Zobrazeno 1 - 10
of 201
pro vyhledávání: '"Yuji C. SASAKI"'
Autor:
Daisuke Sasaki, Tatsuya Arai, Yue Yang, Masahiro Kuramochi, Wakako Furuyama, Asuka Nanbo, Hiroshi Sekiguchi, Nobuhiro Morone, Kazuhiro Mio, Yuji C. Sasaki
Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101712- (2024)
Single-molecule intramolecular dynamics were successfully measured for three variants of SARS-CoV-2 spike protein, alpha: B.1.1.7, delta: B.1.617, and omicron: B.1.1.529, with a time resolution of 100 μs using X-rays. The results were then compared
Externí odkaz:
https://doaj.org/article/e11640f8ec6b41749adcc6e2be830094
Autor:
Artoni Kevin R. Ang, Yasufumi Umena, Ayana Sato-Tomita, Naoya Shibayama, Naohisa Happo, Riho Marumi, Yuta Yamamoto, Koji Kimura, Naomi Kawamura, Yu Takano, Tomohiro Matsushita, Yuji C. Sasaki, Jian-Ren Shen, Kouichi Hayashi
Publikováno v:
Journal of Synchrotron Radiation, Vol 30, Iss 2, Pp 368-378 (2023)
X-ray fluorescence holography (XFH) is a powerful atomic resolution technique capable of directly imaging the local atomic structure around atoms of a target element within a material. Although it is theoretically possible to use XFH to study the loc
Externí odkaz:
https://doaj.org/article/04c7cbec2a3d47d0a2d93dbfe96f4b5b
Autor:
Kazuhiro Mio, Tatsunari Ohkubo, Daisuke Sasaki, Mayui Sugiura, Kayoko Kawaguchi, Kazutaka Araki, Keizaburo Taninaka, Masaki Sakaguchi, Shunsuke Nozawa, Tatsuya Arai, Yuji C. Sasaki
Publikováno v:
Membranes, Vol 14, Iss 4, p 75 (2024)
Protein dynamics play important roles in biological functions, which accompany allosteric structure changes. Diffracted X-ray blinking (DXB) uses monochromatic X-rays and nanocrystal probes. The intramolecular motion of target proteins is analyzed fr
Externí odkaz:
https://doaj.org/article/4338b407ac3f4b2b83dc2cf75de5ef2a
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Many psychrophilic microorganisms synthesize ice-binding proteins (IBPs) to survive the cold. The functions of IBPs are evaluated by the effect of the proteins on the nonequilibrium water freezing-point depression, which is called “thermal
Externí odkaz:
https://doaj.org/article/5552710c34c6481aad72fb0792671f7e
Autor:
Koichiro Saito, Kouhei Ichiyanagi, Ryo Fukaya, Rie Haruki, Shunsuke Nozawa, Daisuke Sasaki, Tatsuya Arai, Yuji C. Sasaki, Keegan McGehee, Makoto Saikawa, Minghao Gao, Zhichao Wei, Dennis Kwaria, Yasuo Norikane
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17462 (2023)
The photoinduced crawling motion of crystals is a continuous motion that azobenzene molecular crystals exhibit under light irradiation. Such motion enables object manipulation at the microscale with a simple setup of fixed LED light sources. Transpor
Externí odkaz:
https://doaj.org/article/d8965e1cd53c47fd8731b74e42a4c4fe
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 17083 (2023)
Ubiquitination is a process that dictates the lifespan of major histocompatibility complex class II (MHC II)/peptide complexes on antigen-presenting cells. This process is tightly controlled by the levels of ubiquitin ligases, and disruptions in the
Externí odkaz:
https://doaj.org/article/854d8be8dfa749779fd6608d7296d52a
Autor:
Tatsuya Arai, Kazuhiro Mio, Hiroki Onoda, Leonard M. G. Chavas, Yasufumi Umena, Yuji C. Sasaki
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16640 (2023)
X-ray crystallography has revolutionized our understanding of biological macromolecules by elucidating their three-dimensional structures. However, the use of X-rays in this technique raises concerns about potential damage to the protein crystals, wh
Externí odkaz:
https://doaj.org/article/cd14608226124dbbb454ae0afa096a9f
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16914 (2023)
Understanding the cellular environment as molecular crowding that supports the structure-specific functional expression of biomolecules has recently attracted much attention. Time-resolved X-ray observations have the remarkable capability to capture
Externí odkaz:
https://doaj.org/article/02f9a1ff570f42288366a3cf063c5bfb
Autor:
Tsutomu Yamane, Takahiro Nakayama, Toru Ekimoto, Masao Inoue, Keigo Ikezaki, Hiroshi Sekiguchi, Masahiro Kuramochi, Yasuo Terao, Ken Judai, Minoru Saito, Mitsunori Ikeguchi, Yuji C. Sasaki
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15423 (2023)
Tubulin has been recently reported to form a large family consisting of various gene isoforms; however, the differences in the molecular features of tubulin dimers composed of a combination of these isoforms remain unknown. Therefore, we attempted to
Externí odkaz:
https://doaj.org/article/736c0348e64e4bc4b0245f0be318acec
Autor:
Yuji C. Sasaki
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14829 (2023)
In 1998, the diffracted X-ray tracking (DXT) method pioneered the attainment of molecular dynamics measurements within individual molecules. This breakthrough revolutionized the field by enabling unprecedented insights into the complex workings of mo
Externí odkaz:
https://doaj.org/article/9ca31fe988eb4c37bfa57bb2be87a708