Výsledky vyhledávání - "Yuichi, Tokito"

Human T-cell lymphotropic virus type I Tax activates lung resistance-related protein expression in leukemic clones established from an adult T-cell leukemia patient

Autor: Megumi Umehara, Yuichi Tokito, Yoshimune Sakaki, Takeshi Yoshiyama, Chuwa Tei, Hideo Ohtsubo, Akihiko Yamaguchi, Naomichi Arima, Kosei Arimura, Nakaaki Kawamata, Kenji Terashi, Hiroyasu Mori

Publikováno v: Experimental Hematology. 30:340-345

Objective We examined the significance of human T-cell lymphotropic virus type I (HTLV-I) Tax protein-induced resistance to anticancer drugs and the relationship between Tax and multidrug resistance proteins. Materials and Methods. S1T cell, a leukem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d40c411ece21c0bd546922ffa6475e19
https://doi.org/10.1016/s0301-472x(02)00775-0

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Granulocyte colony-stimulating factor production by adult T-cell leukaemia cells

Autor: Hideo Ohtsubo, Kosei Arimura, Hiroshi Fujiwara, Katsuya Yamaguchi, Shiroh Hidaka, Toshimasa Kukita, Tadashi Matsumoto, Atsuo Ozaki, Yuichi Tokito, Kakushi Matsushita, Naomichi Arima, Chuwa Tei

Publikováno v: British Journal of Haematology. 111:208-215

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::78769fbcd8dbf197cc8a0ade6d2ffbd8
https://doi.org/10.1111/j.1365-2141.2000.02257.x

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Antiproliferative effects of gefitinib are associated with suppression of E2F-1 expression and telomerase activity

Autor: Mitsuhiro, Suenaga, Akihiko, Yamaguchi, Hiroshi, Soda, Koji, Orihara, Yuichi, Tokito, Yoshimune, Sakaki, Megumi, Umehara, Kenji, Terashi, Nakaaki, Kawamata, Mikio, Oka, Shigeru, Kohno, Chuwa, Tei

Publikováno v: Anticancer research. 26(5A)

Gefitinib (Iressa, ZD1839) is a selective epidermal growth factor receptor tyrosine kinase inhibitor. E2F-1 is a critical determinant in cell cycle. Growth signals up-regulate telomerase activity. The effects of gefitinib on E2F-1 and telomerase in A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e44b54b407c22a04e420341cad704e2e
https://pubmed.ncbi.nlm.nih.gov/17094457

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HTLV-I Tax protein inhibits apoptosis induction but not G1 arrest by pyrrolidinedithiocarbamate, an anti-oxidant, in adult T cell leukemia cells

Autor: Kosei Arimura, Toshimasa Kukita, Hciichiro Hamada, Yoshimune Sakaki, Yuichi Tokito, Koji Orihara, Atsuo Ozaki, Takafumi Hagiwara, Chuwa Tei, Kakushi Matsushita, Naomichi Arima, Masaki Akimoto

Publikováno v: Experimental hematology. 32(2)

Objective We examined the anti-tumor effect of pyrrolidinedithiocarbamate (PDTC) on HTLV-1-infected T clones and the mechanism of HTLV-1 Tax protein inhibition of PDTC-induced apoptosis. Materials and Methods Tax-nonproducing clones S1T and Su9T01, T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf49f2f7ffbab8e80d5a2d30b1953e3
https://pubmed.ncbi.nlm.nih.gov/15102481

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Granulocyte colony-stimulating factor production by adult T-cell leukaemia cells

Autor: Chuwa Tei, Toshimasa Kukita, Hiroshi Fujiwara, Tadashi Matsumoto, Shiroh Hidaka, Yuichi Tokito, Atsuo Ozaki, Hideo Ohtsubo, Katsuya Yamaguchi, Kakushi Matsushita, Kosei Arimura, Naomichi Arima

Publikováno v: British journal of haematology. 111(1)

We previously demonstrated that, in about 30% of primary adult T-cell leukaemia (ATL) cases, the leukaemic cells proliferated in response to granulocyte colony-stimulating factor (G-CSF). In the present report, we describe five patients with the acut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd54e546ab3b544cb68e31c72313a08
https://pubmed.ncbi.nlm.nih.gov/11091203

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