováno v:
Theranostics
Targeting cancer stem cells (CSCs) has been proposed as a new strategy to eradicate malignancies, including hepatocellular carcinoma (HCC). However, the mechanisms by which CSCs sustain their self-renewal and chemoresistance remain elusive. Nanog is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::605895aca2745238acd6d66a8819aafc
http://europepmc.org/articles/PMC6376462
http://europepmc.org/articles/PMC6376462
Autor:
Zheng Xiang, Xiwei Wang, Kun Wen, Yinping Liu, Xiaofeng Mu, Wenwei Tu, Yujun Pei, Chunyu Huang, Liyan Wen
Publikováno v:
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-10 (2020)
Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-10 (2020)
Influenza epidemics and pandemics are constant threats to global public health. Although strategies including vaccines and antiviral drugs have achieved great advances in controlling influenza virus infection, the efficacy of these strategies is limi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e8411555d02870166b17bbe9a4f9bda
https://pubmed.ncbi.nlm.nih.gov/32488072
https://pubmed.ncbi.nlm.nih.gov/32488072
Publikováno v:
International Journal of Peptide Research and Therapeutics. 24:225-233
A combination of computation techniques and peptide mutants have been used to determine the binding site and amino acid residues on the inhibitor peptide that are critical for binding to Mitogen-activated protein kinase 14 (p38α). In our previous re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbdf539dcc0c5e35ba09f369525ffa91
https://doi.org/10.1007/s10989-017-9607-3
https://doi.org/10.1007/s10989-017-9607-3
Autor:
Wenwei Tu, Haiming Wei, Pamela Pui Wah Lee, Yujun Pei, Zheng Xiang, Yu-Lung Lau, Hui Zhi, Xia Wang, Godfrey Chi-Fung Chan, Xiwei Wang, Irene Oi-Lin Ng, Wilfred Hing Sang Wong, Yinping Liu, Chunyu Huang
Publikováno v:
Science translational medicine. 12(563)
Treatment of life-threatening Epstein-Barr virus (EBV)-associated tumors remains a great challenge, especially for patients with relapsed or refractory disease. Here, we found that exosomes derived from phosphoantigen-expanded Vδ2-T cells (Vδ2-T-Ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf3e114682d4fecc945252e27018e637
https://pubmed.ncbi.nlm.nih.gov/32998970
https://pubmed.ncbi.nlm.nih.gov/32998970
Autor:
Xin Li, Jing Wang, Yujun Pei, Lu Guo, Huanling Cao, Beifen Shen, Qingyang Wang, Jing Xie, Jiyan Zhang, Guihua Qiu, Huifang Wu, Hu Chen, Jian Liu, Lei Hua, Kun Han, Suoqin Tang, Zhaofei Jing, Jiayang Jin, Jun Zhang
Publikováno v:
Leukemialymphoma. 59(5)
All-trans retinoic acid (ATRA) has demonstrated notable success in the treatment of acute promyelocytic leukemia (APL) by inducing granulocytic differentiation. The underlying mechanisms of ATRA therapeutic effects have not been entirely clarified. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18335280eecb4a13df126a7801604695
https://pubmed.ncbi.nlm.nih.gov/28849722
https://pubmed.ncbi.nlm.nih.gov/28849722