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Methotrexate-associated lymphoproliferative disorders with angioimmunoblastic T-cell lymphoma-like features accompanied by gamma-heavy chain disease in a patient with rheumatoid arthritis

Autor: Motoaki Shiratsuchi, Hiroki Muta, Mariko Tsuda, Junichi Kiyasu, Yoshihiro Ogawa, Kouichi Ohshima, Fumiko Arakawa, Yuji Yufu, Shojiro Haji, Motohiko Ikeda, Takamitsu Matsushima, Hiroaki Miyoshi, Yoshimichi Tachikawa, Yasuhiro Tsukamoto

Publikováno v: Pathology International. 68:485-490

Although gamma heavy chain disease (γ-HCD) lesions occasionally morphologically resemble angioimmunoblastic T-cell lymphoma (AITL), no association has been described in detail due to the rarity of the disease. In this report, we present a rare manif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5117885a6cb2bce82f2b20241dfff91f
https://doi.org/10.1111/pin.12703

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Fatal Disseminated Tuberculosis during Treatment with Ruxolitinib Plus Prednisolone in a Patient with Primary Myelofibrosis: A Case Report and Review of the Literature

Autor: Mariko Tsuda, Yoshihiro Ogawa, Motoaki Shiratsuchi, Yuji Yufu, Yasuhiro Tsukamoto, Motohiko Ikeda, Junichi Kiyasu

Publikováno v: Internal Medicine

A 73-year-old man with primary myelofibrosis (PMF) was being treated with hydroxyurea, which was changed to ruxolitinib treatment because of worsening constitutional symptoms. Although ruxolitinib rapidly induced relief, he developed a high-grade fev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d515f832f679d6e050d6dd356544d88
http://europepmc.org/articles/PMC5980814

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Spontaneous splenic rupture in a patient with light-chain deposition disease undergoing autologous peripheral blood stem cell transplantation

Autor: Shojiro, Haji, Junichi, Kiyasu, Yoshimichi, Tachikawa, Jiro, Toyonaga, Motohiko, Ikeda, Mariko, Tsuda, Yasuhiro, Tsukamoto, Mitsuo, Kozuru, Yuji, Yufu

Publikováno v: [Rinsho ketsueki] The Japanese journal of clinical hematology. 57(6)

Light-chain deposition disease (LCDD) is a rare plasma cell neoplasm that secretes an abnormal immunoglobulin light chain, which is deposited in tissues, leading to organ dysfunction. Spontaneous splenic rupture is a rare and life-threatening complic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::94c6936112f037c35320a8f436892d51
https://pubmed.ncbi.nlm.nih.gov/27384856

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Expression of programmed cell death ligand 1 is associated with poor overall survival in patients with diffuse large B-cell lymphoma

Autor: Motoaki Shiratsuchi, Koichi Ohshima, Koichi Akashi, Fumiko Arakawa, Daisuke Niino, Akie Hirata, Ayako Ichikawa, Ryoichi Takayanagi, Takashi Okamura, Yasunobu Abe, Ilseung Choi, Koji Nagafuji, Yasuo Sugita, Yuji Yufu, Junichi Kiyasu, Hiroaki Miyoshi, Naokuni Uike

Publikováno v: Blood. 126(19)

Programmed cell death ligand 1 (PD-L1) is expressed on both select diffuse large B-cell lymphoma (DLBCL) tumor cells and on tumor-infiltrating nonmalignant cells. The programmed cell death 1 (PD-1)/PD-L1 pathway inhibits host antitumor responses; how

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a2921acc03b2265f942a74fc391e5b
https://pubmed.ncbi.nlm.nih.gov/26542250

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Primary Macroglobulinemia with t(11;18)(q21;q21)

Autor: Yuji Yufu, Junji Nishimura, Koichiro Muta, Satoshi Shiokawa, Nobuhisa Hirase, Hajime Nawata, Yasunobu Abe

Publikováno v: Cancer Genetics and Cytogenetics. 117:113-117

These are the first cases of primary macroglobulinemia (PMG) with t(11;18)(q21;q21) reported in the literature. The first case was a 77-year-old man with macroglobulinemia (serum IgM: 8.36 g/dL). Abnormal lymphoid cells were detected in the blood and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b5e31e50d32fc5d39e57e94c3a8471
https://doi.org/10.1016/s0165-4608(99)00156-9

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A new multiple myeloma cell line, MEF-1, possesses cyclin d1 overexpression and the p53 mutation

Autor: Ilseung Choi, Toshiyasu Taniguchi, Naokuni Uike, Toru Motokura, Koichi Ohshima, Shigeo Nakamura, Tatsuro Goto, Yasushi Yatabe, Mitsuo Kozuru, Yuji Yufu

Publikováno v: ResearcherID

BACKGROUND The t(11;14)(q13;q32) translocation with cyclin D1 overexpression commonly is found in multiple myeloma (MM) and in mantle cell lymphoma (MCL). Several reports have shown that p53 mutations in MCL lead to blastoid transformation and a wors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5978b75d8ed4efe40a4e9ed1d7e64ffe
https://doi.org/10.1002/(sici)1097-0142(19990415)85:8<1750::aid-cncr15>3.0.co

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Allogeneic stem-cell transplantation with reduced conditioning intensity as a novel immunotherapy and antiviral therapy for adult T-cell leukemia/lymphoma

Autor: Mari Kannagi, Hiroyoshi Hattori, Ryuji Tanosaki, Yoshio Saburi, Mine Harada, Naokuni Uike, Jun Okamura, Masato Masuda, Atae Utsunomiya, Masao Tomonaga, Nobuhiro Kimura, Fumio Kawano, Yuji Yufu, Hiroshi Kikuchi, Shunro Sonoda

Publikováno v: Blood. 105:4143-4145

Sixteen patients with adult T-cell leukemia/lymphoma (ATL) who were all over 50 years of age underwent allogeneic stem cell transplantation with reduced-conditioning intensity (RIST) from HLA-matched sibling donors after a conditioning regimen consis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a211fa03f1c622456f61b04fedf92454
https://doi.org/10.1182/blood-2004-11-4193

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