Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Yuji Nakada"'
Autor:
Yongyu Wang, Yalin Wu, Yu Jiang, Huilan Tan, Bijay Guragain, Thanh Nguyen, Jianli Zhao, Yang Zhou, Yuji Nakada, Jianyi Zhang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 21 (2024)
Background The proliferative capacity of cardiomyocytes in adult mammalian hearts is far too low to replace the cells that are lost to myocardial infarction. Both cardiomyocyte proliferation and myocardial regeneration can be improved via the overexp
Externí odkaz:
https://doaj.org/article/fcd71701b39843e39425bc0deb830655
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/e9b2ce1a321b4d41ad23b7f178aeab66
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Single-cell RNA sequencing (scRNAseq) enables researchers to identify and characterize populations and subpopulations of different cell types in hearts recovering from myocardial infarction (MI) by characterizing the transcriptomes in thousa
Externí odkaz:
https://doaj.org/article/970bfb635c78409da10f40be38268f46
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Adult mammalian cardiomyocytes have very limited capacity to proliferate and repair the myocardial infarction. However, when apical resection (AR) was performed in pig hearts on postnatal day (P) 1 (ARP1) and acute myocardial infarction (MI) was indu
Externí odkaz:
https://doaj.org/article/8b7ff3f997064591aa27f5e09b6959d3
Autor:
Asher Kahn-Krell, Danielle Pretorius, Bijay Guragain, Xi Lou, Yuhua Wei, Jianhua Zhang, Aijun Qiao, Yuji Nakada, Timothy J. Kamp, Lei Ye, Jianyi Zhang
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Cardiomyocytes (CMs), endothelial cells (ECs), smooth-muscle cells (SMCs), and cardiac fibroblasts (CFs) differentiated from human induced-pluripotent stem cells (hiPSCs) are the fundamental components of cell-based regenerative myocardial therapy an
Externí odkaz:
https://doaj.org/article/c06b22d6dfaf417fa9a97c9a12c30989
Publikováno v:
JCI Insight, Vol 6, Iss 20 (2021)
The meager regenerative capacity of adult mammalian hearts appears to be driven by the proliferation of endogenous cardiomyocytes; thus, strategies targeting mechanisms of cardiomyocyte cell cycle regulation, such as the Hippo/Yes-associated protein
Externí odkaz:
https://doaj.org/article/5757b97997e84a04b40e90b1cc42617f
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 2 (2021)
Abstract The failure of adult cardiomyocytes to reproduce themselves to repair an injury results in the development of severe cardiac disability leading to death in many cases. The quest for an understanding of the inability of cardiac myocytes to re
Externí odkaz:
https://doaj.org/article/af6c9e362abf46bbb6e2c9361d147253
Publikováno v:
Molecules, Vol 27, Iss 10, p 3259 (2022)
In retronasal aroma, the targeted aroma compounds are released from food during chewing. The changes in the food structures during chewing strongly influence the release of the compounds, therefore affecting the perception of food. Here, the relation
Externí odkaz:
https://doaj.org/article/7b53b50d24924ea986e303e26b85d810
Autor:
Yuji Nakada, Thomas G Stewart, Christopher G Peña, Song Zhang, Ni Zhao, Nabeel Bardeesy, Norman E Sharpless, Kwok-Kin Wong, D Neil Hayes, Diego H Castrillon
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73449 (2013)
Germline mutations in the LKB1 gene (also known as STK11) cause the Peutz-Jeghers Syndrome, and somatic loss of LKB1 has emerged as causal event in a wide range of human malignancies, including melanoma, lung cancer, and cervical cancer. The LKB1 pro
Externí odkaz:
https://doaj.org/article/6a00581d51954764bdb5a069e774041d
Autor:
Yuji Nakada, Yang Zhou, Wuming Gong, Eric Y. Zhang, Erik Skie, Thanh Nguyen, Yuhua Wei, Meng Zhao, Wangping Chen, Jiacheng Sun, S. Naqi Raza, Jake Y. Chen, Gregory P. Walcott, Daniel J. Garry, Jianyi (Jay) Zhang
Publikováno v:
Circulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e44c98c4a5f4503c82b734e36d6533
https://pubmed.ncbi.nlm.nih.gov/35666813
https://pubmed.ncbi.nlm.nih.gov/35666813