Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Yuji Suehiro"'
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Cancer is one of the main causes of human death. Here, we focus on the B-cell lymphoma 7 protein family member B (BCL7B) gene, an accessory subunit of the SWI/SNF chromatin-remodelling complex. To characterize the function of BCL7B, heterozy
Externí odkaz:
https://doaj.org/article/5fdba5df908a4a818136fbc3c9f40645
Publikováno v:
iScience, Vol 26, Iss 10, Pp 108067- (2023)
Summary: Dietary supplied double-stranded RNA (dsRNA) can trigger RNA interference (RNAi) systemically in some animals, including the nematode Caenorhabditis elegans. Although this phenomenon has been utilized as a major tool for gene silencing in C.
Externí odkaz:
https://doaj.org/article/25df013d2cef4b9bb3ae00dd4cff2757
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106930- (2023)
Summary: Double-stranded RNA (dsRNA) regulates gene expression in a sequence-dependent manner. In Caenorhabditis elegans, dsRNA spreads through the body and leads to systemic RNA silencing. Although several genes involved in systemic RNAi have been g
Externí odkaz:
https://doaj.org/article/4274b158f7e842b7a90539c33c275575
Autor:
Yuji Suehiro, Sawako Yoshina, Tomoko Motohashi, Satoru Iwata, Katsufumi Dejima, Shohei Mitani
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract With the development of massive parallel sequencing technology, it has become easier to establish new model organisms that are ideally suited to the specific biological phenomena of interest. Considering the history of research using classic
Externí odkaz:
https://doaj.org/article/301ba8ccca06423d805b46c450f7433e
Autor:
Katsufumi Dejima, Sayaka Hori, Satoru Iwata, Yuji Suehiro, Sawako Yoshina, Tomoko Motohashi, Shohei Mitani
Publikováno v:
Cell Reports, Vol 22, Iss 1, Pp 232-241 (2018)
Summary: Balancer chromosomes are critical tools for genetic research. In C. elegans, reciprocal translocations that lead to aneuploidy have been widely used to maintain lethal and sterile mutations in stable stocks. Here, we generated a set of aneup
Externí odkaz:
https://doaj.org/article/9bef06a53643476caa2e1e182ecb4fe0
Publikováno v:
Biochemistry and Biophysics Reports, Vol 5, Iss C, Pp 70-76 (2016)
We established a method to generate integration from extrachromosomal arrays with the CRISPR/Cas9 system. Multi-copy transgenes were integrated into the defined loci of chromosomes by this method, while a multi-copy transgene is integrated into rando
Externí odkaz:
https://doaj.org/article/6c657a027f8d4cc9b0eab2992ffd75b0
Publikováno v:
PLoS Genetics, Vol 14, Iss 6, p e1007477 (2018)
Optimization of the types and timing of avoidance behaviors depending on the intensity of a noxious stimulus is essential for survival; however, processing in the central nervous system and its developmental basis are largely unknown. Here, we report
Externí odkaz:
https://doaj.org/article/3d9157c212f44def8ff3b8c497dadfbe
Autor:
Satomi Tsuboko, Tetsuaki Kimura, Minori Shinya, Yuji Suehiro, Teruhiro Okuyama, Atsuko Shimada, Hiroyuki Takeda, Kiyoshi Naruse, Takeo Kubo, Hideaki Takeuchi
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112527 (2014)
Genetic polymorphisms are thought to generate intraspecific behavioral diversities, both within and among populations. The mechanisms underlying genetic control of behavioral properties, however, remain unclear in wild-type vertebrates, including hum
Externí odkaz:
https://doaj.org/article/ba2405425c184617b7338e9f1cf578da
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114680 (2014)
Conditional knockout (cKO) based on site-specific recombination (SSR) technology is a powerful approach for estimating gene functions in a spatially and temporally specific manner in many model animals. In Caenorhabditis elegans (C. elegans), spatial
Externí odkaz:
https://doaj.org/article/c89c3cf9e9eb48d6a696d09c03dee595
Autor:
Teruhiro Okuyama, Yasuko Isoe, Masahito Hoki, Yuji Suehiro, Genki Yamagishi, Kiyoshi Naruse, Masato Kinoshita, Yasuhiro Kamei, Atushi Shimizu, Takeo Kubo, Hideaki Takeuchi
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66597 (2013)
BACKGROUND: Genetic mosaic techniques have been used to visualize and/or genetically modify a neuronal subpopulation within complex neural circuits in various animals. Neural populations available for mosaic analysis, however, are limited in the vert
Externí odkaz:
https://doaj.org/article/d92baf12d8bd430d868b1acd82677caa