Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Yujiro, Nakano"'
Autor:
Yumie Takeshita, Takeo Tanaka, Hiroaki Takayama, Yuki Kita, Hisanori Goto, Yujiro Nakano, Yoshiro Saito, Toshinari Takamura
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 2, Pp 230-235 (2023)
Abstract Aims/Introduction Selenoprotein P (SeP; encoded by SEPP1 in humans) is a hepatokine that causes impaired insulin secretion and insulin resistance. Metformin downregulates SELENOP promoter activity through an adenosine monophosphate‐activat
Externí odkaz:
https://doaj.org/article/f11bd1d0f77a406c927decd1223b8bb0
Autor:
Yumie Takeshita, Yuki Kita, Takeo Tanaka, Hisanori Goto, Yujiro Nakano, Chisato Teramura, Yasufumi Enyama, Toshinari Takamura, the Establishment of Rationale for Antiaging Diabetic Medicine (ERA‐DM) Study Group
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 6, Pp 965-974 (2022)
Abstract Aims/Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) might be less effective in patients with severe hyperglycemia, because hyperglycemia downregulated the GLP‐1 receptor in an animal study. To examine this hypothes
Externí odkaz:
https://doaj.org/article/eaedd379a2fb4663bf3d9039c36984f1
Autor:
Yumie Takeshita, Chisato Teramura, Kyoko Kamoshita, Hiroaki Takayama, Hiromi Nakagawa, Yasufumi Enyama, Kiyo‐Aki Ishii, Takeo Tanaka, Hisanori Goto, Yujiro Nakano, Sachie Osada, Yoshiaki Tanaka, Kumpei Tokuyama, Toshinari Takamura
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 3, Pp 532-542 (2022)
ABSTRACT Aim Selenoprotein P (SeP, encoded by SELENOP in humans) is a hepatokine that causes insulin resistance in the liver and skeletal muscle. It was found that polyunsaturated fatty acid eicosapentaenoic acid (EPA) downregulates Selenop expressio
Externí odkaz:
https://doaj.org/article/2291939474354f1ba9a6bcaefcac3fa8
Publikováno v:
JCEM Case Reports; Aug2024, Vol. 2 Issue 8, p1-4, 4p
Autor:
Chiaki, Nomura, Yujiro, Nakano, Takeo, Tanaka, Kosuke Robert, Shima, Mitsuhiro, Kometani, Takehiro, Kanamori, Hiroko, Ikeda, Yumie, Takeshita, Takashi, Yoneda, Toshinari, Takamura
Publikováno v:
Internal Medicine. 61:3693-3698
Localization of ectopic cyclic Cushing's syndrome, which causes life-threatening complications, is challenging. A 70-year-old woman showed cyclic hypokalemia and hyperglycemia and was diagnosed with cyclic ectopic Cushing's syndrome. Although somatos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a39dc11771130619595c3e10ac88a3e5
https://doi.org/10.2169/internalmedicine.9238-21
https://doi.org/10.2169/internalmedicine.9238-21
Autor:
Yujiro Nakano, Masanori Murakami, Kazunari Hara, Tatsuya Fukuda, Masato Horino, Akira Takeuchi, Yoshihiro Niitsu, Kumiko Shiba, Kazutaka Tsujimoto, Chikara Komiya, Minato Yokoyama, Kenji Ikeda, Takanobu Yoshimoto, Yasuhisa Fujii, Tetsuya Yamada
Publikováno v:
Clinical Endocrinology. 98:323-331
Primary aldosteronism (PA) is a major cause of secondary hypertension and is associated with chronic renal injury. The glomerular filtration rate (GFR) in PA rapidly decreases after the removal of glomerular hyperfiltration due to aldosterone excess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f50447374bc2bafa91fab264021117
https://doi.org/10.1111/cen.14849
https://doi.org/10.1111/cen.14849
Autor:
Yumie Takeshita, Masao Honda, Kenichi Harada, Yuki Kita, Noboru Takata, Hiromasa Tsujiguchi, Takeo Tanaka, Hisanori Goto, Yujiro Nakano, Noriho Iida, Kuniaki Arai, Tatsuya Yamashita, Eishiro Mizukoshi, Hiroyuki Nakamura, Shuichi Kaneko, Toshinari Takamura
Publikováno v:
Diabetes Care. 45:2064-2075
OBJECTIVE Nonalcoholic fatty liver disease (NAFLD) is a liver phenotype of type 2 diabetes and obesity. Currently, the efficacy of sodium–glucose cotransporter 2 (SGLT2) inhibitors and sulfonylureas in liver pathology and hepatic gene expression pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b17d01751e39383eea473ea85a4c74
https://doi.org/10.2337/dc21-2049
https://doi.org/10.2337/dc21-2049
Autor:
Qifang Li, Kiyo-aki Ishii, Kyoko Kamoshita, Kenta Takahashi, Halimulati Abuduwaili, Hiroaki Takayama, Cynthia M Galicia-Medina, Ryota Tanida, Hein Ko Oo, Guzel Gafiyatullina, Xingyu Yao, Tuerdiguli Abuduyimiti, Jun Hamazaki, Hisanori Goto, Yujiro Nakano, Yumie Takeshita, Kenichi Harada, Shigeo Murata, Toshinari Takamura
Publikováno v:
Endocrinology. 164
Muscle atrophy is the cause and consequence of obesity. Proteasome dysfunction mediates obesity-induced endoplasmic reticulum (ER) stress and insulin resistance in the liver and adipose tissues. However, obesity-associated regulation of proteasome fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23ef8a866abf44f78e6ee58f6c80e744
https://doi.org/10.1210/endocr/bqad065
https://doi.org/10.1210/endocr/bqad065
Autor:
Halimulati Abuduwaili, Kyoko Kamoshita, Kiyo-Aki Ishii, Kenta Takahashi, Tuerdiguli Abuduyimiti, Li Qifang, Yuki Isobe, Hisanori Goto, Yujiro Nakano, Yumie Takeshita, Hiroaki Takayama, Kenichi Harada, Toshinari Takamura
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism.
The quality of skeletal muscle is maintained by a balance between protein biosynthesis and degradation. Disruption in this balance results in sarcopenia. However, its underlying mechanisms remain under-investigated. Selenoprotein P (SeP; encoded by S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed20d4229ebd55b63b98041bf3fffdef
https://doi.org/10.1152/ajpendo.00270.2022
https://doi.org/10.1152/ajpendo.00270.2022
Autor:
Yujiro Nakano, Koshi Hashimoto, Noriaki Ohkiba, Hideyuki Okuma, Isao Minami, Hiromitsu Takahashi, Yuji Tanaka, Takanobu Yoshimoto, Tetsuya Yamada
Publikováno v:
Case Reports in Endocrinology, Vol 2019 (2019)
Refractory hypothyroidism is caused by decreased gut absorption, increased metabolism, and poor compliance. Previous studies suggested that the weekly oral, suppository, or intramuscular administration of levothyroxine (LT4) is an effective treatment
Externí odkaz:
https://doaj.org/article/99fdd114328d4c82b33c6b5c79f6e18f