Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Yujiro Kidani"'
Autor:
Miya Haruna, Azumi Ueyama, Yoko Yamamoto, Michinari Hirata, Kumiko Goto, Hiroshi Yoshida, Naoko Higuchi, Tetsuya Yoshida, Yujiro Kidani, Yamami Nakamura, Morio Nagira, Atsunari Kawashima, Kota Iwahori, Yasushi Shintani, Naganari Ohkura, Hisashi Wada
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Regulatory T cells (Tregs) suppress the host immune response and maintain immune homeostasis. Tregs also promote cancer progression and are involved in resistance to immune checkpoint inhibitor treatments. Recent studies identified selective
Externí odkaz:
https://doaj.org/article/51a74d2b5acc4db8a5531e85252d6b2f
Autor:
Ryoichi Imamura, Takayuki Kanazawa, Motohide Uemura, Kentaro Nishida, Tetsuya Yoshida, Takeshi Ujike, Atsunari Kawashima, Yoshiyuki Yamamoto, Shimon Sakaguchi, Satoshi Nojima, Akiko Morimoto-Okazawa, Yujiro Kidani, Norio Nonomura, Koji Hatano, Michinari Hirata, Eiichi Morii, Taigo Kato, Hisashi Wada, Naganari Ohkura, Kota Iwahori, Kazutoshi Fujita, Akira Nagahara
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
It is important to evaluate the clinical importance of both CD8 T cells and CD4 T cells expression simultaneously because they have crucial networks in tumour targeting immune responses. In 97 RCC patients, RNA sequencing and gene set enrichment anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07fefbdc2b4ae1323c5ff895d2dcdfad
http://link.springer.com/article/10.1038/s41598-020-63060-1
http://link.springer.com/article/10.1038/s41598-020-63060-1
Autor:
Takayuki Kanazawa, Motohide Uemura, Yujiro Kidani, Makoto Yamasaki, Naganari Ohkura, Michinari Hirata, Taigo Kato, Kota Iwahori, Ryo Kato, Tetsuya Yoshida, Masaaki Sawada, Atsunari Kawashima, Yuichiro Doki, Shimon Sakaguchi, Akiko Morimoto-Okazawa, Takeshi Ujike, Kei Yamamoto, Kazutoshi Fujita, Koji Hatano, Yoko Yamamoto, Norio Nonomura, Hisashi Wada, Kentaro Nishida
Publikováno v:
International Immunology. 32:347-357
Objective CD4+CD8+ T cells are expressed in some cancer patients including those with renal cell carcinoma (RCC). However, no reports have mentioned the clinical importance of this expression. We evaluated the expression of CD4+CD8+ T cells in patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2aea74b0df66751bd36210fbb2261b
https://doi.org/10.1093/intimm/dxaa004
https://doi.org/10.1093/intimm/dxaa004
Autor:
Yujiro Kidani, Wataru Nogami, Yoshiaki Yasumizu, Atsunari Kawashima, Atsushi Tanaka, Yudai Sonoda, Yumi Tona, Kunitaka Nashiki, Reimi Matsumoto, Masaki Hagiwara, Motonao Osaki, Keiji Dohi, Takayuki Kanazawa, Azumi Ueyama, Mai Yoshikawa, Tetsuya Yoshida, Mitsunobu Matsumoto, Kanji Hojo, Satomi Shinonome, Hiroshi Yoshida, Michinari Hirata, Miya Haruna, Yamami Nakamura, Daisuke Motooka, Daisuke Okuzaki, Yasuko Sugiyama, Makoto Kinoshita, Tatsusada Okuno, Taigo Kato, Koji Hatano, Motohide Uemura, Ryoichi Imamura, Kazunori Yokoi, Atsushi Tanemura, Yasushi Shintani, Tadashi Kimura, Norio Nonomura, Hisashi Wada, Masaki Mori, Yuichiro Doki, Naganari Ohkura, Shimon Sakaguchi
Publikováno v:
Proceedings of the National Academy of Sciences. 119
SignificanceImmunosuppressive Foxp3-expressing regulatory T cells (Tregs) in tumor tissues are assumed to be clonally expanding via recognizing tumor-associated antigens. By single-cell RNA sequencing, we have searched for the molecules that are spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4710bc2308f5adf752d06c10e3ca4b
https://doi.org/10.1073/pnas.2114282119
https://doi.org/10.1073/pnas.2114282119
Autor:
Miya Haruna, Azumi Ueyama, Yoko Yamamoto, Michinari Hirata, Kumiko Goto, Hiroshi Yoshida, Naoko Higuchi, Tetsuya Yoshida, Yujiro Kidani, Yamami Nakamura, Morio Nagira, Atsunari Kawashima, Kota Iwahori, Yasushi Shintani, Naganari Ohkura, Hisashi Wada
