Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Yuji Shiba"'
Autor:
Yuki Tanaka, Shin Kadota, Jian Zhao, Hideki Kobayashi, Satomi Okano, Masaki Izumi, Yusuke Honda, Hajime Ichimura, Naoko Shiba, Takeshi Uemura, Yuko Wada, Shinichiro Chuma, Tsutomu Nakada, Shugo Tohyama, Keiichi Fukuda, Mitsuhiko Yamada, Tatsuichiro Seto, Koichiro Kuwahara, Yuji Shiba
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Background Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) can be used to treat heart diseases; however, the optimal maturity of hiPSC-CMs for effective regenerative medicine remains unclear. We aimed to investigate th
Externí odkaz:
https://doaj.org/article/b753b6a2aa8c41179aa9cf4247289cee
Autor:
Naoko Shiba, Xiao Yang, Mitsuto Sato, Shin Kadota, Yota Suzuki, Masahiro Agata, Kohei Nagamine, Masaki Izumi, Yusuke Honda, Tomoya Koganehira, Hideki Kobayashi, Hajime Ichimura, Shinichiro Chuma, Junichi Nakai, Shugo Tohyama, Keiichi Fukuda, Daigo Miyazaki, Akinori Nakamura, Yuji Shiba
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102060- (2023)
Exon-skipping therapy is a promising treatment strategy for Duchenne muscular dystrophy (DMD), which is caused by loss-of-function mutations in the DMD gene encoding dystrophin, leading to progressive cardiomyopathy. In-frame deletion of exons 3–9
Externí odkaz:
https://doaj.org/article/feccee7ab1c242b9ad7ff132d76464c6
Autor:
Junjun Li, Itsunari Minami, Motoko Shiozaki, Leqian Yu, Shin Yajima, Shigeru Miyagawa, Yuji Shiba, Nobuhiro Morone, Satsuki Fukushima, Momoko Yoshioka, Sisi Li, Jing Qiao, Xin Li, Lin Wang, Hidetoshi Kotera, Norio Nakatsuji, Yoshiki Sawa, Yong Chen, Li Liu
Publikováno v:
Stem Cell Reports, Vol 9, Iss 5, Pp 1546-1559 (2017)
Summary: High-purity cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSCs) are promising for drug development and myocardial regeneration. However, most hiPSC-derived CMs morphologically and functionally resemble immature ra
Externí odkaz:
https://doaj.org/article/66b39ba0bb4a435b98ea2d6be99f8a63
Autor:
Tatsuki Ogasawara, Satomi Okano, Hajime Ichimura, Shin Kadota, Yuki Tanaka, Itsunari Minami, Motonari Uesugi, Yuko Wada, Naoto Saito, Kenji Okada, Koichiro Kuwahara, Yuji Shiba
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Pluripotent stem cell-derived cardiomyocytes show great promise in regenerating the heart after myocardial infarction; however, several uncertainties exist that must be addressed before clinical trials. One practical issue is graft survival
Externí odkaz:
https://doaj.org/article/93fb020c748746f585e41a522d5a3a4e
Autor:
Takahiro Takeuchi, MD, Takeshi Tomita, MD, PhD, Hiroki Kasai, MD, PhD, Daisuke Kashiwagi, MD, Koji Yoshie, MD, Tomonori Yaguchi, MD, Yasutaka Oguchi, MD, Ayako Kozuka, MD, Milan Gautam, MD, Hirohiko Motoki, MD, PhD, Ayako Okada, MD, Yuji Shiba, MD, PhD, Kazunori Aizawa, MD, PhD, Atsushi Izawa, MD, PhD, Yusuke Miyashita, MD, PhD, Jun Koyama, MD, PhD, Minoru Hongo, MD, PhD, Uichi Ikeda, MD, PhD
Publikováno v:
Journal of Arrhythmia, Vol 31, Iss 1, Pp 50-54 (2015)
A 15-year-old asymptomatic male patient presented with an electrocardiographic abnormality and left ventricular (LV) dysfunction (left ventricle ejection fraction of 40%) in a physical examination performed 2 years previously. LV dysfunction did not
Externí odkaz:
https://doaj.org/article/f313658071784b15a3578ce6825fe33e
Autor:
Milan Gautam, Atsushi Izawa, Yuji Shiba, Hirohiko Motoki, Takahiro Takeuchi, Ayako Okada, Takeshi Tomita, Yusuke Miyashita, Jun Koyama, Uichi Ikeda
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107003 (2014)
Importance of fatty acid components and imbalances has emerged in coronary heart disease. In this study, we analyzed fatty acids and ankle-brachial index (ABI) in a Japanese cohort.Peripheral arterial disease (PAD) was diagnosed in 101 patients by AB
Externí odkaz:
https://doaj.org/article/ec75374cdf704aa79e1b9b33eba8a18c
Autor:
Yuichiro Kashima, Masafumi Takahashi, Yuji Shiba, Naoki Itano, Atsushi Izawa, Jun Koyama, Jun Nakayama, Shun'ichiro Taniguchi, Koji Kimata, Uichi Ikeda
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58760 (2013)
Hyaluronan (HA) is a primary component of the extracellular matrix of cells, and it is involved in the pathogenesis of atherosclerosis. The purpose of this study was to investigate the role of HA in neointimal formation after vascular injury and dete
Externí odkaz:
https://doaj.org/article/ad04a4903e2b4544836cbf7242654bfd
Publikováno v:
Heart, Lung and Circulation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cd75aea46970738f1e4781a822c3f88
https://doi.org/10.1016/j.hlc.2022.12.014
https://doi.org/10.1016/j.hlc.2022.12.014
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627716
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83d584a8972ac3191792f8fb2ab1d3eb
https://doi.org/10.1007/978-1-0716-2772-3_8
https://doi.org/10.1007/978-1-0716-2772-3_8
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2587
Induced pluripotent stem cell (iPSC)-based disease model is a useful tool that can represent the pathophysiology of patient organs that are inaccessible due to invasiveness. Here, we present a method to induce differentiation of Duchenne muscular dys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7556a14a232308723d4c2b3f37841e8d
https://pubmed.ncbi.nlm.nih.gov/36401028
https://pubmed.ncbi.nlm.nih.gov/36401028