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Autor:
Yoshikazu Miura, Yuichirou Sakurai, Hiroyuki Hachiya, Tokihiko Sawada, Ken-ichi Inoue, Keiichi Kubota, Yuichi Hori, Shinzo Kimura
Publikováno v:
Toxicology. 299:165-171
Oral administration of triphenyltin chloride (TPT) (6 mg/100g body weight) inhibits insulin secretion by decreasing glucose-induced cytoplasmic Ca(2+) concentration ([Ca(2+)](i)) in pancreatic β-cells of the hamster. To test the possibility that the