Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Yuji IWASHITA"'
Autor:
Augustin Nzitakera, Jean Bosco Surwumwe, Ella Larissa Ndoricyimpaye, Schifra Uwamungu, Delphine Uwamariya, Felix Manirakiza, Marie Claire Ndayisaba, Gervais Ntakirutimana, Benoit Seminega, Vincent Dusabejambo, Eric Rutaganda, Placide Kamali, François Ngabonziza, Rei Ishikawa, Belson Rugwizangoga, Yuji Iwashita, Hidetaka Yamada, Kimio Yoshimura, Haruhiko Sugimura, Kazuya Shinmura
Publikováno v:
Genes and Environment, Vol 46, Iss 1, Pp 1-16 (2024)
Abstract Background Gastric cancer is the sixth most frequently diagnosed cancer and third in causing cancer-related death globally. The most frequently mutated gene in human cancers is TP53, which plays a pivotal role in cancer initiation and progre
Externí odkaz:
https://doaj.org/article/ec91c9212ec340219232c4764b265bf0
Autor:
De Hu, Hidetaka Yamada, Katsuhiro Yoshimura, Tsutomu Ohta, Kazuo Tsuchiya, Yusuke Inoue, Kazuhito Funai, Takafumi Suda, Yuji Iwashita, Takuya Watanabe, Hiroshi Ogawa, Nobuhito Kurono, Kazuya Shinmura, Haruhiko Sugimura
Publikováno v:
Current Oncology, Vol 30, Iss 11, Pp 9484-9500 (2023)
Fas-associated factor 1 (FAF1) is a death-promoting protein identified as an interaction partner of the death receptor Fas. The downregulation and mutation of FAF1 have been reported in a variety of human tumors, but there have been few studies on lu
Externí odkaz:
https://doaj.org/article/bdc79a6c628840ae8d83348f7fc3c50b
Autor:
Felix Manirakiza, Hidetaka Yamada, Yuji Iwashita, Keiko Ishino, Rei Ishikawa, Zsolt Kovacs, Eva Osvath, Augustin Nzitakera, Simona Gurzu, Haruhiko Sugimura
Publikováno v:
Genes and Environment, Vol 45, Iss 1, Pp 1-8 (2023)
Abstract Background Colorectal cancer (CRC) has been ranked as the second most deadly cancer and the third most diagnosed cancer cases for the year 2020. Specifically for Romania, the number of CRC-related deaths in 2019 was estimated at 6307 people,
Externí odkaz:
https://doaj.org/article/80f2bb0820d346caa3b90c0f20a6f8e2
Autor:
Felix Manirakiza, Eric Rutaganda, Hidetaka Yamada, Yuji Iwashita, Belson Rugwizangoga, Benoit Seminega, Vincent Dusabejambo, Gervais Ntakirutimana, Deogratias Ruhangaza, Annette Uwineza, Kazuya Shinmura, Haruhiko Sugimura
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 5, Pp 4359-4374 (2023)
Cancer research in Rwanda is estimated to be less than 1% of the total African cancer research output with limited research on colorectal cancer (CRC). Rwandan patients with CRC are young, with more females being affected than males, and most patient
Externí odkaz:
https://doaj.org/article/c85d6dba9b1245f4ac5eb16752b358ff
Autor:
Augustin Nzitakera, Jean Bosco Surwumwe, Ella Larissa Ndoricyimpaye, Schifra Uwamungu, Delphine Uwamariya, Felix Manirakiza, Marie Claire Ndayisaba, Gervais Ntakirutimana, Benoit Seminega, Vincent Dusabejambo, Eric Rutaganda, Placide Kamali, François Ngabonziza, Rei Ishikawa, Belson Rugwizangoga, Yuji Iwashita, Hidetaka Yamada, Kimio Yoshimura, Haruhiko Sugimura, Kazuya Shinmura
Publikováno v:
Genes and Environment, Vol 46, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/f5b6d16c85d74526962d03b1daa517b9
Autor:
