Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yuhui Ou"'
Publikováno v:
eLife, Vol 6 (2017)
Metformin, a widely used first-line drug for treatment of type 2 diabetes (T2D), has been shown to extend lifespan and delay the onset of age-related diseases. However, its primary locus of action remains unclear. Using a pure in vitro reconstitution
Externí odkaz:
https://doaj.org/article/14cddf124ac142278443a0398cc40e11
Autor:
Jialiang Guan, Jie Chen, Dong Wang, Peixue Xia, Yi Li, Yuhui Ou, Ying Liu, Jie Wang, Rong Luo, Peng Chen
Publikováno v:
Nature. 596:281-284
The mTOR complex 1 (mTORC1) controls cell growth in response to amino acid levels1. Here we report SAR1B as a leucine sensor that regulates mTORC1 signalling in response to intracellular levels of leucine. Under conditions of leucine deficiency, SAR1
Autor:
Yuhui Ouyang, Jun Yang, Jingxuan Zhang, Yun Yan, Shengzhi Sun, Jiajia Wang, Xiaobo Li, Rui Chen, Luo Zhang
Publikováno v:
Clinical and Translational Allergy, Vol 14, Iss 7, Pp n/a-n/a (2024)
Abstract Background Airborne pollen is a crucial risk factor in allergic rhinitis (AR). The severity of AR symptoms can vary based on pollen type and concentration. This study aimed to estimate the association between exposure to different pollen typ
Externí odkaz:
https://doaj.org/article/637a06b548094a49a078abb57a4eb71e
Autor:
Xiping Li, Jiawen He, Zhonglue Hu, Xin Ye, Sisi Wang, Yuan Zhao, Bin Wang, Yuhui Ou, Jiazhen Zhang
Publikováno v:
Composites Science and Technology. 229:109707
Autor:
Dong Wang, Chenchen Xu, Wenyu Yang, Jie Chen, Yuhui Ou, Yuanyuan Guan, Jialiang Guan, Ying Liu
Publikováno v:
Molecular cell. 82(4)
The mTOR complex 1 (mTORC1) is an essential metabolic hub that coordinates cellular metabolism with the availability of nutrients, including amino acids. Sestrin2 has been identified as a cytosolic leucine sensor that transmits leucine status signals
Autor:
Huai-Bin Li, Feng Wu, Chenyang Ling, Huachun Miao, Yuhui Ou, Longchi Chen, Peng Ji, Quan Yuan, Ao Cao
Background: Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease. Its pathogenesis is complex and consists of different types of heart malformations. Whether for diagnosis or treatment, it is necessary to understand, in dept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24658567e6259b0ca3ad34b919c42a11
https://doi.org/10.21203/rs.3.rs-331671/v1
https://doi.org/10.21203/rs.3.rs-331671/v1
Publikováno v:
Nature. 557(7706)
The mechanistic target of rapamycin complex 1 (mTORC1) is a master regulator of cell growth that responds to a diverse set of environmental cues, including amino acids1,2. Deregulation of mTORC1 has been linked with metabolic diseases, cancer and age
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
Metformin, a widely used first-line drug for treatment of type 2 diabetes (T2D), has been shown to extend lifespan and delay the onset of age-related diseases. However, its primary locus of action remains unclear. Using a pure in vitro reconstitution
Publikováno v:
Clinical and Translational Allergy, Vol 13, Iss 7, Pp n/a-n/a (2023)
Abstract Background Artemisia pollen is the most prevalent outdoor aeroallergen causing respiratory allergies in Beijing, China. Pollen allergen concentrations have a direct impact on the quality of life of those suffering from allergies. Artemisia p
Externí odkaz:
https://doaj.org/article/d1ff4abb65944d56a73bbe510af97212
Publikováno v:
World Allergy Organization Journal, Vol 16, Iss 4, Pp 100762- (2023)
The prevalence of allergic rhinitis (AR) caused by pollen allergen is high in northern China. This study analyzed the allergen detection results of patients with AR in Beijing Tongren Hospital from 2016 to 2019, and evaluated the association between
Externí odkaz:
https://doaj.org/article/55cc910c3c574b408a27e6dea5821c67