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Akademický článek
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Autor:
Yukihiro Imaoka, Nice Ren, Soshiro Ogata, Hirotoshi Imamura, Yasuyuki Kaku, Koichi Arimura, Shogo Watanabe, Eri Kiyoshige, Kunihiro Nishimura, Syoji Kobashi, Masafumi Ihara, Kenji Kamiyama, Masafumi Morimoto, Tsuyoshi Ohta, Hidenori Endo, Yuji Matsumaru, Nobuyuki Sakai, Takanari Kitazono, Shigeru Fujimoto, Kuniaki Ogasawara, Koji Iihara, Close The Gap‐Stroke, J‐ASPECT Study Collaborators
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 12, Pp 3103-3114 (2024)
Abstract Objective We evaluated the effect of CHA2DS2‐VASc score and prior use of oral anticoagulants (OACs) on endovascular treatment (EVT) in patients with acute ischemic stroke and atrial fibrillation (AF). Methods Patients with AF who received
Externí odkaz:
https://doaj.org/article/54881ecce0194050964c395a316e748b
Autor:
Yoshiteru Takekita, Yuji Matsumoto, Takahiro Masuda, Kazumasa Yoshida, Yosuke Koshikawa, Masaki Kato
Publikováno v:
Neuropsychopharmacology Reports, Vol 44, Iss 4, Pp 784-791 (2024)
Abstract Aim To explore the optimal dose of blonanserin transdermal patch (BNS‐P) based on baseline psychiatric symptomatic characteristics during acute schizophrenia. Methods A post hoc cluster analysis was conducted using data from a 6‐week ran
Externí odkaz:
https://doaj.org/article/a152ec6793624020b2f4cca49e0a96c9
Autor:
Satoru FUJIWARA, Akira ISHII, Tsuyoshi OHTA, Nobuyuki OHARA, Michi KAWAMOTO, Koji IIHARA, Hirotoshi IMAMURA, Yuji MATSUMARU, Chiaki SAKAI, Tetsu SATOW, Shinichi YOSHIMURA, Nobuyuki SAKAI, Japanese Registry of Neuroendovascular Therapy (JR-NET) Investigators
Publikováno v:
Neurologia Medico-Chirurgica, Vol 64, Iss 11, Pp 387-394 (2024)
Endovascular treatment (EVT) is a potential therapeutic option for extracranial vertebral artery (VA) stenosis; however, its efficacy or optimal procedures remain unknown. This study aimed to investigate the recent status of EVT for extracranial VA s
Externí odkaz:
https://doaj.org/article/57729596eea547568037bbfa45086817
Autor:
Naonori Kumagai, Hiroki Takao, Yuta Sudo, Masatoshi Yoshikane, Tomomi Kondoh, Yuji Matsumoto, Haruo Mizuno, Michiaki Abe, Yohei Ikezumi
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 16, Iss 1, Pp 1-9 (2024)
Abstract Background Proximal renal tubular dysfunction occurs during diabetic ketoacidosis (DKA) in type 1 diabetes. However, only a few studies have reported on the multiple proximal renal tubular functions simultaneously. Moreover, to the best of o
Externí odkaz:
https://doaj.org/article/5bcdda36f75349e09fa9adaa1fd8201f
Autor:
Yuhei Waki, Yuji Morine, Yu Saito, Hiroki Teraoku, Shinichiro Yamada, Tetsuya Ikemoto, Tatsuya Tominaga, Mitsuo Shimada
Publikováno v:
Annals of Gastroenterological Surgery, Vol 8, Iss 6, Pp 1084-1095 (2024)
Abstract Background The interactions between cancer cells and tumor‐associated macrophages (TAMs) via microRNAs (miRNAs) play crucial roles in malignant potential and drug resistance. However, it remains unclear how lenvatinib‐resistant hepatocel
Externí odkaz:
https://doaj.org/article/fdb57b104988492b87fbbad8a768ff6e
Autor:
Darrin D. Stuart, William R. Sellers, Savithri Ramurthy, Emma Lees, Michael P. Dillon, Nicholas Keen, Mallika Singh, Payman Amiri, Mohammad Hekmat-Nejad, Richard Zang, Valery Polyakov, Robert Aversa, Jacob R. Haling, John Tellew, Alice Rico, Gisele Nishiguchi, Lesley A. Mathews Griner, Joshua M. Korn, Fang Shen, Yingyun Wang, Stacy Rivera, Vesselina G. Cooke, Giordano Caponigro, Yun Feng, Yuji M. Mishina, Wenlin Shao
Antiproliferative effect of RAF709 compared to dabrafenib, trametinib, RAF265 and sorafenib across a tumor cell panel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df399afb7bc4b33e7cbabf7feb9002be
https://doi.org/10.1158/0008-5472.22417724
https://doi.org/10.1158/0008-5472.22417724
Autor:
Darrin D. Stuart, William R. Sellers, Savithri Ramurthy, Emma Lees, Michael P. Dillon, Nicholas Keen, Mallika Singh, Payman Amiri, Mohammad Hekmat-Nejad, Richard Zang, Valery Polyakov, Robert Aversa, Jacob R. Haling, John Tellew, Alice Rico, Gisele Nishiguchi, Lesley A. Mathews Griner, Joshua M. Korn, Fang Shen, Yingyun Wang, Stacy Rivera, Vesselina G. Cooke, Giordano Caponigro, Yun Feng, Yuji M. Mishina, Wenlin Shao
Legends for supplemental figures and tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ecd2476f2638a45906022d87ad08b63
https://doi.org/10.1158/0008-5472.22417733.v1
https://doi.org/10.1158/0008-5472.22417733.v1
Autor:
Darrin D. Stuart, William R. Sellers, Savithri Ramurthy, Emma Lees, Michael P. Dillon, Nicholas Keen, Mallika Singh, Payman Amiri, Mohammad Hekmat-Nejad, Richard Zang, Valery Polyakov, Robert Aversa, Jacob R. Haling, John Tellew, Alice Rico, Gisele Nishiguchi, Lesley A. Mathews Griner, Joshua M. Korn, Fang Shen, Yingyun Wang, Stacy Rivera, Vesselina G. Cooke, Giordano Caponigro, Yun Feng, Yuji M. Mishina, Wenlin Shao
Table S1: Kinase hits from KinomeScan panel. Table S4: Antiproliferative activity of RAF709 in a Ba/F3 cell kinase panel.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1dd2a0d5312e56631333a731f162e6
https://doi.org/10.1158/0008-5472.22417721.v1
https://doi.org/10.1158/0008-5472.22417721.v1
Autor:
Darrin D. Stuart, William R. Sellers, Savithri Ramurthy, Emma Lees, Michael P. Dillon, Nicholas Keen, Mallika Singh, Payman Amiri, Mohammad Hekmat-Nejad, Richard Zang, Valery Polyakov, Robert Aversa, Jacob R. Haling, John Tellew, Alice Rico, Gisele Nishiguchi, Lesley A. Mathews Griner, Joshua M. Korn, Fang Shen, Yingyun Wang, Stacy Rivera, Vesselina G. Cooke, Giordano Caponigro, Yun Feng, Yuji M. Mishina, Wenlin Shao
Resistance to the RAF inhibitor vemurafenib arises commonly in melanomas driven by the activated BRAF oncogene. Here, we report antitumor properties of RAF709, a novel ATP-competitive kinase inhibitor with high potency and selectivity against RAF kin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b65b9e42831ecdc7ded906b41fb312
https://doi.org/10.1158/0008-5472.c.6509918
https://doi.org/10.1158/0008-5472.c.6509918