Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yuichiro, Harada"'
Autor:
Sakiko Naito, Itaru Nakamura, Tomohiro Umezu, Akihiro Hata, Akira Madarame, Kumiko Uchida, Yohei Koyama, Takashi Morise, Hayato Yamaguchi, Shin Kono, Mitsushige Sugimoto, Takashi Kawai, Yuichiro Harada, Masahiko Kuroda, Masakatsu Fukuzawa, Takao Itoi
Publikováno v:
DEN Open, Vol 4, Iss 1, Pp n/a-n/a (2024)
Abstract Objectives This study aimed to prevent the infection risk of environmental contamination by feces during endoscopic procedures. We evaluated the effect of coronavirus disease 2019 (COVID‐19) on the gastrointestinal tract using fecal polyme
Externí odkaz:
https://doaj.org/article/24787b2d93294c3da8c6c33325051b1b
Autor:
Yoshiaki Yamanaka, Masahiko Kuroda, Tamami Miyagi, Kohsuke Kanekura, Satoshi Narumi, Yuichiro Harada, Yuhei Hayamizu
Publikováno v:
Biochemical and biophysical research communications. 583
Membrane-less organelles (MLOs) formed by liquid-liquid phase separation (LLPS) play pivotal roles in biological processes. During LLPS, proteins and nucleotides are extremely condensed, resulting in changes in their conformation and biological funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d57cd98c7719be1316e24912a3d9d6a8
https://pubmed.ncbi.nlm.nih.gov/34717122
https://pubmed.ncbi.nlm.nih.gov/34717122
Autor:
Yuhei Hayamizu, Satoshi Narumi, Masahiro Sugimoto, Chen Chen, Yoshiaki Yamanaka, Tamami Miyagi, Koji Ueda, Kohsuke Kanekura, Peiying Li, Yuichiro Harada, Sayaka Tezuka, Masahiko Kuroda
Publikováno v:
Journal of Cell Biology. 220
Arg (R)-rich dipeptide repeat proteins (DPRs; poly(PR): Pro-Arg and poly(GR): Gly-Arg), encoded by a hexanucleotide expansion in the C9ORF72 gene, induce neurodegeneration in amyotrophic lateral sclerosis (ALS). Although R-rich DPRs undergo liquid–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ed9dfa2a37a4df631bb111c829859a
https://doi.org/10.1083/jcb.202103160
https://doi.org/10.1083/jcb.202103160
Autor:
Yuhei Hayamizu, Tamami Miyagi, Satoshi Narumi, Yoshiaki Yamanaka, Masahiko Kuroda, Yuichiro Harada, Kohsuke Kanekura
Membrane-less organelles (MLOs) formed by liquid-liquid phase separation (LLPS) play pivotal roles in biological processes. During LLPS, proteins and nucleotides are extremely condensed, resulting in changes of their conformation and biological funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::583e67ec2378e4630dc3733d6cb6f386
https://doi.org/10.1101/2021.03.31.437991
https://doi.org/10.1101/2021.03.31.437991
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 101(10)
One of the pathological hallmarks of amyotrophic lateral sclerosis (ALS) is mislocalized, cytosolic aggregation of TAR DNA-Binding Protein-43 (TDP-43). Not only TDP-43 per se is a causative gene of ALS but also mislocalization and aggregation of TDP-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86058e1e006397939eb3ef66b24d8e45
https://pubmed.ncbi.nlm.nih.gov/34131277
https://pubmed.ncbi.nlm.nih.gov/34131277
Autor:
Chen Chen, Masahiro Sugimoto, Satoshi Narumi, Kohsuke Kanekura, Koji Ueda, Yuhei Hayamizu, Masahiko Kuroda, Peiying Li, Yuichiro Harada, Sayaka Tezuka, Yoshiaki Yamanaka
Publikováno v:
SSRN Electronic Journal.
R-rich dipeptide repeat proteins (DRPs: poly(PR) and poly(GR)), encoded by a hexanucleotide expansion in the C9ORF72 gene, induce neurodegeneration in amyotrophic lateral sclerosis (ALS). Although R-rich DRPs undergo liquid-liquid phase separation (L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaf348bcef5d01ff471fd18149c4b3f9
https://doi.org/10.2139/ssrn.3704017
https://doi.org/10.2139/ssrn.3704017
Autor:
Kentaro Nagaoka, Kohsuke Kanekura, Takuya Yagi, Yuichiro Harada, Yuhei Hayamizu, Mao Fujimoto, Masahiko Kuroda
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
Cell-penetrating peptides (CPPs) including arginine-rich peptides are attracting a lot of attention due to their potential as a novel intracellular drug delivery tool without substantial toxicity. On the other hand, disease-associated arginine-rich C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1238e9e2031ec646fdab6d1cd112e1b3
https://doi.org/10.1038/s41598-018-31096-z
https://doi.org/10.1038/s41598-018-31096-z
Autor:
Yoshihiro, Maegaki, Youichi, Kurozawa, Akiko, Tamasaki, Masami, Togawa, Akiko, Tamura, Masato, Hirao, Akihisa, Nagao, Takayuki, Kouda, Takayoshi, Okada, Hiroshi, Hayashibara, Yuichiro, Harada, Makoto, Urushibara, Chitose, Sugiura, Hitoshi, Sejima, Yuji, Tanaka, Hiroko, Matsuda-Ohtahara, Takeshi, Kasai, Kazuko, Kishi, Syunsaku, Kaji, Mitsuo, Toyoshima, Susumu, Kanzaki, Kousaku, Ohno
Publikováno v:
Brain and Development. 37:478-486
Background: Early predictors of status epilepticus (SE)-associated mortality and morbidity have not been systematically studied in children, considerably impeding the identification of patients at risk. Objectives: To determine reliable early predict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d7f7a8faa1afd2468320fb71e46624
https://doi.org/10.1016/j.braindev.2014.08.004
https://doi.org/10.1016/j.braindev.2014.08.004
Publikováno v:
Cell Fusions ISBN: 9789048197712
In fertilization, two types of sex cells or gametes – a sperm and an egg – unite in a stepwise manner to form a mother cell, which is capable of developing naturally into a new individual. Notably, the “membrane fusion” that occurs intercellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed9c100c2e0ca7307456389fcfb12c91
https://doi.org/10.1007/978-90-481-9772-9_7
https://doi.org/10.1007/978-90-481-9772-9_7
Autor:
Akiko, Kondo, Yoshiaki, Saito, Yoshihiro, Maegaki, Takehiko, Inoue, Ayumi, Seki, Yuichiro, Harada, Kousaku, Ohno
Publikováno v:
No to hattatsu = Brain and development. 38(6)
A 1-year-old girl with influenza-associated encephalopathy initially exhibited prolonged febrile convulsions and subsequent drowsiness. She became unconsciousness and experienced a cluster of seizures 4 days later. Diffusion-weighted magnetic resonan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b10498694ced587f85c2f773792b906
https://pubmed.ncbi.nlm.nih.gov/17094568
https://pubmed.ncbi.nlm.nih.gov/17094568