Zobrazeno 1 - 10
of 272
pro vyhledávání: '"Yuichi Kumahara"'
Autor:
Takero Sugiura, Kohzoh Imai, Yuichi Kumahara, Isao Hayashi, Tokuo Nakajima, Akiyoshi Kajita, Yoshikatsu Tabuchi, Masayuki Tsujisaki, Tsukasa Noguchi, Motoaki Dodo
Publikováno v:
Internal Medicine. 37:123-126
We investigated the effects of risk factors of atherosclerosis on soluble intercellular adhesion molecule-1 (sICAM-1) concentration and leukocyte count by using multivariate statistical analysis. The subjects were 90 people who were hospitalized for
Publikováno v:
Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. 34:359-388
Glucose tolerance is reported to be impaired in the elderly, and this is said to be mainly due to a decrease in insulin sensitivity (insulin resistance). Insulin resistance is known to be associated with atherosclerosis and coronary artery disease. T
Autor:
Kouzin Kamino, Yukiko Nakata, Yoshikatsu Tabuchi, Seiju Takami, Mitsuru Ohishi, Tomohiro Katsuya, Hiromi Rakugi, Yuichi Kumahara, Jitsuo Higaki, Toshio Ogihara, Tetsuro Miki
Publikováno v:
Hypertension. 27:1205-1209
Abstract The apolipoprotein ε4 allele and homozygous deletion allele ( DD ) of the angiotensin-converting enzyme gene are reported to be associated with an increase in the incidence of ischemic heart disease. In this study, we examined whether the a
Autor:
Y. Hamada, Hironori Ueda, Yusuke Nakagawa, Eiji Yamato, Toshio Ogihara, Yuichi Kumahara, K. Takekawa, Tomomi Fujisawa, Yasuko Uchigata, Hiroshi Ikegami, Takafumi Miki
Publikováno v:
Biochemical and Biophysical Research Communications. 209:664-668
Mitochondria play an important role in glucose-induced insulin secretion in pancreatic beta cells. We therefore examined whether patients with NIDDM exhibit genetic variability in mitochondrial DNA (mtDNA), a candidate gene for NIDDM. We sequenced mt
Autor:
Ken Ichiro Fukuchi, Kiyoji Tanaka, Tetsuro Miki, Kouzin Kamino, Jun Nakura, Yuji Takemoto, Toshio Ogihara, Yuichi Kumahara
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 29:195-198
Autor:
Yoshihiko Fujioka, Yuichi Kumahara, Tetsuro Miki, Hironori Ueda, Masahiro Fukuda, Kiyoshi Takegawa, Toshio Ogihara, Yoshihiko Kawaguchi, Hiroshi Ikegami, Tomomi Fujisawa
Publikováno v:
Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. 30:622-625
Recently, high frequencies of glucose intolerance and insulin resistance have been reported in patients with hypertension. However, both blood pressure and glucose tolerance are influenced by age. To investigate the effect of age on the interaction b
Autor:
Ikuo Yamamori, Yuichi Kumahara, Tsukasa Noguchi, Tokuo Nakajima, Junta Takamatsu, Yuichi Mori
Publikováno v:
Internal Medicine. 32:6-9
Complete thyroxine-binding globulin deficiency (TBG-CD) was uncovered in a subject receiving a comprehensive health examination. The subject had an abnormally high T3 resin uptake. A family study showed that the TBG abnormality had been inherited by
Autor:
Kikuo Arakawa, Teruo Omae, Masao Ikeda, Kaoru Yoshinaga, Yuichi Kumahara, Tatsuo Kokubu, Toshio Ogihara, Kazuo Yamada, Masao Ishii, Yoshihiro Kaneko
Publikováno v:
American Journal of Hypertension. 4:42S-45S
Delapril, a new angiotensin converting enzyme (ACE) inhibitor discovered in the laboratory of Takeda Chemical Industries, Ltd., is the result of drug design based on the structure-activity relationships of ACE inhibitors. Delapril is an antihypertens
Autor:
Jitsuo Higaki, Yukiko Nakata, Atsunori Okamura, Yoshihiro Yanagitani, Toshio Ogihara, Seiju Takami, Mitsuru Ohishi, Tomohiro Katsuya, Yuichi Kumahara, Hiromi Rakugi, Tetsuro Miki, Yoshikatsu Tabuchi, Hiroshi Ikegami, Kei Kamide
Publikováno v:
Clinical and experimental pharmacologyphysiology. 27(7)
SUMMARY 1. Deletion polymorphism, DD, of the angiotensin-converting enzyme (ACE) gene is reported to be related to cardiovascular disease, which is frequently based on insulin resistance. 2. To clarify the relationship between the ACE genotype DD and