Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yujiro Shidara"'
Autor:
Shigeo Ohta, Hideaki Oda, Giovanni Manfredi, Jennifer Q. Kwong, Kazutoshi Nakano, Takashi Kanamori, Kumi Yamagata, Yujiro Shidara
Supplementary Figure 1 from Positive Contribution of Pathogenic Mutations in the Mitochondrial Genome to the Promotion of Cancer by Prevention from Apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e301e0e0397b47faec4933326591907
https://doi.org/10.1158/0008-5472.22364387
https://doi.org/10.1158/0008-5472.22364387
Autor:
Shigeo Ohta, Hideaki Oda, Giovanni Manfredi, Jennifer Q. Kwong, Kazutoshi Nakano, Takashi Kanamori, Kumi Yamagata, Yujiro Shidara
The role of mitochondrial dysfunction in cancer has been a subject of great interest and much ongoing investigation. Although most cancer cells harbor somatic mutations in mitochondrial DNA (mtDNA), the question of whether such mutations contribute t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a70c6e1882c7ca42cfe5e640accdb68
https://doi.org/10.1158/0008-5472.c.6494165
https://doi.org/10.1158/0008-5472.c.6494165
Autor:
Yujiro Shidara, Peter J. Hollenbeck
Publikováno v:
The Journal of Neuroscience. 30:11369-11378
Friedreich ataxia, a neurodegenerative disorder resulting from frataxin deficiency, is thought to involve progressive cellular damage from oxidative stress. InDrosophilalarvae with reduced frataxin expression (DfhIR), we evaluated possible mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da3a221b0bd7cad64066f2c02c727dc8
https://doi.org/10.1523/jneurosci.0529-10.2010
https://doi.org/10.1523/jneurosci.0529-10.2010
Autor:
Satoshi Mizutani, Yasuyuki Miyato, Shigeo Ohta, Takashi Tajiri, Sadamitsu Asoh, Yujiro Shidara, Akira Tokunaga
Publikováno v:
Cancer Science. 100:1680-1687
The majority of cancer cells harbor homoplasmic somatic mutations in the mitochondrial genome. We show here that mutations in mitochondrial DNA (mtDNA) are responsible for anticancer drug tolerance. We constructed several trans-mitochondrial hybrids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0674ee8c939595d1723b8cc51d15ba0c
https://doi.org/10.1111/j.1349-7006.2009.01238.x
https://doi.org/10.1111/j.1349-7006.2009.01238.x
Autor:
Shigeo Ohta, Misao Suzuki, Yukichi Moriyama, Takashi Mori, Shinya Nagai, Yasuhiro Kobayashi, Sadamitsu Asoh, Yujiro Shidara
Publikováno v:
Hepatology Research. 37:133-142
Aim: Apoptosis is involved in hepatic ischemia/reperfusion injury. The protein FNK, constructed from an anti-apoptotic protein Bcl-xL, exhibits the stronger anticell death activity. We evaluated the effect of FNK on apoptosis after hepatic ischemia a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::732b1083ab053725b1abb6d2a7497916
https://doi.org/10.1111/j.1872-034x.2007.00022.x
https://doi.org/10.1111/j.1872-034x.2007.00022.x
Autor:
Yu-ichi Goto, Shigeo Ohta, Yujiro Shidara, Yuri Mukai, Yoshitomo Ishibashi, Kae Munakata, Hideaki Oda, Naomi Nakashima-Kamimura, Sadamitsu Asoh
Publikováno v:
Journal of Cell Science. 118:5357-5367
To investigate the regulatory system in mitochondrial biogenesis involving crosstalk between the mitochondria and nucleus, we found a factor named MIDAS (mitochondrial DNA absence sensitive factor) whose expression was enhanced by the absence of mito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0568902c7e125d27b369f389251fe70
https://doi.org/10.1242/jcs.02645
https://doi.org/10.1242/jcs.02645
Autor:
Shigeo Ohta, Kumi Yamagata, Jennifer Q. Kwong, Yujiro Shidara, Hideaki Oda, Giovanni Manfredi, Kazutoshi Nakano, Takashi Kanamori
Publikováno v:
Cancer Research. 65:1655-1663
The role of mitochondrial dysfunction in cancer has been a subject of great interest and much ongoing investigation. Although most cancer cells harbor somatic mutations in mitochondrial DNA (mtDNA), the question of whether such mutations contribute t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85100369e678e42493be54a2bcac8eb2
https://doi.org/10.1158/0008-5472.can-04-2012
https://doi.org/10.1158/0008-5472.can-04-2012
Autor:
Shinya, Nagai, Sadamitsu, Asoh, Yasuhiro, Kobayashi, Yujiro, Shidara, Takashi, Mori, Misao, Suzuki, Yukichi, Moriyama, Shigeo, Ohta
Publikováno v:
Hepatology research : the official journal of the Japan Society of Hepatology. 37(2)
Apoptosis is involved in hepatic ischemia/reperfusion injury. The protein FNK, constructed from an anti-apoptotic protein Bcl-x(L), exhibits the stronger anticell death activity. We evaluated the effect of FNK on apoptosis after hepatic ischemia and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ba9a89cfcd947dcc622c715cd4eb7a3
https://pubmed.ncbi.nlm.nih.gov/17300709
https://pubmed.ncbi.nlm.nih.gov/17300709
Autor:
Shigeo Ohta, Takashi Mori, Kumi Yamagata, Kiyomi Nishimaki, Sadamitsu Asoh, Yujiro Shidara, S Nagai, Y Miyato
Publikováno v:
Cell death and differentiation. 12(4)
Protection of cells from necrosis would be important for many medical applications. Here, we show protein transduction domain (PTD)-FNK therapeutics based on protein transduction to prevent necrosis and acute hepatic injury with zonal death induced b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b53a19d7b8893ad6e6025e847523723
https://pubmed.ncbi.nlm.nih.gov/15692606
https://pubmed.ncbi.nlm.nih.gov/15692606