Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Yuji Shiozaki"'
Autor:
Minori Uga, Ichiro Kaneko, Yuji Shiozaki, Megumi Koike, Naoko Tsugawa, Peter W. Jurutka, Ken-Ichi Miyamoto, Hiroko Segawa
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 717 (2024)
Vitamin D hydroxylation in the liver/kidney results in conversion to its physiologically active form of 1,25-dihydroxyvitamin D3 [1,25(OH)2D3]. 1,25(OH)2D3 controls gene expression through the nuclear vitamin D receptor (VDR) mainly expressed in inte
Externí odkaz:
https://doaj.org/article/04137747bd4e4e95b3446a9ee26d3215
Publikováno v:
Endocrines, Vol 4, Iss 3, Pp 607-615 (2023)
Phosphorus is essential for all living organisms. It plays an important role in maintaining biological functions, such as energy metabolism, cell membrane formation, and bone mineralization. Various factors in the intestine, kidneys, and bones regula
Externí odkaz:
https://doaj.org/article/267b57815bb14160ad2836a8a1738491
Autor:
Sumire Sasaki, Yuji Shiozaki, Ai Hanazaki, Megumi Koike, Kazuya Tanifuji, Minori Uga, Kota Kawahara, Ichiro Kaneko, Yasuharu Kawamoto, Pattama Wiriyasermkul, Tomoka Hasegawa, Norio Amizuka, Ken-ichi Miyamoto, Shushi Nagamori, Yoshikatsu Kanai, Hiroko Segawa
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Renal type II sodium-dependent inorganic phosphate (Pi) transporters NaPi2a and NaPi2c cooperate with other organs to strictly regulate the plasma Pi concentration. A high Pi load induces expression and secretion of the phosphaturic hormones
Externí odkaz:
https://doaj.org/article/8f8554629dc4405c8c8179c1a857f3c7
Autor:
Yuji Shiozaki, Shinobu Miyazaki–Anzai, Kayo Okamura, Audrey L. Keenan, Masashi Masuda, Makoto Miyazaki
Publikováno v:
iScience, Vol 23, Iss 5, Pp - (2020)
Summary: Excessive levels of saturated fatty acids are toxic to vascular smooth muscle cells (VSMCs). We previously reported that mice lacking VSMC-stearoyl-CoA desaturase (SCD), a major enzyme catalyzing the detoxification of saturated fatty acids,
Externí odkaz:
https://doaj.org/article/dc28b81c37ce4cc2a233163c97fe4ad3
Autor:
Ai Hanazaki, Kayo Ikuta, Shohei Sasaki, Sumire Sasaki, Megumi Koike, Kazuya Tanifuji, Yuki Arima, Ichiro Kaneko, Yuji Shiozaki, Sawako Tatsumi, Tomoka Hasegawa, Norio Amizuka, Ken‐ichi Miyamoto, Hiroko Segawa
Publikováno v:
Physiological Reports, Vol 8, Iss 3, Pp n/a-n/a (2020)
Abstract SLC34A3/NPT2c/NaPi‐2c/Npt2c is a growth‐related NaPi cotransporter that mediates the uptake of renal sodium‐dependent phosphate (Pi). Mutation of human NPT2c causes hereditary hypophosphatemic rickets with hypercalciuria. Mice with Npt
Externí odkaz:
https://doaj.org/article/5c073f670fde43a4b70470221bc3277b
Autor:
Shinobu Miyazaki-Anzai, Masashi Masuda, Shohei Kohno, Moshe Levi, Yuji Shiozaki, Audrey L. Keenan, Makoto Miyazaki
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 9, Pp 1709-1713 (2018)
Simultaneous activation of bile acid receptors farnesoid X receptor (FXR) and G protein-coupled bile acid receptor 1 (TGR5) by INT-767 significantly reduces atherosclerotic formation. In this study, we investigated the effect of simultaneous inactiva
Externí odkaz:
https://doaj.org/article/78a4964df26e4607a6355d39d21feecd
Autor:
Shohei Sasaki, Hiroko Segawa, Ai Hanazaki, Ruri Kirino, Toru Fujii, Kayo Ikuta, Miwa Noguchi, Sumire Sasaki, Megumi Koike, Kazuya Tanifuji, Yuji Shiozaki, Ichiro Kaneko, Sawako Tatsumi, Takaaki Shimohata, Yoshichika Kawai, Sonoko Narisawa, José Luis Millán, Ken-ichi Miyamoto
Publikováno v:
Kidney & Blood Pressure Research, Vol 43, Iss 5, Pp 1409-1424 (2018)
Background/Aims: Hyperphosphatemia is a serious complication of late-stage chronic kidney disease (CKD). Intestinal inorganic phosphate (Pi) handling plays an important role in Pi homeostasis in CKD. We investigated whether intestinal alkaline phosph
Externí odkaz:
https://doaj.org/article/36c57e898e644c9e9d8a52246f8a75e4
Autor:
Kazuya Tanifuji, Yuji Shiozaki, Megumi Koike, Minori Uga, Aoi Komiya, Mizuki Miura, Ayami Higashi, Takaaki Shimohata, Akira Takahashi, Noriko Ishizuka, Hisayoshi Hayashi, Yasuhiro Ichida, Shuichi Ohtomo, Naoshi Horiba, Ken-ichi Miyamoto, Hiroko Segawa
Publikováno v:
The Journal of Medical Investigation. 70:260-270
Autor:
Sumire Sasaki, Megumi Koike, Kazuya Tanifuji, Minori Uga, Kota Kawahara, Aoi Komiya, Mizuki Miura, Yamato Harada, Yuki Hamaguchi, Shohei Sasaki, Yuji Shiozaki, Ichiro Kaneko, Ken-ichi Miyamoto, Hiroko Segawa
Publikováno v:
The journal of medical investigation : JMI. 69(3.4)
Phosphate (Pi)-containing food additives are used in several forms. Polyphosphate (PPi) salt has more harmful effects than monophosphate (MPi) salt on bone physiology and renal function. This study aimed to analyze the levels of parathyroid hormone P
Autor:
Shizuya, Shintomi, Masako, Arakida, Azumi, Hamasaki, Satoshi, Saito, Yuki, Ichihara, Satoru, Domoto, Shintaro, Sawa, Ryo, Ikeda, Yuji, Shiozaki, Kazuko, Shiraishi, Hiroshi, Niinami
Publikováno v:
Kyobu geka. The Japanese journal of thoracic surgery. 75(11)
Nurse practitioner (NP) is widely known to be an essential position of medical team in the United States, but has not yet been established as an official qualification in Japan. NP in Japan (NP-J) is accepted instead of NP, but they are not the same.