Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yuji Sumita"'
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 19:175-187
The synthesis of cyclic ADP-carbocyclic-ribose (2), as a stable mimic for cyclic ADP-ribose, was investigated. Construction of the 18-membered backbone structure was successfully achieved by condensation of the two phosphate groups of 19, possibly du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216c60b9b12751330d967d1947a14042
https://doi.org/10.1080/15257770008033002
https://doi.org/10.1080/15257770008033002
Publikováno v:
Nucleosides and Nucleotides. 18:1035-1053
The interplay of enthalpy of the gauche effect (ΔH°GE) of the [X3′-C3′-C4′-O4′] fragment in various 3′-substituted (X) 2′,3′-dideoxythymidine derivatives 1–7 and the inherent anomeric effect drives the two-state North ⇄ South equi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a951a8b7019f5f088f6146fb05caead
https://doi.org/10.1080/15257779908041642
https://doi.org/10.1080/15257779908041642
Publikováno v:
Nucleic Acids Research. 26(22):5067-5072
The synthesis and properties of oligodeoxynucleotides (ODNs) containing 2'- O -(trifluoromethyl)adenosine (2) are described. 2'- O -(Trifluoromethyl)adenosine (2) or N 6-(benzoyl)-2'- O -(trifluoromethyl)adenosine (6) was obtained in 22 or 32% yield
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca83b973b8e12554e3ba96467ea7265
http://hdl.handle.net/2115/46964
http://hdl.handle.net/2115/46964
Publikováno v:
Tetrahedron Letters. 39:7341-7344
Formation of symmetric 36-membered-ring product 14 was observed in the synthetic study of a stable mimic of cyclic ADP-ribose (cADPR, 1). When 8-bromo-N1-[5-(phenylthiophosphoryl)carbocyclic-ribosyl]inosine 5′-phosphate derivative 5 was treated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28aa7eb98776662da77e8fb32f48e070
https://doi.org/10.1016/s0040-4039(98)01575-5
https://doi.org/10.1016/s0040-4039(98)01575-5
Publikováno v:
The Journal of Organic Chemistry. 63:1986-1994
Cyclic ADP-ribose (cADPR, 1) is a general mediator involved in cellular Ca2+ signaling. However, both the biological and chemical instability of cADPR limit studies on its physiological role. We designed cyclic ADP-carbocyclic-ribose (3) and its inos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3357331ed17def8a1d18f3f798e194b0
https://doi.org/10.1021/jo9717797
https://doi.org/10.1021/jo9717797
Publikováno v:
ChemInform. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb9249d15a6a764e8c39996cfa6319b5
https://doi.org/10.1002/chin.200029190
https://doi.org/10.1002/chin.200029190
Autor:
Noriko Yamamoto, Kiyonoshin Ichikawa, Kazuyuki Furuya, Keigo Hanada, Motonori Miyakawa, Seiji Amano, Hiroaki Nejishima, Nao Oguro, Yuji Sumita, Tsutomu Nakamura
Publikováno v:
Biologicalpharmaceutical bulletin. 26(11)
A novel nonsteroidal androgen receptor (AR) binder, S-40503, was successfully generated in order to develop selective androgen receptor modulators (SARMs). We evaluated the binding specificity for nuclear receptors (NRs) and osteoanabolic activities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e00cf32fb7c62dde380ee7adc71bfdf
https://pubmed.ncbi.nlm.nih.gov/14600402
https://pubmed.ncbi.nlm.nih.gov/14600402