Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Yuho Kim"'
Autor:
Prasanna Katti, Alexander S. Hall, Hailey A. Parry, Peter T. Ajayi, Yuho Kim, T. Bradley Willingham, Christopher K. E. Bleck, Han Wen, Brian Glancy
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
How different physical configurations between sarcomeres and mitochondria alter energetic support for contractile function of skeletal muscle is not clear. Here the authors use advanced 3D imaging and analysis techniques to show how space is made for
Externí odkaz:
https://doaj.org/article/a69b5db0208f4fdca63285b1865a5a19
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/911b21dd9d68461c841613d1c1ba8754
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/35a61d738c8a4bb5bf19febe923d0015
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Skeletal muscle cells have long been considered to be made primarily of many individual, parallel myofibrils. Here, the authors show that the striated muscle contractile machinery forms a highly branched, mesh-like myofibrillar matrix connected acros
Externí odkaz:
https://doaj.org/article/519019aa3ec64184a9cc2d564f6dc75a
Publikováno v:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 377(1864)
The heart meets the high energy demands of constant muscle contraction and calcium cycling primarily through the conversion of fatty acids into adenosine triphosphate (ATP) by a large volume of mitochondria. As such, the spatial relationships among l
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Assessing biological circuit connections in single cells has been intractable due to lack of appropriate tools. Here, Bleck et al. develop a method to assess mitochondrial network connectivity in muscle cells and observe clear differences consistent
Externí odkaz:
https://doaj.org/article/fecf9499a27d4346b4b6ab29516b9f1b
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Mitochondria are key determinants of cellular health. However, the functional role of mitochondria varies from cell to cell depending on the relative demands for energy distribution, metabolite biosynthesis, and/or signaling. In order to support the
Externí odkaz:
https://doaj.org/article/d3ee892f3ef24eb6897982c946a9faf4
Publikováno v:
Molecular Biology Reports. 50:3179-3187
Publikováno v:
Physiology. 38
Friedreich’s ataxia (FRDA) is a rare genetic disorder that progressively develops cardiac hypertrophy and dysfunction (i.e., cardiomyopathy) along with neurodegenerative problems. Although this disease is largely caused by mitochondrial dysfunction
Publikováno v:
Neurotoxicology
Iron is a key element for mitochondrial function and homeostasis, which is also crucial for maintaining the neuronal system, but too much iron promotes oxidative stress. A large body of evidence has indicated that abnormal iron accumulation in the br