Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Yuji Kurihara"'
Publikováno v:
Cells, Vol 13, Iss 16, p 1369 (2024)
Neurite outgrowth is a crucial process for organizing neuronal circuits in neuronal development and regeneration after injury. Regenerative failure in the adult mammalian central nervous system (CNS) is attributed to axonal growth inhibitors such as
Externí odkaz:
https://doaj.org/article/21a53092765d49f1829a0cfabe8cb85a
Autor:
Yuji Kurihara, Kotone Mitsunari, Nagi Mukae, Hirotaka Shoji, Tsuyoshi Miyakawa, Michiko Shirane
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-18 (2023)
Abstract Although dyslipidemia in the brain has been implicated in neurodegenerative disorders, the molecular mechanisms underlying its pathogenesis have been largely unclear. PDZD8 is a lipid transfer protein and mice deficient in PDZD8 (PDZD8-KO mi
Externí odkaz:
https://doaj.org/article/1cec2d0dedba4c3c9e50a938a7991478
Autor:
Yuki Kawaguchi, Junpei Matsubayashi, Yutaka Kawakami, Ryohei Nishida, Yuji Kurihara, Kohtaro Takei
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-13 (2022)
Abstract Background Alzheimer’s disease (AD) is the most common neurodegenerative disease worldwide but has no effective treatment. Amyloid beta (Aβ) protein, a primary risk factor for AD, accumulates and aggregates in the brain of patients with A
Externí odkaz:
https://doaj.org/article/48f01a0cce6b4ca8bd522ad02c01bcd8
Autor:
Keisuke Mishima, Takeshi Matsutani, Ryo Yamagiwa, Hidetsugu Hanawa, Yuji Kurihara, Norio Motoda, Nobuhiko Taniai, Hiroshi Yoshida
Publikováno v:
Surgical Case Reports, Vol 8, Iss 1, Pp 1-6 (2022)
Abstract Background Esophageal gastrointestinal stromal tumors (E-GISTs) are often diagnosed early due to complaints such as dysphagia and are rarely found to be huge in size. Here, we report the treatment of a case of huge E-GIST successfully resect
Externí odkaz:
https://doaj.org/article/b42820d8c97c43bcbef2544782e54971
Publikováno v:
Clinical and Experimental Dental Research, Vol 7, Iss 4, Pp 484-489 (2021)
Abstract Background Few reports have examined dental arch morphology (DAM) after dental implant placement in cleft patients and its actual state is unclear. Objective To analyze the presence of changes in DAM and influencing factors in cleft lip and/
Externí odkaz:
https://doaj.org/article/49ea21c12d8e4aa4950b3c4b1de19e1c
Autor:
Kazunori Utsunomiya, Ryusuke Koshida, Seigo Kakiuchi, Masayuki Senda, Shoko Fujii, Yuji Kurihara, Ryoji Gunji, Kohei Kaku
Publikováno v:
Journal of Diabetes Investigation, Vol 12, Iss 2, Pp 184-199 (2021)
Abstract Aims/Introduction Tofogliflozin is a sodium–glucose cotransporter 2 (SGLT2) inhibitor that lowers plasma glucose levels by enhancing urinary glucose excretion. After its approval in Japan in 2014 for the treatment of type 2 diabetes mellit
Externí odkaz:
https://doaj.org/article/f5d8d3d14e704c9da6e44e7af5ba7a09
Autor:
Kazunori Utsunomiya, Seigo Kakiuchi, Masayuki Senda, Shoko Fujii, Yuji Kurihara, Ryoji Gunji, Ryusuke Koshida, Hiroyuki Kameda, Masahiro Tamura, Kohei Kaku
Publikováno v:
Journal of Diabetes Investigation, Vol 11, Iss 4, Pp 906-916 (2020)
Abstract Aims/Introduction Tofogliflozin is a potent and highly selective sodium–glucose cotransporter 2 inhibitor, and is currently used to treat patients with type 2 diabetes mellitus. We designed a 3‐year study of tofogliflozin in patients wit
Externí odkaz:
https://doaj.org/article/b18f448e112b4bacbd199cd11f9b4f66
Autor:
Kohei Kaku, Yusuke Naito, Masayuki Senda, Yuji Kurihara, Ryoji Gunji, Seigo Kakiuchi, Kazunori Utsunomiya
Publikováno v:
Journal of Diabetes Investigation, Vol 11, Iss 2, Pp 405-416 (2020)
Abstract Aims/Introduction This subanalysis aimed to assess the safety and effectiveness of tofogliflozin by using data from the Japanese Study of Tofogliflozin with Type 2 Diabetes Mellitus Patients in an Observational Study of the Elderly to catego
Externí odkaz:
https://doaj.org/article/a481c72f9f974974b873b8ec465e8b52
Autor:
Kazunori Utsunomiya, Masayuki Senda, Seigo Kakiuchi, Hiroyuki Kameda, Masahiro Tamura, Yuji Kurihara, Ryoji Gunji, Shoko Fujii, Kohei Kaku
Publikováno v:
Journal of Diabetes Investigation, Vol 11, Iss 1, Pp 132-141 (2020)
Abstract Aims/Introduction Due to the paucity of tofogliflozin data, we assessed the safety and effectiveness of tofogliflozin among Japanese patients with type 2 diabetes mellitus in the clinical setting, stratifying the patients by age, sex, estima
Externí odkaz:
https://doaj.org/article/1cead48cc96c427f893bb884e3bc21ff
Autor:
Yasuo Terauchi, Hisataka Fujiwara, Yuji Kurihara, Hideki Suganami, Masahiro Tamura, Masayuki Senda, Ryoji Gunji, Kohei Kaku
Publikováno v:
Journal of Diabetes Investigation, Vol 10, Iss 6, Pp 1518-1526 (2019)
Abstract Aims/Introduction Tofogliflozin is a potent and highly selective sodium–glucose cotransporter 2 inhibitor that is currently used to treat patients with type 2 diabetes mellitus. The aim of the present study was to evaluate the safety and e
Externí odkaz:
https://doaj.org/article/5bfd573105c6495d9a9b2340320100d7