Hiroko Natsume, Kinga Szczepaniak, Hidetaka Yamada, Yuji Iwashita, Marta Gędek, Jelena Šuto, Keiko Ishino, Rika Kasajima, Tomonari Matsuda, Felix Manirakiza, Augustin Nzitakera, Yijia Wu, Nong Xiao, Qiong He, Wenwen Guo, Zhenming Cai, Tsutomu Ohta, Tıberiu Szekely, Zoltan Kadar, Akiko Sekiyama, Takashi Oshima, Takaki Yoshikawa, Akira Tsuburaya, Nobuhito Kurono, Yaping Wang, Yohei Miyagi, Simona Gurzu, Haruhiko Sugimura
Publikováno v:
Genes and Environment, Vol 45, Iss 1, Pp 1-13 (2023)
Abstract Aim Mutation spectrum of TP53 in gastric cancer (GC) has been investigated world-widely, but a comparison of mutation spectrum among GCs from various regions in the world are still sparsely documented. In order to identify the difference of
Externí odkaz:
https://doaj.org/article/cbf4ee58a8bd45a5ab90f396841a9a36
Autor:
Yuto Matsushita, Yuji Iwashita, Shunsuke Ohtsuka, Ippei Ohnishi, Takashi Yamashita, Hideaki Miyake, Haruhiko Sugimura
Publikováno v:
Genes and Environment, Vol 43, Iss 1, Pp 1-14 (2021)
Abstract Background DNA adducts, covalent modifications to DNA due to exposure to specific carcinogens, cause the mispairing of DNA bases, which ultimately results in DNA mutations. DNA methylation in the promoter region, another type of DNA base mod
Externí odkaz:
https://doaj.org/article/fb0898992ccc409bba965536dc3ca1d4
Autor:
Yuta Tsunematsu, Koji Hosomi, Jun Kunisawa, Michio Sato, Noriko Shibuya, Emiko Saito, Haruka Murakami, Yuko Yoshikawa, Yuji Iwashita, Noriyuki Miyoshi, Michihiro Mutoh, Hideki Ishikawa, Haruhiko Sugimura, Motohiko Miyachi, Keiji Wakabayashi, Kenji Watanabe
Publikováno v:
BMC Microbiology, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Background The Escherichia coli strain that is known to produce the genotoxic secondary metabolite colibactin is linked to colorectal oncogenesis. Therefore, understanding the properties of such colibactin-positive E. coli and the molecular
Externí odkaz:
https://doaj.org/article/ad0699ae8e25497e8ceae1f4381c0e95
Autor:
Ippei Ohnishi, Yuji Iwashita, Yuto Matsushita, Shunsuke Ohtsuka, Takashi Yamashita, Keisuke Inaba, Atsuko Fukazawa, Hideto Ochiai, Keigo Matsumoto, Nobuhito Kurono, Yoshitaka Matsushima, Hiroki Mori, Shioto Suzuki, Shohachi Suzuki, Fumihiko Tanioka, Haruhiko Sugimura
Publikováno v:
Genes and Environment, Vol 43, Iss 1, Pp 1-13 (2021)
Abstract Background A comprehensive understanding of DNA adducts, one of the most plausible origins of cancer mutations, is still elusive, especially in human tissues in clinical settings. Recent technological developments have facilitated the identi
Externí odkaz:
https://doaj.org/article/ddd4e21bbe964e13bed448c0e7778f0d
Autor:
Masanobu Kawanishi, Chiaki Shimohara, Yoshimitsu Oda, Yuuta Hisatomi, Yuta Tsunematsu, Michio Sato, Yuichiro Hirayama, Noriyuki Miyoshi, Yuji Iwashita, Yuko Yoshikawa, Haruhiko Sugimura, Michihiro Mutoh, Hideki Ishikawa, Keiji Wakabayashi, Takashi Yagi, Kenji Watanabe
Publikováno v:
Genes and Environment, Vol 42, Iss 1, Pp 1-6 (2020)
Abstract Introduction Colibactin is a small genotoxic molecule produced by enteric bacteria, including certain Escherichia coli (E. coli) strains harbored in the human large intestine. This polyketide-peptide genotoxin is considered to contribute to
Externí odkaz:
https://doaj.org/article/6496a12ac1ae42c187cc8a997a882d99