Intracellular Mg2+ protects mitochondria from oxidative stress in human keratinocytes

Autor: Keigo Fujita, Yutaka Shindo, Yuji Katsuta, Makiko Goto, Kohji Hotta, Kotaro Oka

Publikováno v: Communications Biology, Vol 6, Iss 1, Pp 1-9 (2023)

Abstract Reactive oxygen species (ROS) are harmful for the human body, and exposure to ultraviolet irradiation triggers ROS generation. Previous studies have demonstrated that ROS decrease mitochondrial membrane potential (MMP) and that Mg2+ protects

Externí odkaz: https://doaj.org/article/b78abe5be1fd43dfb73b0c552dd79c9a

Elevation of Hyaluronan Synthase by Magnesium Supplementation Mediated through the Activation of GSK3 and CREB in Human Keratinocyte-Derived HaCaT Cells

Autor: Kana Marunaka, Shokoku Shu, Mao Kobayashi, Makiko Goto, Yuji Katsuta, Yuta Yoshino, Akira Ikari

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 71, p 71 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 71

Skin barrier damage is present in the patients with hereditary disorders of the magnesium channel, but the molecular mechanism has not been fully understood. We found that the expressions of hyaluronan synthase (HAS), HAS2 and HAS3 are influenced by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596fd5013e1ea6843542a3e725e133a0
https://www.mdpi.com/1422-0067/23/1/71

Effect of temperature on the expression of redox genes in human dermal fibroblasts

Autor: Yuji Katsuta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::da69bfdc5dcc2218009930ffa81750b8
https://doi.org/10.26226/morressier.595a9c58d462b80296ca0090

Fibulin-5 accelerates elastic fibre assembly in human skin fibroblasts

Autor: Satoshi Amano, Paul F. Goetinck, Yuji Katsuta, John F. Klement, Jouni Uitto, Yuki Ogura, Shunsuke Iriyama

Publikováno v: Experimental Dermatology. 17:837-842

Fibulin-5 null mice display abnormalities in the elastic fibres in the dermis. We postulated, therefore, that fibulin-5 might be a regulator of elastic fibre assembly and stability. To clarify the role of fibulin-5 in elastic fibre formation, we empl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb0fe43334996de669fe446fe578ca5
https://doi.org/10.1111/j.1600-0625.2008.00709.x

Kaempferol Enhanced the Intracellular Thioredoxin System in Normal Cultured Human Keratinocytes

Autor: Jotaro Nakanishi, Yuji Katsuta, Misato Sugahara

Publikováno v: Bioscience, Biotechnology, and Biochemistry. 74:1701-1703

The effects of kaempferol on redox-associated enzymes in normal human keratinocytes were studied. It enhanced the gene expression of thioredoxin reductase 1 and thioredoxin. Flavonols had higher ability to induce the expression of these genes than th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff4dcce24910a50d39365abb579c524
https://doi.org/10.1271/bbb.100166