Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Yuhki, Saito"'
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112050- (2023)
Summary: We describe a patient haploinsufficient for the neuronal RNA binding protein NOVA1 who developed a behavioral motor hyperactivity disorder, suggesting a role of NOVA1 in postnatal motor inhibition. To investigate Nova1’s action in adult Ga
Externí odkaz:
https://doaj.org/article/1eb49e5d7a4b46a2915023fcaf033c37
Autor:
Yuhki Saito, Yanhong Yang, Misa Saito, Park, Christopher Y., Kosuke Funato, Tabar, Viviane, Darnell, Robert B.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 3/5/2024, Vol. 121 Issue 10, p1-7, 11p
Autor:
Keiko Honda, Yuhki Saito, Haruka Saito, Megumi Toyoda, Ruriko Abe, Takashi Saito, Takaomi C. Saido, Makoto Michikawa, Hidenori Taru, Yuriko Sobu, Saori Hata, Tadashi Nakaya, Toshiharu Suzuki
Publikováno v:
Neurobiology of Aging. 123:63-74
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::874979664c20ded1c9009ca31d15167f
https://doi.org/10.1016/j.neurobiolaging.2022.12.003
https://doi.org/10.1016/j.neurobiolaging.2022.12.003
Autor:
Yuan Yuan, Shirley Xie, Jennifer C. Darnell, Andrew J. Darnell, Yuhki Saito, Hemali Phatnani, Elisabeth A. Murphy, Chaolin Zhang, Tom Maniatis, Robert B. Darnell
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-19 (2018)
Abstract Background Alternative RNA processing plays an essential role in shaping cell identity and connectivity in the central nervous system. This is believed to involve differential regulation of RNA processing in various cell types. However, in v
Externí odkaz:
https://doaj.org/article/cb685f73162747c5a46387f6f24edeab
Autor:
Hun-Way Hwang, Christopher Y. Park, Hani Goodarzi, John J. Fak, Aldo Mele, Michael J. Moore, Yuhki Saito, Robert B. Darnell
Publikováno v:
Cell Reports, Vol 15, Iss 2, Pp 423-435 (2016)
Accurate and precise annotation of 3′ UTRs is critical for understanding how mRNAs are regulated by microRNAs (miRNAs) and RNA-binding proteins (RBPs). Here, we describe a method, poly(A) binding protein-mediated mRNA 3′ end retrieval by crosslin
Externí odkaz:
https://doaj.org/article/66d95c501fab4a868808f7ec2fad7949
Autor:
Yuhki Saito, Ben R. Hawley, M. Rhyan Puno, Shreya N. Sarathy, Christopher D. Lima, Samie R. Jaffrey, Robert B. Darnell, Scott Keeney, Devanshi Jain
Publikováno v:
Genes & Development. 36:180-194
Mechanisms regulating meiotic progression in mammals are poorly understood. The N6-methyladenosine (m6A) reader and 3′ → 5′ RNA helicase YTHDC2 switches cells from mitotic to meiotic gene expression programs and is essential for meiotic entry,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa0a85f8cc77c9b57f29c1d63f9b34bd
https://doi.org/10.1101/gad.349190.121
https://doi.org/10.1101/gad.349190.121
Autor:
Michel C. Nussenzweig, Caryn R Hale, Christian Gaebler, Paul D. Bieniasz, Dennis Schaefer-Babajew, Richard P. Lifton, Robert B. Darnell, Frauke Muecksch, Justin DaSilva, Erin G. Conlon, Ezgi Hacisuleyman, Theodora Hatziioannou, Yuhki Saito, Nathalie E. Blachère, Marissa Bergh
Publikováno v:
New England Journal of Medicine. 384:2212-2218
Emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are of clinical concern. In a cohort of 417 persons who had received the second dose of BNT162b2 (Pfizer-BioNTech) or mRNA-1273 (Moderna) vaccine at least 2 weeks previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abf1738aa0d424d55f69cb942efe6865
https://doi.org/10.1056/nejmoa2105000
https://doi.org/10.1056/nejmoa2105000
Autor:
Yuhki Saito, Soledad Miranda-Rottmann, Matteo Ruggiu, Christopher Y Park, John J Fak, Ru Zhong, Jeremy S Duncan, Brian A Fabella, Harald J Junge, Zhe Chen, Roberto Araya, Bernd Fritzsch, A J Hudspeth, Robert B Darnell
Publikováno v:
eLife, Vol 5 (2016)
The neuron specific RNA-binding proteins NOVA1 and NOVA2 are highly homologous alternative splicing regulators. NOVA proteins regulate at least 700 alternative splicing events in vivo, yet relatively little is known about the biologic consequences of
Externí odkaz:
https://doaj.org/article/53a008d0115a4c659aae01c373fb5e9f
Autor:
Janelle C Leggere, Yuhki Saito, Robert B Darnell, Marc Tessier-Lavigne, Harald J Junge, Zhe Chen
Publikováno v:
eLife, Vol 5 (2016)
RNA-binding proteins (RBPs) control multiple aspects of post-transcriptional gene regulation and function during various biological processes in the nervous system. To further reveal the functional significance of RBPs during neural development, we c
Externí odkaz:
https://doaj.org/article/1672d5b911334145abbe91cbcee807b2
Autor:
Haruka Saito, Yuhki Saito, Tohru Yamamoto, Toshiharu Suzuki, Fumio Matsuzaki, Mayo Shigeta, Saori Hata, Chiaki Murayama, Naoya Gotoh, Takaya Abe, Daijiro Konno, Daiki Ojima
Publikováno v:
J Biol Chem
Alzheimer's disease (AD) is a very common neurodegenerative disorder, chiefly caused by increased production of neurotoxic β-amyloid (Aβ) peptide generated from proteolytic cleavage of β-amyloid protein precursor (APP). Except for familial AD aris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2137251d515fd1f9dad773a9ba98549
https://doi.org/10.1074/jbc.ra119.012386
https://doi.org/10.1074/jbc.ra119.012386