Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Yuichiro Nakada"'
Autor:
Tokio Obata, Saori Deguchi, Jyoji Yoshitomi, Kazunori Inaba, Yoko Urashima, Takuro Kobori, Kouichi Hosomi, Noriaki Nagai, Yuichiro Nakada
Publikováno v:
PLoS ONE, Vol 17, Iss 11 (2022)
In this study, we focused on the storage conditions and investigated the effects of low-temperature storage (10°C) on the dispersibility of active components in three formulations of fluorometholone (FLU) suspension eye-drops (one original drug and
Externí odkaz:
https://doaj.org/article/226310dd40134f63babdd8d5385b5ab9
Autor:
Kayo Yuminoki, Fuko Seko, Shota Horii, Haruka Takeuchi, Katsuya Teramoto, Yuichiro Nakada, Naofumi Hashimoto
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 11, Iss 1, Pp 48-49 (2016)
Externí odkaz:
https://doaj.org/article/532e854552f448d6a46b57fd70e87413
Publikováno v:
Journal of Pharmaceutical Sciences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d39d7272c97c41847404392d4094d65
https://doi.org/10.1016/j.xphs.2023.03.018
https://doi.org/10.1016/j.xphs.2023.03.018
Publikováno v:
YAKUGAKU ZASSHI. 141:869-876
Quality changes associated with physical changes in suspended eye drops are difficult to predict. In this study, we attempted to evaluate the aggregation and redispersability in commercially available suspended eye drops (fluorometholone ophthalmic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226d5e0a99d452ae325ac86e88c6bc52
https://doi.org/10.1248/yakushi.21-00005
https://doi.org/10.1248/yakushi.21-00005
Publikováno v:
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 139(5)
The hydrolysis activity and expression level of carboxylesterase (CES) in skin were compared with liver and intestine in the same individual of beagle dog and cynomolgus monkey, and their aging effects were studied. CES1 isozymes were mainly present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6f842de51bd53478185a1e11701109
https://pubmed.ncbi.nlm.nih.gov/31061351
https://pubmed.ncbi.nlm.nih.gov/31061351
Publikováno v:
Journal of Pharmaceutical Sciences. 105:714-721
The expression of carboxylesterase (CES) and the transdermal movement of an ester prodrug were studied in rat skin. Ethyl-fexofenadine (ethyl-FXD) was used as a model lipophilic prodrug that is slowly hydrolyzed to its parent drug, FXD (MW 502). Amon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee45fab20181d324886c5727c4a6f393
https://doi.org/10.1002/jps.24648
https://doi.org/10.1002/jps.24648
Autor:
Shota Horii, Haruka Takeuchi, Yuichiro Nakada, Kayo Yuminoki, Katsuya Teramoto, Fuko Seko, Naofumi Hashimoto
Publikováno v:
Journal of Pharmaceutical Sciences. 103:3772-3781
In this study, we reported the application of Povacoat®, a hydrophilic polyvinylalcohol copolymer, as a dispersion stabilizer of nanoparticles of poorly water‐soluble compounds. In addition, the influence of aggregation of the nanoparticles on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4918781ac16645937cfb84315b7bca18
https://doi.org/10.1002/jps.24147
https://doi.org/10.1002/jps.24147
Autor:
Yuichiro Nakada, Shota Horii, Haruka Takeuchi, Katsuya Teramoto, Kayo Yuminoki, Fuko Seko, Naofumi Hashimoto
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 11, Iss 1, Pp 48-49 (2016)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d84b745839f2674ed0108a02a1d5615
https://doi.org/10.1016/j.ajps.2015.10.037
https://doi.org/10.1016/j.ajps.2015.10.037
Publikováno v:
International Journal of Pharmaceutics. 185:93-101
This study describes the preparation and the evaluation of biodegradable poly(L-lactide)-poly(ethylene glycol)-poly(L-lactide) copolymer (PLA-PEG-PLA) nanoparticles containing progesterone as a model drug. PLA and PLA-PEG-PLA copolymers, whose PEG co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e06b2191a1383ae558e389898cf0b9
https://doi.org/10.1016/s0378-5173(99)00153-2
https://doi.org/10.1016/s0378-5173(99)00153-2
Autor:
Reiko Tudomi, Yoshiteru Takahashi, Junko Matumoto, Kazuo Sakurai, Yuichiro Nakada, Tomomi Nakamura
Publikováno v:
Journal of Macromolecular Science, Part A. 36:1863-1877
Fractionated samples of polylactide-poly(ethylene glycol)-polylactide triblock copolymer were prepared and characterized. It was found that their molecular weights were related to the feed-ratios of monomer and initiator by the equation based on a si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27013e79efda9ef4acef1635147eee65
https://doi.org/10.1081/ma-100101630
https://doi.org/10.1081/ma-100101630