Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yuichiro Imamura"'
Autor:
Motoki Yamagishi, Yuta Ogushi, Ayana Niikura, Tomoka Ohta, Yuki Ichimura, Yu Hashimoto, Ippei Kurokawa, Hiroo Sugishita, Satoru Tanifuji, Yuichiro Imamura, Hideaki Shimoyama, Keiichiro Hayashi, Kimiyasu Ishikawa, Michiya Ohta, Haruaki Sasaki, Takashi Fukagai
Publikováno v:
International Journal of Urology. 29:566-570
Demand for erectile dysfunction treatments has increased not only in elderly patients but also in young patients. Reports indicate that frequent causes of erectile dysfunction in Japan are organic disorders in elderly patients and psychogenetic disor
Autor:
Kazuya Maeda, Yuri Tsuruya, Koji Kato, Yuji Kumagai, Hiroyuki Kusuhara, Yuichi Sugiyama, Yuichiro Imamura, Yamato Sano
Publikováno v:
Drug Metabolism and Disposition. 44:1925-1933
This study was a comprehensive analysis of metabolites in plasma and urine specimens from subjects who received probenecid, a potent inhibitor of renal organic anion transporters (OATs). Taurine and glycochenodeoxycholate sulfate (GCDCA-S) could be i
Autor:
Toshihiro Kiho, Kotaro Sugimoto, Atsushi Tengeiji, Yuichiro Imamura, Ryusuke Sugita, Harumi Kuwabara, Kohei Shimada, Kazufumi Kubota, Katsuhiro Kawakami
Publikováno v:
Inflammation. 39:907-915
Prostaglandin E2 (PGE2) is a terminal prostaglandin in the cyclooxygenase (COX) pathway. Inhibition of PGE2 production may relieve inflammatory symptoms such as fever, arthritis, and inflammatory pain. We report here the profile of a novel selective
Autor:
Yuichiro Imamura, Ryota Takahama, Etsushi Ochiai, Tetsuo Abiru, Ikuo Takahashi, Tadashi Tamura, Katsuki Takiguchi, Yorihisa Ishimaru
Publikováno v:
Journal of Structural and Construction Engineering (Transactions of AIJ). 81:281-289
Autor:
Yuichiro Imamura, Haruaki Sasaki, Motoki Yamagishi, Yoshio Ogawa, Naoya Sato, Yu Ogawa, Atsushi Koshikiya, Katsuyuki Saito, Katsuki Inoue, Makoto Shimada, Satoru Tanifuji, Jun Morita, Kohzo Fuji, Masahiro Ishihara, Yuki Matsumoto, Kenro Yamamoto, Takehiko Nakazato, Michio Naoe, Takashi Fukagai, Atsushi Igarashi, Michiya Ota, Masashi Morita, Keiichiro Hayashi, Eiji Matsubara, Hideaki Shimoyama, Yuichiro Ogawa, Takeshi Shichijyo, Kei Omori, Yuki Matsui, Kazuhiko Oshinomi
Publikováno v:
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology. 107(3)
(Objective) Enzalutamide is an oral androgen-receptor inhibitor that prolongs survival in men with castration-resistant prostate cancer (CRPC). We retrospectively evaluated clinical efficacy and safety of enzalutamide in CRPC. (Patients and methods)
Autor:
Yuri Tsuruya, Noriko Okudaira, Hiroyuki Kusuhara, Yuji Kumagai, Dominik Heer, Atsushi Kurihara, Nobuyuki Murayama, Yuichiro Imamura, Kazuya Maeda, Katja Damme, Yuichi Sugiyama, Takashi Izumi
Publikováno v:
Drug Metabolism and Disposition. 42:685-694
6β-Hydroxycortisol (6β-OHF) is a substrate of the organic anion transporter 3 (OAT3) and the multidrug and toxin extrusion proteins MATE1 and MATE-2K in the corresponding cDNA-transfected cells. This study aimed to examine the contribution of OAT3
Autor:
Takashi Izumi, Nobuyuki Murayama, Katsuhisa Inoue, Yuichiro Imamura, Hiroyuki Kusuhara, Yuichi Sugiyama, Hiroaki Yuasa, Atsushi Kurihara, Noriko Okudaira, Osamu Okazaki
Publikováno v:
Clinical Pharmacology & Therapeutics. 89:81-88
The aim of this study was to examine the mechanism underlying the elevation in serum creatinine levels caused by a novel des-fluoro(6)-quinolone antibacterial agent, DX-619, in healthy subjects. hOCT2 showed a prominent uptake of creatinine (K(m) = 5
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 328:628-634
Many fluoroquinolones are mainly eliminated by urinary excretion, in which tubular secretion by carrier-mediated transport systems has been suggested to be involved. In the present study, we examined the possibility that multidrug and toxin extrusion
Autor:
Satoru Tanifuji, Motoki Yamagishi, Kazuhiko Oshinomi, Ippei Kurokawa, Takashi Fukagai, Hideaki Shimoyama, Keiichiro Hayashi, Yuichiro Ogawa, Takeshi Shichijo, Mika Ota, K. Ishikawa, Kenro Yamamoto, Hiroo Sugishita, Yuichiro Imamura, Haruaki Sasaki
Publikováno v:
The Journal of Sexual Medicine. 14:S94-S94
Autor:
Yuichiro Imamura, Yoshinobu Takakura, Kiyoshi Yamaoka, Kazuteru Shimizu, Fumiyoshi Yamashita, Mitsuru Hashida
Publikováno v:
Biological and Pharmaceutical Bulletin. 24:930-934
The transport characteristics of a selective peripheral H1 receptor antagonist, ebastine, a substrate for cytochrome P450 3A4, and its three major metabolites, i.e., the hydroxy metabolite of ebastine (M-OH), the pharmacologically active metabolite c