Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Yuhsuke Ohmi"'
Autor:
Hiromi Miura, Ayaka Nakamura, Aki Kurosaki, Ai Kotani, Masaru Motojima, Keiko Tanaka, Shigeru Kakuta, Sanae Ogiwara, Yuhsuke Ohmi, Hirotaka Komaba, Samantha L.P. Schilit, Cynthia C. Morton, Channabasavaiah B. Gurumurthy, Masato Ohtsuka
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Transgenic (Tg) mice are widely used in biomedical research, and they are typically generated by injecting transgenic DNA cassettes into pronuclei of one-cell stage zygotes. Such animals often show unreliable expression of the tra
Externí odkaz:
https://doaj.org/article/9cef2d51b1ca43d99f22dfc17cc3a973
Publikováno v:
FEBS Open Bio, Vol 13, Iss 9, Pp 1615-1624 (2023)
Genetic disruption of glycosyltransferases has provided clear information on the roles of their reaction products in the body. Our group has studied the function of glycosphingolipids by genetic engineering of glycosyltransferases in cell culture and
Externí odkaz:
https://doaj.org/article/8cc4fd0b374948029e81dc2c818439ee
Autor:
Farhana Yesmin, Keiko Furukawa, Mariko Kambe, Yuhsuke Ohmi, Robiul Hasan Bhuiyan, Mohammad Abul Hasnat, Momoka Mizutani, Orie Tajima, Noboru Hashimoto, Akiko Tsuchida, Kei Kaneko, Koichi Furukawa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Exosomes (small extracellular vesicles: EVs) have attracted increasing attention from basic scientists and clinicians since they play important roles in cell-to-cell communication in various biological processes. Various features of EVs have
Externí odkaz:
https://doaj.org/article/7702f35ab2754bb48b2a1bc84df9e75d
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281414 (2023)
Gangliosides, sialic acid-containing glycosphingolipids, are widely involved in regulations of signal transductions to control cellular functions. It has been suggested that GM3, the simplest structure among gangliosides, is involved in insulin resis
Externí odkaz:
https://doaj.org/article/b1ca69ebd0d6472bb6e3abc292f51d93
Autor:
Farhana Yesmin, Robiul H. Bhuiyan, Yuhsuke Ohmi, Satoko Yamamoto, Kei Kaneko, Yuki Ohkawa, Pu Zhang, Kazunori Hamamura, Nai-Kong V. Cheung, Norihiro Kotani, Koichi Honke, Tetsuya Okajima, Mariko Kambe, Orie Tajima, Keiko Furukawa, Koichi Furukawa
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 423 (2021)
Gangliosides have been considered to modulate cell signals in the microdomain of the cell membrane, lipid/rafts, or glycolipid-enriched microdomain/rafts (GEM/rafts). In particular, cancer-associated gangliosides were reported to enhance the malignan
Externí odkaz:
https://doaj.org/article/f92713136d7645d19bbbbc5a547f8d7f
Autor:
Songhai Tian, Khaja Muneeruddin, Mei Yuk Choi, Liang Tao, Robiul H Bhuiyan, Yuhsuke Ohmi, Keiko Furukawa, Koichi Furukawa, Sebastian Boland, Scott A Shaffer, Rosalyn M Adam, Min Dong
Publikováno v:
PLoS Biology, Vol 16, Iss 11, p e2006951 (2018)
Glycosylation is a fundamental modification of proteins and membrane lipids. Toxins that utilize glycans as their receptors have served as powerful tools to identify key players in glycosylation processes. Here, we carried out Clustered Regularly Int
Externí odkaz:
https://doaj.org/article/0f48c87560b048dfb243742369a2031a
Autor:
Yuhsuke Ohmi, Wataru Ise, Akira Harazono, Daisuke Takakura, Hidehiro Fukuyama, Yoshihiro Baba, Masashi Narazaki, Hirofumi Shoda, Nobunori Takahashi, Yuki Ohkawa, Shuting Ji, Fumihiro Sugiyama, Keishi Fujio, Atsushi Kumanogoh, Kazuhiko Yamamoto, Nana Kawasaki, Tomohiro Kurosaki, Yoshimasa Takahashi, Koichi Furukawa
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Post-translational modifications, such as glycosylation and sialylation, are thought to confer disease modifying effects on autoimmune-associated antibodies, including anti-citrullinated protein antibodies in rheumatoid arthritis. Here the authors sh
Externí odkaz:
https://doaj.org/article/626de5323ebb454892d4e77327d0fdec
Autor:
Koichi Furukawa, Yuhsuke Ohmi, Farhana Yesmin, Orie Tajima, Yuji Kondo, Pu Zhang, Noboru Hashimoto, Yuki Ohkawa, Robiul H. Bhuiyan, Keiko Furukawa
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 1906 (2020)
Acidic glycosphingolipids, i.e., gangliosides, are predominantly and consistently expressed in nervous tissues of vertebrates at high levels. Therefore, they are considered to be involved in the development and function of nervous systems. Recent stu
Externí odkaz:
https://doaj.org/article/ffa658164bed40c68f930ecdd01441ca
Autor:
Yuhsuke Ohmi, Mariko Kambe, Yuki Ohkawa, Kazunori Hamamura, Orie Tajima, Rika Takeuchi, Koichi Furukawa, Keiko Furukawa
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206881 (2018)
Ganglioside GD3 is widely expressed in human malignant melanomas, and has been reported to be involved in the increased cell proliferation and invasion. In this study, we established GM3-, GM2-, GM1-, GD3-, or GD2-expressing melanoma cell lines by tr
Externí odkaz:
https://doaj.org/article/ccb531e332ca49d78e02bbb4138093cb
Autor:
Hasnat, Mohammad Abul, Yuhsuke Ohmi, Farhana Yesmin, Mariko Kambe, Yoshiyuki Kawamoto, Bhuiyan, Robiul H., Momoka Mizutani, Noboru Hashimoto, Akiko Tsuchida, Yuki Ohkawa, Kei Kaneko, Orie Tajima, Keiko Furukawa, Koichi Furukawa
Publikováno v:
Nagoya Journal of Medical Science; Aug2024, Vol. 86 Issue 3, p435-451, 17p