Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Yuichi Mitobe"'
Autor:
Toshihiko Takeiwa, Kazuhiro Ikeda, Takashi Suzuki, Wataru Sato, Kaori Iino, Yuichi Mitobe, Hidetaka Kawabata, Kuniko Horie, Satoshi Inoue
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Breast cancer is the most common cancer type among women worldwide. The majority of breast cancer expresses estrogen receptor (ER) and endocrine therapy is a standard treatment of ER-positive breast cancer. However, development of the therap
Externí odkaz:
https://doaj.org/article/d7b12b2ff1b34ba4925abba8cf603547
Autor:
Kuniko Horie, Kiyoshi Takagi, Toshihiko Takeiwa, Yuichi Mitobe, Hidetaka Kawabata, Takashi Suzuki, Kazuhiro Ikeda, Satoshi Inoue
Publikováno v:
Cells, Vol 11, Iss 22, p 3610 (2022)
Recent advances in RNA studies have revealed that functional long noncoding RNAs (lncRNAs) contribute to the biology of cancers. In breast cancer, estrogen receptor α (ERα) is an essential transcription factor that primarily promotes the growth of
Externí odkaz:
https://doaj.org/article/c2944ec506f94e25afca0090caeabc05
Autor:
Tadasuke Naito, Jun-ichirou Yasunaga, Yuichi Mitobe, Kazumasa Shirai, Hiroe Sejima, Hiroshi Ushirogawa, Yuetsu Tanaka, Tatsufumi Nakamura, Kousuke Hanada, Masahiro Fujii, Masao Matsuoka, Mineki Saito
Publikováno v:
Retrovirology, Vol 15, Iss 1, Pp 1-20 (2018)
Abstract Background Among human T cell leukemia virus type 1 (HTLV-1)-infected individuals, there is an association between HTLV-1 tax subgroups (subgroup-A or subgroup-B) and the risk of HAM/TSP in the Japanese population. To investigate the role of
Externí odkaz:
https://doaj.org/article/a8b4dee0cf52421caf3f32977380ee39
Autor:
Toshihiko Takeiwa, Yuichi Mitobe, Kazuhiro Ikeda, Kosei Hasegawa, Kuniko Horie, Satoshi Inoue
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 11242 (2021)
Patients with advanced ovarian cancer usually exhibit high mortality rates, thus more efficient therapeutic strategies are expected to be developed. Recent transcriptomic studies revealed that long intergenic noncoding RNAs (lincRNAs) can be a new cl
Externí odkaz:
https://doaj.org/article/fae42aef3de5445d91ff1c2ccf09f597
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1551 (2020)
Splicing of mRNA precursor (pre-mRNA) is a mechanism to generate multiple mRNA isoforms from a single pre-mRNA, and it plays an essential role in a variety of biological phenomena and diseases such as cancers. Previous studies have demonstrated that
Externí odkaz:
https://doaj.org/article/43f48dc855d9441facee835831ec6358
Autor:
Keiko Yasuma, Jun-ichirou Yasunaga, Keiko Takemoto, Kenji Sugata, Yuichi Mitobe, Norihiro Takenouchi, Masanori Nakagawa, Yutaka Suzuki, Masao Matsuoka
Publikováno v:
PLoS Pathogens, Vol 12, Iss 1, p e1005372 (2016)
Human T-cell leukemia virus type 1 (HTLV-1) infects CD4+ T cells and induces proliferation of infected cells in vivo, which leads to the onset of adult T-cell leukemia (ATL) in some infected individuals. The HTLV-1 bZIP factor (HBZ) gene, which is en
Externí odkaz:
https://doaj.org/article/06cfcda880b5406596fc909ef3eab1e4
Autor:
Satoshi Inoue, Kuniko Horie-Inoue, Yutaka Suzuki, Hidetaka Kawabata, Kenjiro Aogi, Takashi Suzuki, Kazuhiro Ikeda, Ken-ichi Takayama, Kaori Iino, Yuichi Mitobe
This file contains Supplementary Figure S1. High PSF expression is positively associated with poor prognosis of breast cancer patients.; Supplementary Figure S2. ESR1 expression is elevated in endocrine resistance model hydroxytamoxifen-resistant OHT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f89886443147a525e19c882f196d2a2
https://doi.org/10.1158/0008-5472.22423803
https://doi.org/10.1158/0008-5472.22423803
Autor:
Masao Matsuoka, Koichi Ohshima, Kazutaka Nakashima, Chiho Onishi, Mohamed Mahgoub, Rie Furuta, Yuichi Mitobe, Haruka Kinosada, Jun-ichirou Yasunaga, Kenji Sugata
CD103 expression in ATL patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb6a8e491ea6d78337a14f9ab531aaca
https://doi.org/10.1158/0008-5472.22413972.v1
https://doi.org/10.1158/0008-5472.22413972.v1
Autor:
Masao Matsuoka, Koichi Ohshima, Kazutaka Nakashima, Chiho Onishi, Mohamed Mahgoub, Rie Furuta, Yuichi Mitobe, Haruka Kinosada, Jun-ichirou Yasunaga, Kenji Sugata
Quantitative analyses of usHBZ and sHBZ transcripts in PBMCs of ATL patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::280c5776c092166550a47cde8ff1d422
https://doi.org/10.1158/0008-5472.22413981
https://doi.org/10.1158/0008-5472.22413981
Autor:
Satoshi Inoue, Kuniko Horie-Inoue, Yutaka Suzuki, Hidetaka Kawabata, Kenjiro Aogi, Takashi Suzuki, Kazuhiro Ikeda, Ken-ichi Takayama, Kaori Iino, Yuichi Mitobe
Endocrine therapy is standard treatment for estrogen receptor (ER)-positive breast cancer, yet long-term treatment often causes acquired resistance, which results in recurrence and metastasis. Recent studies have revealed that RNA-binding proteins (R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c0012ae681667c1817472a110dd284f
https://doi.org/10.1158/0008-5472.c.6511587.v1
https://doi.org/10.1158/0008-5472.c.6511587.v1