Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Yuji Shimoda"'
Autor:
Takeshi Nagashima, Ken Yamaguchi, Kenichi Urakami, Yuji Shimoda, Sumiko Ohnami, Keiichi Ohshima, Tomoe Tanabe, Akane Naruoka, Fukumi Kamada, Masakuni Serizawa, Keiichi Hatakeyama, Shumpei Ohnami, Koji Maruyama, Tohru Mochizuki, Maki Mizuguchi, Akio Shiomi, Yasuhisa Ohde, Etsuro Bando, Teiichi Sugiura, Takashi Mukaigawa, Seiichiro Nishimura, Yasuyuki Hirashima, Koichi Mitsuya, Shusuke Yoshikawa, Yoshio Kiyohara, Yasuhiro Tsubosa, Hirohisa Katagiri, Masashi Niwakawa, Kaoru Takahashi, Hiroya Kashiwagi, Yoshichika Yasunaga, Yuji Ishida, Takashi Sugino, Hirotsugu Kenmotsu, Masanori Terashima, Mitsuru Takahashi, Katsuhiko Uesaka, Yasuto Akiyama
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract In cancer genome analysis, identifying pathogenic alterations and assessing their effects on oncogenic processes is important. Although whole exome sequencing (WES) can effectively detect such changes, driver alterations could not be identif
Externí odkaz:
https://doaj.org/article/78e02debd67d4858aa07bf66640f5372
Autor:
Keiichi Hatakeyama, Koji Muramatsu, Takeshi Nagashima, Hiroyuki Ichida, Yuichi Kawanishi, Ryutaro Fukumura, Keiichi Ohshima, Yuji Shimoda, Sumiko Ohnami, Shumpei Ohnami, Koji Maruyama, Akane Naruoka, Hirotsugu Kenmotsu, Kenichi Urakami, Yasuto Akiyama, Takashi Sugino, Ken Yamaguchi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract The detection of copy number variations (CNVs) and somatic mutations in cancer is important for the selection of specific drugs for patients with cancer. In cancers with sporadic tumor cells, low tumor content prevents the accurate detection
Externí odkaz:
https://doaj.org/article/3803f9f730f74fb287285c07c11200a5
Autor:
Sumiko Ohnami, Akane Naruoka, Mitsuhiro Isaka, Maki Mizuguchi, Sou Nakatani, Fukumi Kamada, Yuji Shimoda, Ai Sakai, Keiichi Ohshima, Keiichi Hatakeyama, Kouji Maruyama, Yasuhisa Ohde, Hirotsugu Kenmotsu, Toshiaki Takahashi, Yasuto Akiyama, Takeshi Nagashima, Kenichi Urakami, Shumpei Ohnami, Ken Yamaguchi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The differences in genetic susceptibility to lung adenocarcinoma and squamous cell carcinoma remain unclear. We developed a customized, targeted gene sequencing panel for efficient and sensitive identification of germline variants, including
Externí odkaz:
https://doaj.org/article/2f07bf26841c4645bc84e2251e27d091
Autor:
Keiichi Hatakeyama, Koji Muramatsu, Takeshi Nagashima, Yuichi Kawanishi, Ryutaro Fukumura, Keiichi Ohshima, Yuji Shimoda, Hirotsugu Kenmotsu, Tohru Mochizuki, Kenichi Urakami, Yasuto Akiyama, Takashi Sugino, Ken Yamaguchi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Targeted sequencing offers an opportunity to select specific drugs for cancer patients based on alterations in their genome. However, accurate sequencing cannot be performed in cancers harboring diffuse tumor cells because of low tumor conte
Externí odkaz:
https://doaj.org/article/6695e80cba474b6392ca70861efa1b00
Autor:
Keiichi Hatakeyama, Takeshi Nagashima, Akifumi Notsu, Keiichi Ohshima, Sumiko Ohnami, Shumpei Ohnami, Yuji Shimoda, Akane Naruoka, Koji Maruyama, Akira Iizuka, Tadashi Ashizawa, Hirotsugu Kenmotsu, Tohru Mochizuki, Kenichi Urakami, Yasuto Akiyama, Ken Yamaguchi
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Background Mutation analysis using next-generation sequencing highlights the features of tumors with somatic alterations. However, the mutation profile of double cancer remains unclear. Here, we analyzed tumors derived from the same patient