Publikováno v:
Scientific reports. 12(1)
Regulatory T cells (Tregs) suppress the host immune response and maintain immune homeostasis. Tregs also promote cancer progression and are involved in resistance to immune checkpoint inhibitor treatments. Recent studies identified selective CCR8 exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad897718e284fa4cb0312185d9a6babd
https://pubmed.ncbi.nlm.nih.gov/35354899
https://pubmed.ncbi.nlm.nih.gov/35354899
Autor:
Morihito Okada, Noriko Goda, Shinsuke Sasada, Hideo Shigematsu, Norio Masumoto, Noriyuki Shiroma, Koji Arihiro, Takayuki Kadoya, Yujiro Kidani, Naganari Ohkura, Hiroyoshi Nishikawa, Shimon Sakaguchi
Background Tumor-infiltrating lymphocytes (TILs) in breast cancer comprise immunostimulating and immunosuppressive components. Although FOXP3+ TILs are prototypical immunosuppressive TILs, only effector regulatory T cells (eTreg), a subset of immunos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1625a1def8876497255a4794707f2ec5
https://doi.org/10.21203/rs.2.10900/v1
https://doi.org/10.21203/rs.2.10900/v1
Autor:
Koji Hatano, Makoto Matsushita, Atsunari Kawashima, Eisuke Tomiyama, Kosuke Nakano, Norio Nonomura, Naganari Ohkura, Morio Nagira, Michinari Hirata, Hisashi Wada, Yujiro Kidani, Takayuki Kanazawa, Motohide Uemura, Yoko Koh, Kazutoshi Fujita, Tetsuya Yoshida, Taigo Kato, Yujiro Hayashi, Takeshi Ujike
Publikováno v:
The Journal of Urology. 203:e234
INTRODUCTION AND OBJECTIVE:Regulatory T cells (Treg) play an important role in the construction of immune status within the tumor microenvironment. On the other hand, in order to maximize the thera...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7b8e5ed09ecdb183a636376d40078a1
https://doi.org/10.1097/ju.0000000000000843.02
https://doi.org/10.1097/ju.0000000000000843.02
Autor:
James Badger, Wing, Yohko, Kitagawa, Michela, Locci, Hannah, Hume, Christopher, Tay, Takayoshi, Morita, Yujiro, Kidani, Kyoko, Matsuda, Takeshi, Inoue, Tomohiro, Kurosaki, Shane, Crotty, Cevayir, Coban, Naganari, Ohkura, Shimon, Sakaguchi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(31)
T-follicular regulatory (Tfr) cells, a subset of Foxp3-expressing regulatory T (Treg) cells, have a critical role in the control of antibody responses. Whereas Treg cells express CD25 and are dependent on IL-2, Tfr cells also express the transcriptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e00bdd96b6c481ad24f7131f0c0f9a12
https://pubmed.ncbi.nlm.nih.gov/28698369
https://pubmed.ncbi.nlm.nih.gov/28698369
Autor:
Terumi Kohwi-Shigematsu, Keiko Yasuda, Shimon Sakaguchi, Alexis Vandenbon, Shota Nakamura, Ryoji Kawakami, Yohko Kitagawa, Ichiro Taniuchi, Yujiro Kidani, Keiji Hirota, Naganari Ohkura, Motonari Kondo, Daisuke Motooka
Publikováno v:
Nature immunology. 18(2)
Most Foxp3+ regulatory T (Treg) cells develop in the thymus as a functionally mature T cell subpopulation specialized for immune suppression. Their cell fate appears to be determined before Foxp3 expression; yet molecular events that prime Foxp3- Tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c041f187f06c63f9e099a85d5ea10d3
https://pubmed.ncbi.nlm.nih.gov/29044238
https://pubmed.ncbi.nlm.nih.gov/29044238
Autor:
Atsushi Baba, Ken-ichi Ohshima, Hideyuki Sakai, Takao Kohno, Yujiro Kidani, Mitsuharu Hattori
Publikováno v:
Biochemical and Biophysical Research Communications. 417:1014-1017
Sphingomyelin (SM) plays important roles in regulating structure and function of plasma membrane, but how intracellular localization of SM is regulated in neuronal cells is not understood. Here we show that two isoforms of SM synthase (SMS) are diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f94119c8f6fea919b928f5fc1e18cb03
https://doi.org/10.1016/j.bbrc.2011.12.079
https://doi.org/10.1016/j.bbrc.2011.12.079