Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Yuichi, Wakana"'
Autor:
Pablo Lujan, Carla Garcia-Cabau, Yuichi Wakana, Javier Vera Lillo, Carmen Rodilla-Ramírez, Hideaki Sugiura, Vivek Malhotra, Xavier Salvatella, Maria F Garcia-Parajo, Felix Campelo
Publikováno v:
eLife, Vol 12 (2024)
Secretory proteins are sorted at the trans-Golgi network (TGN) for export into specific transport carriers. However, the molecular players involved in this fundamental process remain largely elusive. Here, we identified the human transmembrane protei
Externí odkaz:
https://doaj.org/article/6941725be9904fe88ea7ca8d85a07ae9
Autor:
Yuichi Wakana, Felix Campelo
Publikováno v:
Cells, Vol 10, Iss 7, p 1618 (2021)
Membrane trafficking is essential for processing and transport of proteins and lipids and to establish cell compartmentation and tissue organization. Cells respond to their needs and control the quantity and quality of protein secretion accordingly.
Externí odkaz:
https://doaj.org/article/e16feeb033244193a825a340df74f16b
Legionella effector Lpg1137 shuts down ER-mitochondria communication through cleavage of syntaxin 17
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
The pathogenic bacteriumLegionella pneumophila replicates within macrophages. Here, the authors show that L. pneumophilasecretes an effector protein that cleaves the host protein syntaxin 17, thus inhibiting autophagy and staurosporine-induced apopto
Externí odkaz:
https://doaj.org/article/ec754c6774e2435dac51a43ad70686a2
Autor:
Yuichi, Wakana, Mitsuo, Tagaya
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2557
Sorting and transport of secretory and membrane proteins occur at the trans-Golgi network (TGN). Carriers of the TGN to the cell surface (CARTS) are one of the carriers that mediate the transport of certain proteins from the TGN to the plasma membran
Autor:
Pablo Lujan, Carla Garcia-Cabau, Yuichi Wakana, Carmen Rodilla-Ramírez, Vivek Malhotra, Xavier Salvatella, Maria F. Garcia-Parajo, Felix Campelo
Secretory proteins are sorted at the trans-Golgi network (TGN) for export into specific transport carriers. However, the molecular players involved in this fundamental process remain largely elusive. Here, we identified the transmembrane protein TGN4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96519b64bda79e476ac67f2b0cb071cc
https://doi.org/10.1101/2022.04.20.488883
https://doi.org/10.1101/2022.04.20.488883
Autor:
Hiroki Inoue, Kaito Hayashi, Mitsuo Tagaya, Jessica Angulo-Capel, Hidetoshi Kumata, Yuichi Wakana, Masato Taoka, Felix Campelo, Tomonari Umemura, Takumi Nemoto, Chiaki Watanabe, Kohei Arasaki, Maria F. Garcia-Parajo
Publikováno v:
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
The Journal of Cell Biology
Universitat Politècnica de Catalunya (UPC)
The Journal of Cell Biology
Wakana et al. describe a new role for SCAP, a key regulatory protein in cholesterol metabolism, in promoting Golgi PI4P turnover and the biogenesis of the TGN-derived transport carriers CARTS via interaction with the cholesterol/PI4P exchange machine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf3e1139e167ce454cd94e386159f5b
Autor:
Shun Kato, Kohei Arasaki, Natsuki Tokutomi, Yuzuru Imai, Tsuyoshi Inoshita, Nobutaka Hattori, Taeko Sasaki, Miyuki Sato, Yuichi Wakana, Hiroki Inoue, Mitsuo Tagaya
Publikováno v:
Journal of Cell Science; Nov2021, Vol. 134 Issue 22, p1-12, 12p
Autor:
Hidetoshi Kumata, Mitsuo Tagaya, Felix Campelo, Hiroki Inoue, Yuichi Wakana, Masato Taoka, Tomonari Umemura, Chiaki Watanabe, Kohei Arasaki, Takumi Nemoto, Kaito Hayashi
In response to cholesterol deprivation, SCAP escorts SREBP transcription factors from the endoplasmic reticulum (ER) to the Golgi complex for their proteolytic activation, leading to gene expression for cholesterol synthesis and uptake. Here we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91864db4376feb95cce9511596196ec8
Autor:
Mitsuo Tagaya, Nanako Oyama, Motohide Murate, Hiroki Inoue, Kohei Arasaki, Yuichi Wakana, Toshihide Kobayashi, Richika Kotake
Publikováno v:
Molecular Biology of the Cell
Biogenesis of the TGN-derived transport carriers CARTS requires the ER protein VAP and Golgi lipid transfer proteins, ceramide transfer protein and OSBP. Sac1 lipid phosphatase is recruited to a VAP–OSBP complex formed at an ER subdomain closely ap
Autor:
Yoko Aoki, Kana Hasegawa, Hideki Yamaguchi, Yuichi Wakana, Hiroki Inoue, Kenichi Asano, Takuya Watanabe, Yuka Otagiri, Masato Tanaka, Mitsuo Tagaya, Kohei Arasaki, Takuya Miyagawa
Publikováno v:
The Journal of Cell Biology
Invasive cancer cells degrade and invade into the extracellular matrix by expressing the matrix metalloproteinase MT1-MMP at invadopodia. Miyagawa et al. show that MT1-MMP uses the ER-Golgi SNARE Bet1 to facilitate its own transport to the plasma mem