Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Yuiko Morita-Fujimura"'
Autor:
Hideaki Tanaka, Ruhul Amin, Helen M. Cooper, Yuiko Morita-Fujimura, Yohei Shinmyo, Shuntaro Ikawa, Hirohisa Yamada, Hiroshi Tawarayama
Publikováno v:
Neuroscience. 431:184-192
The hippocampus is characterized by the presence of life-long neurogenesis. To elucidate the molecular mechanism regulating hippocampal neurogenesis, we studied the functions of the chemorepellent Draxin in neuronal proliferation and differentiation
Autor:
Sherif Rashad, Hiroyuki Sakata, Shuntaro Ikawa, Teiji Tominaga, Mika Sato-Maeda, Kuniyasu Niizuma, Yuiko Morita-Fujimura, Miki Fujimura
Publikováno v:
Journal of Stroke and Cerebrovascular Diseases. 26:1904-1911
The RING finger protein 213 (RNF213) is an important susceptibility gene for moyamoya disease (MMD) and is also implicated in other types of intracranial major artery stenosis/occlusion (ICAS); however, the role of RNF213 in the development of ICAS i
Autor:
Hideaki Tanaka, Helen M. Cooper, Masakado Kawata, Hiroshi Tawarayama, Ruhul Amin, Yohei Shinmyo, Shuntaro Ikawa, Hirohisa Yamada, Yuiko Morita-Fujimura
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Hippocampal neurogenesis in the dentate gyrus (DG) is controlled by diffusible molecules that modulate neurogenic processes, including cell proliferation, differentiation and survival. To elucidate the mechanisms underlying hippocampal neurogenesis,
Autor:
Teiji Tominaga, Hiroyuki Sakata, Atsushi Kanoke, Shigeo Kure, Kuniyasu Niizuma, Mika Sato-Maeda, Yuiko Morita-Fujimura, Akira Ito, Miki Fujimura
Publikováno v:
Brain Research. 1624:497-505
Moyamoya disease (MMD) is a chronic, occlusive cerebrovascular disease with an unknown etiology. Recent genome-wide and locus-specific association studies identified the RNF213 gene (RNF213) as an important susceptibility gene of MMD among East Asian
Autor:
Hiroyuki Sakata, Atsuo Kikuchi, Atsushi Kanoke, Yuiko Morita-Fujimura, Kuniyasu Niizuma, Shigeo Kure, Akira Ito, Miki Fujimura, Teiji Tominaga
Publikováno v:
Brain Research. 1594:310-320
Moyamoya disease (MMD) is a chronic occlusive cerebrovascular disease with unknown etiology that is characterized by the development of abnormal vascular networks at the base of the brain. Recent genome-wide studies identified RNF213 as an important
Autor:
Asuka Takehara, Tohru Kimura, Yuko Tokitake, Toru Nakano, Yuiko Morita-Fujimura, Makiko Ikeda, Yasuhisa Matsui, Yuka Obara
Publikováno v:
Development. 141:4457-4467
Primordial germ cells (PGCs) are undifferentiated germ cells in embryos, the fate of which is to become gametes; however, mouse PGCs can easily be reprogrammed into pluripotent embryonic germ cells (EGCs) in culture in the presence of particular extr
Publikováno v:
Development, Growth & Differentiation. 51:567-583
Primordial germ cells (PGCs) in mouse embryos likely include heterogeneous cells having distinct cellular properties. In the present study, we found that heterogeneity of PGCs can be defined by the expression of integrin α6 and c-Kit. The changes in
Autor:
Ronald van Marion, Winand N.M. Dinjens, Tetsuro Nishihira, Anson W. Lowe, Berna Beverloo, Chris Tselepis, Albertina W. van der Velden, Herman van Dekken, Jurjen J. Boonstra, Pierre Hainaut, Hugo W. Tilanus, Yuiko Morita-Fujimura, Yasuhisa Matsui, Erwin C.W. Beerens
Publikováno v:
Cancer Research, 67(17), 7996-8001. American Association for Cancer Research Inc.
Cancer of the esophagus is the seventh leading cause of cancer death worldwide. Esophageal carcinoma cell lines are useful models to study the biological and genetic alterations in these tumors. An important prerequisite of cell line research is the
Autor:
Kentaro Semba, Natsuko Chiba, Shuntaro Ikawa, Manabu Fukumoto, Yuiko Morita-Fujimura, Hiroshi Tawarayama, Ruhul Amin
Publikováno v:
Molecular oncology. 10(4)
Despite apparent resection of tumors, breast cancer patients often suffer relapse due to remnant dormant tumor cells. Although quiescence of cancer stem cells is thought as one of the mechanisms regulating dormancy, the mechanism underlying quiescenc
Autor:
Yuiko Morita-Fujimura, Miki Fujimura, Pak H. Chan, Anders Lewén, Michel Ferrand-Drake, Taku Sugawara, Yvan Gasche, Nobuo Noshita
Publikováno v:
The Journal of Neuroscience. 22:209-217
Mitochondria are known to be involved in the early stage of apoptosis by releasing cytochromec, caspase-9, and the second mitochondria-derived activator of caspases (Smac). We have reported that overexpression of copper/zinc superoxide dismutase (SOD