Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yuji Takeyama"'
Autor:
Shoma Yamamoto, Minoru Kato, Yuji Takeyama, Yukari Azuma, Nao Yukimatsu, Yukiyoshi Hirayama, Taiyo Otoshi, Takeshi Yamasaki, Masaki Fujioka, Min Gi, Hideki Wanibuchi, Junji Uchida
Publikováno v:
British Journal of Cancer.
Background Radiotherapy (RT) has recently been highlighted as a partner of immune checkpoint inhibitors. The advantages of RT include activation of lymphocytes while it potentially recruits immunosuppressive cells, such as myeloid-derived suppressor
Autor:
Minoru Kato, Taro Iguchi, Satoshi Tamada, Yuji Takeyama, Yukari Azuma, Yasuomi Shimizu, Tatsuya Nakatani, Hideki Wanibuchi, Min Gi, Takeshi Yamasaki
Publikováno v:
Cancer Letters. 479:89-99
Myeloid-derived suppressor cells (MDSCs) are one of the key players that contribute to immune evasion. The purpose of the present study was to investigate whether MDSCs could be a novel target for the treatment of cisplatin-resistant bladder cancer.
Autor:
Minoru Kato, Katsuyuki Kuratsukuri, Shoma Yamamoto, Yukiyoshi Hirayama, Junji Uchida, Takeshi Yamasaki, Yuji Takeyama, Nao Yukimatsu, Taiyo Otoshi
Publikováno v:
Urologic oncology. 40(5)
Background Recently, switch maintenance with avelumab has been approved for the treatment of advanced or metastatic urothelial carcinoma (UC), with no progression after four to six cycles of first-line platinum-based chemotherapy. However, the optima
Autor:
Anna Kakehashi, Minoru Kato, Satoshi Tamada, Yuji Takeyama, Tatsuya Nakatani, Min Gi, Masaki Fujioka, Yasuomi Shimizu, Hideki Wanibuchi
Publikováno v:
Experimental and Therapeutic Medicine
Androgen signal has been recently suggested to be associated with the progression of bladder cancer. Steroid sulfatase (STS) is a steroid sulfate activation enzyme, considered to be one of the key enzymes in the androgen signaling pathway. However, t
Autor:
Takeshi Yamasaki, Satoshi Tamada, Tatsuya Nakatani, Katsuyuki Kuratsukuri, Minoru Kato, Yuji Takeyama, Taro Iguchi, Chikako Nishihara
Publikováno v:
International Journal of Clinical Oncology. 23:944-950
The aim of this study was to evaluate the efficacy and toxicities of second-line chemotherapy regimens with docetaxel and gemcitabine (GD), or paclitaxel and gemcitabine (GP) for advanced or metastatic urothelial carcinoma (UC) that did not respond t
Autor:
Yuji Takeyama, Minoru Kato, Sayaka Yasuda, Taro Iguchi, Tatsuya Nakatani, Yasuomi Shimizu, Satoshi Tamada, Takeshi Yamasaki
Publikováno v:
Journal of Urology. 197
Autor:
Minoru Kato, Tatsuya Nakatani, Yasuomi Shimizu, Taro Iguchi, Satoshi Tamada, Yuji Takeyama, Kosuke Hamada
Publikováno v:
Journal of Clinical Oncology. 37:415-415
415 Background: The emergence of immune checkpoint inhibitors (ICI) has brought hope for cure and survival for those suffering from various cancers, including bladder cancer. However, the response rate of ICI monotherapy is modest, and recent reports
Autor:
Sayaka Yasuda, Satoshi Tamada, Taro Iguchi, Takeshi Yamasaki, Yuji Takeyama, Tatsuya Nakatani, Minoru Kato, Yasuomi Shimizu, Kosuke Hamada
Publikováno v:
Journal of Clinical Oncology. 37:293-293
293 Background: In Asia, including Japan, combined androgen blockade (CAB) therapy with bicalutamide is widely used for metastatic prostate cancer. Alternative anti-androgen therapy (AAT) with flutamide (FLU) after CAB therapy with bicalutamide was c
Autor:
Yasuomi Shimizu, Satoshi Tamada, Kosuke Hamada, Taro Iguchi, Tatsuya Nakatani, Minoru Kato, Yuji Takeyama
Publikováno v:
Journal of Clinical Oncology. 37:302-302
302 Background: Expression of androgen receptor (AR) splice variant 7 (AR-V7) has been identified as a mechanism associated with the development of castration-resistant prostate cancer (CRPC), but a potential link between AR-V7 expression and resista