Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Yuji Nakai"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15771 (2022)
Skeletal muscle is programmable, and early-life nutritional stimuli may form epigenetic memory in the skeletal muscle, thus impacting adult muscle function, aging, and longevity. In the present study, we designed a one-month protein restriction model
Externí odkaz:
https://doaj.org/article/dbb3e3c07dc4406bb2e21af91f2eb408
Autor:
Shunsuke Kuroki, Yuji Nakai, Ryo Maeda, Naoki Okashita, Mika Akiyoshi, Yutaro Yamaguchi, Satsuki Kitano, Hitoshi Miyachi, Ryuichiro Nakato, Kenji Ichiyanagi, Katsuhiko Shirahige, Hiroshi Kimura, Yoichi Shinkai, Makoto Tachibana
Publikováno v:
Stem Cell Reports, Vol 10, Iss 4, Pp 1340-1354 (2018)
Summary: Histone H3 lysine 9 (H3K9) methylation is unevenly distributed in mammalian chromosomes. However, the molecular mechanism controlling the uneven distribution and its biological significance remain to be elucidated. Here, we show that JMJD1A
Externí odkaz:
https://doaj.org/article/873a67a4ed0542c7beb080526a64f47b
Autor:
Min Li, Yasunari Kanda, Takashi Ashihara, Tetsuo Sasano, Yuji Nakai, Masami Kodama, Erina Hayashi, Yuko Sekino, Tetsushi Furukawa, Junko Kurokawa
Publikováno v:
Journal of Pharmacological Sciences, Vol 134, Iss 2, Pp 75-85 (2017)
Human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes hold great potentials to predict pro-arrhythmic risks in preclinical cardiac safety screening, although the hiPSC cardiomyocytes exhibit rather immature functional and structural char
Externí odkaz:
https://doaj.org/article/07aceca9b16b42c88b263a8e009073ce
Autor:
Tomohisa Takagi, Ryotaro Hayashi, Yuji Nakai, Shinji Okada, Rumiko Miyashita, Mayumi Yamada, Yoichi Mihara, Katsura Mizushima, Mayuko Morita, Kazuhiko Uchiyama, Yuji Naito, Yoshito Itoh
Publikováno v:
Nutrients, Vol 12, Iss 8, p 2342 (2020)
Metabolic syndrome, whose main diagnostic component is obesity, is a risk factor for lifestyle-related diseases, type 2 diabetes, and cardiovascular disease. Diet is known to affect the prevalence of metabolic syndrome. However, the effect of diet on
Externí odkaz:
https://doaj.org/article/f976df9ab905475f9da9f7c2e02cb915
Autor:
Daiki Tatsumi, Yohei Hayashi, Mai Endo, Hisato Kobayashi, Takumi Yoshioka, Kohei Kiso, Shinichiro Kanno, Yuji Nakai, Ikuma Maeda, Kentaro Mochizuki, Makoto Tachibana, Haruhiko Koseki, Akihiko Okuda, Akira Yasui, Tomohiro Kono, Yasuhisa Matsui
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0205969 (2018)
In embryonic stem cells (ESCs), the expression of development-related genes, including germ cell-related genes, is globally repressed. The transcription factor MAX represses germ cell-related gene expression in ESCs via PCGF6-polycomb repressive comp
Externí odkaz:
https://doaj.org/article/06d8cb2fe8c14a6498ce1eba3fdbfc27
Autor:
Masashi Taniguchi, Kyoko Fujiwara, Yuji Nakai, Toshinori Ozaki, Nobuko Koshikawa, Kojima Toshio, Motoaki Kataba, Asako Oguni, Hiroyuki Matsuda, Yukihiro Yoshida, Yasuaki Tokuhashi, Noboru Fukuda, Takahiro Ueno, Masayoshi Soma, Hiroki Nagase
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 328-334 (2014)
Gene amplification and/or overexpression of the transcription factor c-MYC, which binds to the E-box sequence (5′-CACGTG-3′), has been observed in many human tumors. In this study, we have designed 5 pyrrole–imidazole (PI) polyamides recognizin
Externí odkaz:
https://doaj.org/article/72b591c7377049c69ef82b9190acfce0
Autor:
Hiroaki Kanouchi, Toshiaki Kakimoto, Hideya Nakano, Masahiro Suzuki, Yuji Nakai, Kazuhiro Shiozaki, Kohei Akikoka, Konosuke Otomaru, Masanobu Nagano, Mitsuharu Matsumoto
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150796 (2016)
Kurozu is a traditional Japanese rice vinegar. During fermentation and aging of the Kurozu liquid in an earthenware jar over 1 year, a solid residue called Kurozu Moromi is produced. In the present study, we evaluated whether concentrated Kurozu or K
Externí odkaz:
https://doaj.org/article/0c97ca9a71b64ab992f02152e777f85c
Autor:
Sunwoo Chun, Takeshi Bamba, Tatsuya Suyama, Tomoko Ishijima, Eiichiro Fukusaki, Keiko Abe, Yuji Nakai
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155386 (2016)
A high phosphorus (HP) diet causes disorders of renal function, bone metabolism, and vascular function. We previously demonstrated that DNA microarray analysis is an appropriate method to comprehensively evaluate the effects of a HP diet on kidney dy
Externí odkaz:
https://doaj.org/article/2ccf9afb40f54e59a806f4bbcb9b7ca5
Autor:
Asuka Kamei, Yuki Watanabe, Kaori Kondo, Shinji Okada, Fumika Shinozaki, Tomoko Ishijima, Yuji Nakai, Takashi Kondo, Soichi Arai, Keiko Abe
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65732 (2013)
Iron is an essential mineral for the body, and iron deficiency generally leads to anemia. However, because non-anemic iron deficiency can exist, we performed a comprehensive transcriptome analysis of the liver to define the effects of this condition
Externí odkaz:
https://doaj.org/article/a449ef78b6604d3ca2bd919e4278e67f
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29483 (2012)
The mechanism by which phosphorus levels are maintained in the body was investigated by analyzing changes in gene expression in the rat kidney following administration of a high phosphorus (HP) diet. Male Wistar rats were divided into two groups and
Externí odkaz:
https://doaj.org/article/7c630e0197de4b7e87fa70306d466304