Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yuji, Shinjo"'
Autor:
Kumiko Makide, Akiharu Uwamizu, Yuji Shinjo, Jun Ishiguro, Michiyo Okutani, Asuka Inoue, Junken Aoki
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 10, Pp 1986-1995 (2014)
It is now accepted that lysophospholipids (LysoGPs) have a wide variety of functions as lipid mediators that are exerted through G protein-coupled receptors (GPCRs) specific to each lysophospholipid. While the roles of some LysoGPs, such as lysophosp
Externí odkaz:
https://doaj.org/article/f8a2f9bc42b445269164a929da1d1128
Autor:
Mohammad Amraei, Monique Lagacé, Jean-Michel Longpré, Viktoriya Lukasheva, Ryan D. Martin, Christian Le Gouill, Graciela Piñeyro, Dominic Devost, Yuji Shinjo, Stéphane A. Laporte, Junken Aoki, Billy Breton, Mireille Hogue, Michel Bouvier, Asuka Inoue, Yoon Namkung, Terence E. Hébert, Jason C. Tanny
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
A comprehensive understanding of signalling downstream of GPCRs requires a broad approach to capture novel signalling modalities in addition to established pathways. Here, using an array of sixteen validated BRET-based biosensors, we analyzed the abi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1089637a764ec4169b322941b3c13d
http://link.springer.com/article/10.1038/s41598-020-65636-3
http://link.springer.com/article/10.1038/s41598-020-65636-3
Autor:
Asuka Inoue, Yuko Otani, Keita Satoh, Junken Aoki, Yuji Shinjo, Kuniyuki Kano, Kumiko Makide, Fumiya Fukami, Tomohiko Ohwada
Publikováno v:
Biochemical and Biophysical Research Communications. 494:332-338
Lysophosphatidylserine (LysoPS) has been shown to have lipid mediator-like actions to induce mast cell degranulation and suppress T lymphocyte proliferation. Recently, three G protein-coupled receptors (GPCRs), LPS1/GPR34, LPS2/P2Y10, and LPS3/GPR174
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7507b4ff222a5adacc179b0a83376432
https://doi.org/10.1016/j.bbrc.2017.10.028
https://doi.org/10.1016/j.bbrc.2017.10.028
Autor:
Junken Aoki, Darlaine Pétrin, Alice Zhang, Terence E. Hébert, Dominic Devost, Rory Sleno, Asuka Inoue, Kyla Bourque, Yuji Shinjo
Publikováno v:
Journal of Biological Chemistry. 292:12139-12152
G protein-coupled receptors (GPCRs) are conformationally dynamic proteins transmitting ligand-encoded signals in multiple ways. This transmission is highly complex and achieved through induction of distinct GPCR conformations, which preferentially dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9428c97022ba176a6d3856d03540e348
https://doi.org/10.1074/jbc.m117.793877
https://doi.org/10.1074/jbc.m117.793877
Autor:
Dominic Devost, Alice Zhang, Rakan Okde, Terence E. Hébert, Junken Aoki, Yuji Shinjo, Rory Sleno, Asuka Inoue, Darlaine Pétrin
Publikováno v:
Journal of Biological Chemistry. 292:5443-5456
Here, we report the design and use of G protein-coupled receptor-based biosensors to monitor ligand-mediated conformational changes in receptors in intact cells. These biosensors use bioluminescence resonance energy transfer with Renilla luciferase (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38a6ce52d49a325282c8ff59cfe94226
https://doi.org/10.1074/jbc.m116.763854
https://doi.org/10.1074/jbc.m116.763854
Autor:
Viktoriya, Lukasheva, Dominic, Devost, Christian, Le Gouill, Yoon, Namkung, Ryan D, Martin, Jean-Michel, Longpré, Mohammad, Amraei, Yuji, Shinjo, Mireille, Hogue, Monique, Lagacé, Billy, Breton, Junken, Aoki, Jason C, Tanny, Stéphane A, Laporte, Graciela, Pineyro, Asuka, Inoue, Michel, Bouvier, Terence E, Hébert
Publikováno v:
Scientific Reports
A comprehensive understanding of signalling downstream of GPCRs requires a broad approach to capture novel signalling modalities in addition to established pathways. Here, using an array of sixteen validated BRET-based biosensors, we analyzed the abi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b69e80a3506d782860dd43799171d509
https://pubmed.ncbi.nlm.nih.gov/32471984
https://pubmed.ncbi.nlm.nih.gov/32471984
Autor:
J. Silvio Gutkind, Kouki Kawakami, Yuki Ono, Akiharu Uwamizu, Yuji Shinjo, Satoru Ishida, Nadia Arang, Robert B. Russell, Francesco Raimondi, Asuka Inoue, Takayuki Kishi, Junken Aoki, Francois Marie Ngako Kadji, Gurdeep Singh
Heterotrimetic G proteins consist of four subfamilies (G(S), G(i/O), G(q/11), and G(12/13)) that mediate signaling via G-protein-coupled receptors (GPCRs), principally by receptors binding Gα C termini. G-protein-coupling profiles govern GPCR-induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d889524007df0c70ffedf1c00c22c966
https://europepmc.org/articles/PMC6773469/
https://europepmc.org/articles/PMC6773469/
Autor:
Yuji, Shinjo, Kumiko, Makide, Keita, Satoh, Fumiya, Fukami, Asuka, Inoue, Kuniyuki, Kano, Yuko, Otani, Tomohiko, Ohwada, Junken, Aoki
Publikováno v:
Biochemical and biophysical research communications. 494(1-2)
Lysophosphatidylserine (LysoPS) has been shown to have lipid mediator-like actions to induce mast cell degranulation and suppress T lymphocyte proliferation. Recently, three G protein-coupled receptors (GPCRs), LPS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3975095605c339cafa8f714feea8594e
https://pubmed.ncbi.nlm.nih.gov/29017923
https://pubmed.ncbi.nlm.nih.gov/29017923
Autor:
Klaus Mohr, Michael Hölzel, John Sondek, Evelyn Gaffal, Thomas H. Charpentier, Graeme Milligan, Céline Galés, Tanja Slodczyk, Harald Dargatz, Tobias Bald, Junken Aoki, Yuji Shinjo, Daniel Tietze, Maike Effern, Anna Lena Schmitz, Asuka Inoue, Sylvain Armando, Henrik G. Dohlman, Anne Stößel, Ramona Schrage, Ségolène Galandrin, Gabriele M. König, Michael Hesse, Katrin M. Büllesbach, Christa E. Müller, Manuel Grundmann, Christel Drewke, Stefan Kehraus, Andrew B. Tobin, Diana Imhof, T. Kendall Harden, Suvi Annala, Stéphane A. Laporte, Jesus Gomeza, Thomas Tüting, Velten Horn, Naveen Shridhar, Nicole Merten, Yoon Namkung, Adrian J. Butcher, Daniela Wenzel, Laura Jenkins, Evi Kostenis, Michel Bouvier, Bernd K. Fleischmann, Matthew K. Martz
Publikováno v:
Nature Communications
Despite the discovery of heterotrimeric αβγ G proteins ∼25 years ago, their selective perturbation by cell-permeable inhibitors remains a fundamental challenge. Here we report that the plant-derived depsipeptide FR900359 (FR) is ideally suited t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b26f05dca16b186dc13b71425c09af5
https://eprints.gla.ac.uk/115886/1/115886.pdf
https://eprints.gla.ac.uk/115886/1/115886.pdf
Autor:
Akiharu Uwamizu, Asuka Inoue, Junken Aoki, Hiroki Kawana, Kumiko Makide, Yuji Shinjo, Kuniyuki Kano, Saki Nemoto, Kahori Namiki, Hiroshi Yukiura, Ryoji Kise, Hirotaka Matsumoto, Shizu Aikawa, Jun Ishiguro
Publikováno v:
Bioactive Lipid Mediators ISBN: 9784431556688
It is now widely accepted that lysophospholipids (LPLs), a product of the phospholipase A reaction, function as mediators through G protein-coupled receptors (GPCRs). Notably, recent studies of lysophosphatidic acid (LPA) and sphingosine 1-phosphate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57e4bd7142600d0575b97e904237fb5a
https://doi.org/10.1007/978-4-431-55669-5_8
https://doi.org/10.1007/978-4-431-55669-5_8