Externí odkaz:
https://doaj.org/article/c6e030458494413aafb8ee252b5ac89a
Autor:
Keiichi Ohshima, Keiichi Hatakeyama, Takeshi Nagashima, Yuko Watanabe, Kaori Kanto, Yuki Doi, Tomomi Ide, Yuji Shimoda, Tomoe Tanabe, Sumiko Ohnami, Shumpei Ohnami, Masakuni Serizawa, Koji Maruyama, Yasuto Akiyama, Kenichi Urakami, Masatoshi Kusuhara, Tohru Mochizuki, Ken Yamaguchi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Identification of driver genes contributes to the understanding of cancer etiology and is imperative for the development of individualized therapies. Gene amplification is a major event in oncogenesis. Driver genes with tumor-specific amplif
Externí odkaz:
https://doaj.org/article/e4035a2588bc4f009de6291a94d531c3
Autor:
Keiichi Ohshima, Takeshi Nagashima, Keiichi Fujiya, Keiichi Hatakeyama, Yuko Watanabe, Kimiko Morimoto, Fukumi Kamada, Yuji Shimoda, Sumiko Ohnami, Akane Naruoka, Masakuni Serizawa, Shumpei Ohnami, Hirotsugu Kenmotsu, Akio Shiomi, Yasuhiro Tsubosa, Etsuro Bando, Teiichi Sugiura, Takashi Sugino, Masanori Terashima, Katsuhiko Uesaka, Kenichi Urakami, Yasuto Akiyama, Ken Yamaguchi
Publikováno v:
Cancer Research Communications. 3:684-696
Gastrointestinal stromal tumors (GIST) with KIT exon 11 deletions involving in codons 557–558 (KIT Δ557–558) exhibit higher proliferation rates and shorter disease-free survival times compared with GISTs with other KIT exon 11 mutations. We anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceff287e4b8e5be7363e62ad617dbffb
https://doi.org/10.1158/2767-9764.crc-22-0364
https://doi.org/10.1158/2767-9764.crc-22-0364
Autor:
CHIKAKO HOZUMI, AKIRA IIZUKA, TOMOATSU IKEYA, HARUO MIYATA, CHIE MAEDA, TADASHI ASHIZAWA, TAKESHI NAGASHIMA, KENICHI URAKAMI, YUJI SHIMODA, KEIICHI OHSHIMA, KOJI MURAMATSU, TAKASHI SUGINO, AKIO SHIOMI, YASUHISA OHDE, ETSURO BANDO, KENICHIRO FURUKAWA, TEIICHI SUGIURA, TAKASHI MUKAIGAWA, SEIICHIRO NISHIMURA, YASUYUKI HIRASHIMA
Publikováno v:
Cancer Genomics & Proteomics (1109-6535); Jan/Feb2024, Vol. 21 Issue 1, p88-101, 14p
Autor:
Yuji, Shimoda, Takeshi, Nagashima, Kenichi, Urakami, Fukumi, Kamada, Sou, Nakatani, Maki, Mizuguchi, Masakuni, Serizawa, Keiichi, Hatakeyama, Keiichi, Ohshima, Tohru, Mochizuki, Sumiko, Ohnami, Shumpei, Ohnami, Takeshi, Kawakami, Kentaro, Yamazaki, Haruyasu, Murakami, Hirotsugu, Kenmotsu, Akio, Shiomi, Yasuto, Akiyama, Ken, Yamaguchi
Publikováno v:
Biomedical Research. 43:115-126
Next-generation sequencing (NGS) is an integral part of precision medicine, and its power for detecting comprehensive genetic alterations may contribute to treatment decisions for patients with advanced, recurrent, or metastatic cancer. An NGS oncolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dfdaf12e0e6226e1e83cc003fee3e21
https://doi.org/10.2220/biomedres.43.115
https://doi.org/10.2220/biomedres.43.115
Autor:
Ken Yamaguchi, Yasuto Akiyama, Kenichi Urakami, Katsuhiko Uesaka, Masanori Terashima, Takashi Sugino, Teiichi Sugiura, Etsuro Bando, Yasuhiro Tsubosa, Akio Shiomi, Hirotsugu Kenmotsu, Shumpei Ohnami, Masakuni Serizawa, Akane Naruoka, Sumiko Ohnami, Yuji Shimoda, Fukumi Kamada, Kimiko Morimoto, Yuko Watanabe, Keiichi Hatakeyama, Keiichi Fujiya, Takeshi Nagashima, Keiichi Ohshima
Genes for expression signatures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1c897aeb21c42a5d1b2b9b52dc0d2a
https://doi.org/10.1158/2767-9764.22684195
https://doi.org/10.1158/2767-9764.22684195
