Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Yuichi Mazaki"'
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Neutrophils depend heavily on glycolysis for energy production under normal conditions. In contrast, neutrophils require energy supplied by mitochondrial oxidative phosphorylation (OXPHOS) during chemotaxis. However, the mechanism
Externí odkaz:
https://doaj.org/article/58a953e3095749dcbb88cc5c25bc5c89
Publikováno v:
Journal of Pharmacological Sciences, Vol 143, Iss 4, Pp 315-319 (2020)
This study examined the possible involvement of Ca2+-sensing receptor (CaSR) in nitric oxide (NO) production in human vascular endothelial cells. Extracellular Ca2+ elevated the intracellular Ca2+ concentration, the endothelial NO synthase (eNOS) pho
Externí odkaz:
https://doaj.org/article/dd439fb43f8a41a585cdc5451c48664e
Publikováno v:
Journal of Pharmacological Sciences, Vol 140, Iss 1, Pp 102-105 (2019)
Endothelin type A receptor (ETAR) is internalized upon agonist stimulation; however, the mechanism thereof remains controversial. In this study, we characterized the endothelin-1 (ET-1)-induced internalization of ETAR expressed in Chinese hamster ova
Externí odkaz:
https://doaj.org/article/dc82a7f6cfce4b46a710db4759700353
Autor:
Kazuki Sato, Hiroshi Ohira, Takahiro Horinouchi, Toshitaka Nakaya, Yuichi Mazaki, Ayako Sugimoto, Taku Watanabe, Ichizo Tsujino, Masaharu Nishimura
Publikováno v:
Respiratory Medicine Case Reports, Vol 26, Iss , Pp 265-269 (2019)
A recent case report described a case of pulmonary arterial hypertension (PAH) associated with use of the Chinese herbal medicine Qing-Dai; however, the clinical course and possible mechanisms have not been characterized. We present the case of a man
Externí odkaz:
https://doaj.org/article/7705bc9b74604d21b949be0940ff60e5
Autor:
Yuichi Mazaki, Yasuhito Onodera, Tsunehito Higashi, Takahiro Horinouchi, Tsukasa Oikawa, Hisataka Sabe
Publikováno v:
Cell Communication and Signaling, Vol 15, Iss 1, Pp 1-10 (2017)
Abstract Background The small GTPase ARF1 mediates membrane trafficking mostly from the Golgi, and is essential for the G protein-coupled receptor (GPCR)-mediated chemotaxis of neutrophils. In this process, ARF1 is activated by the guanine nucleotide
Externí odkaz:
https://doaj.org/article/d63fb7f8a8a2413fb303a405597c31e2
Autor:
Aya Nawata, Hirotsugu Noguchi, Yuichi Mazaki, Toshihiro Kurahashi, Hiroto Izumi, Ke-Yong Wang, Xin Guo, Hidetaka Uramoto, Kimitoshi Kohno, Hatsumi Taniguchi, Yoshiya Tanaka, Junichi Fujii, Yasuyuki Sasaguri, Akihide Tanimoto, Toshiyuki Nakayama, Sohsuke Yamada
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152549 (2016)
BACKGROUND:Accumulating evidence has shown that methionine- and choline-deficient high fat (MCD+HF) diet induces the development of nonalcoholic fatty liver disease (NAFLD), in which elevated reactive oxygen species play a crucial role. We have repor
Externí odkaz:
https://doaj.org/article/b352f5b7fe644fcaa0f3a987744c42ae
Publikováno v:
Biological and Pharmaceutical Bulletin. 43:1804-1809
Acrolein (ACR), a highly reactive α,β-unsaturated aldehyde, is a major cytotoxic factor in nicotine- and tar-free cigarette smoke extract (CSE). There are conflicting results regarding endothelial functions despite the fact that both CSE and ACR ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bbfce11dafd8d0229e525d67a3c6825
https://doi.org/10.1248/bpb.b20-00522
https://doi.org/10.1248/bpb.b20-00522
Publikováno v:
Journal of Pharmacological Sciences, Vol 143, Iss 4, Pp 315-319 (2020)
This study examined the possible involvement of Ca2+-sensing receptor (CaSR) in nitric oxide (NO) production in human vascular endothelial cells. Extracellular Ca2+ elevated the intracellular Ca2+ concentration, the endothelial NO synthase (eNOS) pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876e8f649cae2775fd531d4ea44c5939
https://doi.org/10.1016/j.jphs.2019.06.009
https://doi.org/10.1016/j.jphs.2019.06.009
Autor:
Tsunehito Higashi, Hisataka Sabe, Yuichi Mazaki, Shingo Takada, Yasuhito Onodera, Junko Nio-Kobayashi, Satoshi Maekawa
Publikováno v:
Biochemical and Biophysical Research Communications. 513:708-713
Neutrophils rapidly migrate to infection sites after the recognition of invaders. During chemotaxis, neutrophils require energy supplied by mitochondria oxidative phosphorylation (OXPHOS), whereas neutrophils rely heavily on glycolysis under normal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef9ae13d2e0c0860946a0aa92b4ff5c
https://doi.org/10.1016/j.bbrc.2019.04.037
https://doi.org/10.1016/j.bbrc.2019.04.037
Publikováno v:
Journal of Pharmacological Sciences, Vol 140, Iss 1, Pp 102-105 (2019)
Endothelin type A receptor (ETAR) is internalized upon agonist stimulation; however, the mechanism thereof remains controversial. In this study, we characterized the endothelin-1 (ET-1)-induced internalization of ETAR expressed in Chinese hamster ova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace259c13e58b86e57e01c3c7a7a2127
https://doi.org/10.1016/j.jphs.2019.03.008
https://doi.org/10.1016/j.jphs.2019.03.008