Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Yuji, Hoyano"'
Autor:
Yoshinobu Yamazaki, Yuji Hoyano, Itaru Maruyama, Kazuyasu Maruyama, Satoshi Tatemichi, Yoshiaki Goi, Hiroshi Kusama
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 385:845-852
We performed in vitro and in vivo experiments to evaluate the pharmacological profile of ritobegron and its effects on the bladder in rats. β3-AR selectivity was assessed using CHO cells expressing various subtypes of the human β-adrenoceptor (AR).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dda0a8b8830b681c6aa40afee2c3355
https://doi.org/10.1007/s00210-012-0755-x
https://doi.org/10.1007/s00210-012-0755-x
Autor:
Itaru Maruyama, Hiroshi Kusama, Yuji Hoyano, Kazuyasu Maruyama, Satoshi Tatemichi, Saori Yonekubo, Yoshinobu Yamazaki
Publikováno v:
Journal of Smooth Muscle Research. 48:115-124
The objective of this study was to investigate the effects of the β3-adrenoceptor (AR) agonist ritobegron on rat bladder function following partial bladder outlet obstruction and on rat salivary secretion. In addition, the effects of ritobegron were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81114e8e77f55c160bfb3713d10aec79
https://doi.org/10.1540/jsmr.48.115
https://doi.org/10.1540/jsmr.48.115
Autor:
Yoshinobu Yamazaki, Yoshitaka Tomiyama, Mamoru Kobayashi, Satoshi Tatemichi, Shinya Kobayashi, Yuji Hoyano
Publikováno v:
European Journal of Pharmacology. 613:135-140
We examined whether the effects (efficacy on the urethra and hypotension) of silodosin (alpha(1A)-adrenoceptor antagonist) and tamsulosin (alpha(1A+1D)-adrenoceptor antagonist) in dogs with benign prostatic hyperplasia altered with age. We used young
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416a8d574efd910033895f74ce5c4203
https://doi.org/10.1016/j.ejphar.2009.04.030
https://doi.org/10.1016/j.ejphar.2009.04.030
Autor:
Yasue Kubota, Yoshitaka Tomiyama, Yoshinobu Yamazaki, Hiroshi Kusama, Kenjiro Kohri, Yasunori Itoh, Yuji Hoyano, Shinya Kobayashi
Publikováno v:
World Journal of Urology. 27:775-780
This study was performed to characterize the α1-adrenoceptor subtypes in mouse ureters as regards gene expressions and contractile functions.The mRNAs for these subtypes were quantified by the real-time quantitative reverse transcription polymerase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5defb56cbf66e29dbedc6db4d9033ec0
https://doi.org/10.1007/s00345-009-0396-y
https://doi.org/10.1007/s00345-009-0396-y
Autor:
Yoshinobu Yamazaki, Hiroshi Kusama, Shinya Kobayashi, Yuji Hoyano, Kazuyasu Maruyama, Yoshitaka Tomiyama
Publikováno v:
Journal of Smooth Muscle Research. 45:187-195
To compare the efficacy of the selective alpha(1A)-adrenoceptor antagonist silodosin with those of doxazosin, terazosin, and alfuzosin against alpha-adrenoceptor agonist-induced contractions in mouse and hamster ureters.The four alpha(1)-adrenoceptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efb36e188b903da3a188271b794ca33
https://doi.org/10.1540/jsmr.45.187
https://doi.org/10.1540/jsmr.45.187
Autor:
Kiyoto Hara, Masami Kojima, Satoshi Akahane, Takashi Koizumi, Toshiki Honma, Yuji Hoyano, Masahiko Uchida, Masuo Akahane
Publikováno v:
Journal of Health Science. 49:368-378
A Cynomolgus monkey hemodialysis model was used to evaluate the efficacy of a new factor Xa (FXa) inhibitor as an anticoagulant for hemodialysis. We tested the selective FXa inhibitor KFA-1411, using doses of 0.15 mg/ kg/hr, 0.3 mg/kg/hr, and 0.6 mg/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b3f8207a364ce89a0818547b150f893
https://doi.org/10.1248/jhs.49.368
https://doi.org/10.1248/jhs.49.368
Autor:
Fumiki, Oana, Hiroshi, Onozuka, Akihiro, Tsuchioka, Takayuki, Suzuki, Nobuyuki, Tanaka, Kouichi, Kaidoh, Yuji, Hoyano, Masahiro, Hiratochi, Shinji, Kikuchi, Yasuo, Takehana, Nobuo, Shibata
Publikováno v:
The Journal of heart valve disease. 23(2)
The symptoms of Parkinson's disease are alleviated by dopamine D2 agonists, which are classified as ergot dopamine D2 agonists and non-ergot D2 agonists. Among the former, pergolide has been associated with valvular heart disease, since it has both p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8d5b3d2072c4134ba18e2e5d503ddb95
https://pubmed.ncbi.nlm.nih.gov/25076559
https://pubmed.ncbi.nlm.nih.gov/25076559
Autor:
Yoshito Nagashima, Masamichi Hirose, Yasuyuki Furukawa, Shigetoshi Chiba, Manoj Lakhe, Yuji Hoyano
Publikováno v:
Journal of Cardiovascular Pharmacology. 31:18-24
Prolongation of the functional recovery of the sinoatrial (SA) nodal pacemaker activity after overdrive, "overdrive suppression," is determined by intrinsic pacemaker activity, pacemaker site, and SA conduction. We investigated the effects of E-4031,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e47321bec9b93f2a510a84d077263d
https://doi.org/10.1097/00005344-199801000-00003
https://doi.org/10.1097/00005344-199801000-00003
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 273:H1800-H1806
To investigate the selective parasympathetic control of atrioventricular (AV) conduction during sympathetic activation, we studied the effects of cervical vagus nerve stimulation on the positive dromotropic responses to sympathetic interventions befo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3fc8715cc499ad52a07dd17fdae0853
https://doi.org/10.1152/ajpheart.1997.273.4.h1800
https://doi.org/10.1152/ajpheart.1997.273.4.h1800
Autor:
Yuji Hoyano, Yasuyuki Furukawa, Miho Kasama, Hirofumi Nakano, Shigetoshi Chiba, Hiroshi Imamura, Kyohei Yamazaki
Publikováno v:
Journal of Cardiovascular Pharmacology. 28:507-512
To investigate the role of delayed rectifier potassium current (I K ) on the sympathetic control of the heart, we studied the effects of E-403 1, a blocker of the rapidly activating type of I K (I Kr ), on the chronotropic, dromotropic, and inotropic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb623f12f65256e8bf0d80d504de5eb
https://doi.org/10.1097/00005344-199610000-00005
https://doi.org/10.1097/00005344-199610000-00005