Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Yuji Sugiu"'
Autor:
Tsutomu Imaizumi, Hisashi Kai, Hirohisa Kato, Fumitaka Kuwahara, Yuji Sugiu, Yukihiko Seki, Akinori Kimura, Hirohumi Nishi, Akihiko Muraishi
Publikováno v:
Circulation Research. 83:594-601
Abstract —Several mutations of cardiac β-myosin heavy chain (β-MHC) gene were reported in patients with hypertrophic cardiomyopathy (HCM). Involvement of proto-oncogenes has been shown in the mechanism of experimental cardiac hypertrophy. This st
Autor:
Yuji Sugiu, Hironori Toshima, Kyo Adachi, Toshihiko Sakanashi, Fujiura Y, Akira Nozuhara, Mayumi F, T. Hidaka
Publikováno v:
Biochemical and Biophysical Research Communications. 195:945-951
A deletion of about 4 kb has been determined in the mutated mitochondrial DNA (mtDNA) in cardiomyocytes with chronic doxorubicin (DOX)-induced cardiotoxicity in mouse. The incidence of the mtDNA deletion increased with the dosage and with the duratio
Publikováno v:
The Kurume medical journal. 40(2)
To clarify the abnormalities of myocardial membrane structure in cardiomyopathy, the density of intramembranous particles (IMP) of mitochondria, sarcoplasmic reticulum and sarcolemma, and the number of caveolar necks was evaluated by freeze-fracture